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Database: UniProt/TrEMBL
Entry: A0A1S3JEN4_LINUN
LinkDB: A0A1S3JEN4_LINUN
Original site: A0A1S3JEN4_LINUN 
ID   A0A1S3JEN4_LINUN        Unreviewed;      1153 AA.
AC   A0A1S3JEN4;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   30-AUG-2017, entry version 4.
DE   RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00818223};
DE            EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00818223};
GN   Name=LOC106172630 {ECO:0000313|RefSeq:XP_013408875.1};
OS   Lingula unguis.
OC   Eukaryota; Metazoa; Lophotrochozoa; Brachiopoda; Linguliformea;
OC   Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula.
OX   NCBI_TaxID=7574 {ECO:0000313|Proteomes:UP000085678, ECO:0000313|RefSeq:XP_013408875.1};
RN   [1] {ECO:0000313|RefSeq:XP_013408875.1}
RP   IDENTIFICATION.
RC   TISSUE=Gonads {ECO:0000313|RefSeq:XP_013408875.1};
RG   RefSeq;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY: Hydrolysis of an N(6)-acetyl-lysine residue of
CC       a histone to yield a deacetylated histone.
CC       {ECO:0000256|SAAS:SAAS00818219}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00818221}.
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DR   RefSeq; XP_013408875.1; XM_013553421.1.
DR   GeneID; 106172630; -.
DR   Proteomes; UP000085678; Genome assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.40.10; -; 1.
DR   Gene3D; 3.40.800.20; -; 2.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR001607; Znf_UBP.
DR   PANTHER; PTHR10625; PTHR10625; 1.
DR   Pfam; PF00850; Hist_deacetyl; 2.
DR   Pfam; PF02148; zf-UBP; 1.
DR   PRINTS; PR01270; HDASUPER.
DR   SMART; SM00290; ZnF_UBP; 1.
DR   PROSITE; PS50271; ZF_UBP; 1.
PE   4: Predicted;
KW   Chromatin regulator {ECO:0000256|SAAS:SAAS00818226};
KW   Complete proteome {ECO:0000313|Proteomes:UP000085678};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00490343};
KW   Nucleus {ECO:0000256|SAAS:SAAS00818233};
KW   Reference proteome {ECO:0000313|Proteomes:UP000085678};
KW   Transcription {ECO:0000256|SAAS:SAAS00818215};
KW   Transcription regulation {ECO:0000256|SAAS:SAAS00818213}.
FT   DOMAIN     1070   1131       UBP-type. {ECO:0000259|PROSITE:PS50271}.
FT   ZN_FING    1070   1131       UBP-type. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00502}.
SQ   SEQUENCE   1153 AA;  128095 MW;  C5B467F77552CDC0 CRC64;
     MDPPIINKGS PASEPDSASS DPKATGLVQT ENPSPNSCEG GVGDAPAPAP QTKSDETPSN
     VKTQSVKPKK SASTGKKKGK QSKGPTLEEL KRRGRDTRQH PHQDNIQIMD KMADLSMKSM
     KLTNLGTGLI YDHFMTQHRC EWDLLHPECP DRITEPYLRC LQYGLVTRCV PILPKKSVDE
     AALSQHSPEY LKLLKDSQFL SEIQPLQDLS EKYHGIYFNS PKMTSEKGHL PEHFLPRGVQ
     TLQDLSGKYD SIYFNSKTFE CAQLSLGSTI EMTEQILQEK VRNGFAIVRP PGHHAMYKEA
     CGYCFFNNVA IAAKRALDKF GLERVLIVDW DVHHGQGTQY MFYDDPRVMY VSIHRYEYGN
     FWPNLRESDY DYIGEGRGTG YNINIPLNKT GMTNSDYMAV FHQLLMPIFY EYNPQLVLVS
     SGYDAAIGCP EGEMEVTPAC YAHFINMLSA LADGKLAVIL EGGYCLKSLS EGVALTLRAL
     LGDPTPRIGP LQQPNDVIKK TILNAIRVLR PYWQCLQFQG VLPVQSAEVS STTQEDEHLR
     TVPFSTPENR PEVYPIDECC YPVQEPEVKA TYSARIQELI DNTYLGKAPH RTALVYDEVM
     RKHKNHVDPG HPERPDRITK IYNKIQEYRL LKHCLRVESR MATDEEVLTC HKTEHFKKMQ
     QIKETKPREL KEVQLQYNSV YLCQESYDCA LLAVGSLLNV VEAVLTNKSQ NGVAVIRPPG
     HHAEINQACG FCLFNNVAIA ARYAQKTFGV KKVLILDWDV HHGNGIQHIF EDDPSVLYIS
     IHRYDQGFFF PAGPDGNYDK VGNGAGAGFN INIPWNKYGM GDAEYIAAFL QVIMPVAYEF
     DPDLVLVSAG FDAARGDPLG HCDITPAGYG HMTQMLMSLA NGRVILALEG GYNLHSISES
     MAMCTKVLLG GTCPPLGSLV PKTMAVESIC NVLDTHKKYW KCLQFRVDLP APVLPVTAGV
     QNNAVTSTSD MDSLTTAIGA LQVKYESVSS SSDGGSFLSS PTVTSSDCTG DSPLGACGGS
     EAKNLTVREL LGGALADQDD LQMFAVVPLP WCEHLKMVAP PPERGLDVFA ACSMCESTKE
     NWVCLTCYEV CCGRYVNEHM LFHGLSTEHK MVLSYSDLSV WCYGCDAYIH NEIIVPHKRA
     AHRSKFGEDI PGV
//
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