ID A0A1U7RZU6_ALLSI Unreviewed; 512 AA.
AC A0A1U7RZU6;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Alpha-amylase {ECO:0000256|ARBA:ARBA00012595, ECO:0000256|RuleBase:RU361134};
DE EC=3.2.1.1 {ECO:0000256|ARBA:ARBA00012595, ECO:0000256|RuleBase:RU361134};
GN Name=LOC102375731 {ECO:0000313|RefSeq:XP_006032219.1,
GN ECO:0000313|RefSeq:XP_006032220.1};
OS Alligator sinensis (Chinese alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=38654 {ECO:0000313|RefSeq:XP_006032219.1};
RN [1] {ECO:0000313|RefSeq:XP_006032219.1, ECO:0000313|RefSeq:XP_006032220.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (APR-2022) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in
CC polysaccharides containing three or more (1->4)-alpha-linked D-
CC glucose units.; EC=3.2.1.1; Evidence={ECO:0000256|ARBA:ARBA00000548,
CC ECO:0000256|RuleBase:RU361134};
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- COFACTOR:
CC Name=chloride; Xref=ChEBI:CHEBI:17996;
CC Evidence={ECO:0000256|ARBA:ARBA00001923};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC {ECO:0000256|ARBA:ARBA00008061, ECO:0000256|RuleBase:RU003615}.
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DR RefSeq; XP_006032219.1; XM_006032157.3.
DR RefSeq; XP_006032220.1; XM_006032158.3.
DR STRING; 38654.A0A1U7RZU6; -.
DR GeneID; 102375731; -.
DR KEGG; asn:102375731; -.
DR eggNOG; KOG2212; Eukaryota.
DR OrthoDB; 3249969at2759; -.
DR Proteomes; UP000189705; Unplaced.
DR GO; GO:0004556; F:alpha-amylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd11317; AmyAc_bac_euk_AmyA; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR006048; A-amylase/branching_C.
DR InterPro; IPR031319; A-amylase_C.
DR InterPro; IPR006046; Alpha_amylase.
DR InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR43447; ALPHA-AMYLASE; 1.
DR PANTHER; PTHR43447:SF49; ALPHA-AMYLASE; 1.
DR Pfam; PF00128; Alpha-amylase; 1.
DR Pfam; PF02806; Alpha-amylase_C; 1.
DR PRINTS; PR00110; ALPHAAMYLASE.
DR SMART; SM00642; Aamy; 1.
DR SMART; SM00632; Aamy_C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU361134};
KW Chloride {ECO:0000256|ARBA:ARBA00023214};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361134};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000189705};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..512
FT /note="Alpha-amylase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011902133"
FT DOMAIN 26..414
FT /note="Glycosyl hydrolase family 13 catalytic"
FT /evidence="ECO:0000259|SMART:SM00642"
FT DOMAIN 423..511
FT /note="Alpha-amylase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00632"
SQ SEQUENCE 512 AA; 57748 MW; 8FD67AD45952FD69 CRC64;
MKILLVLAAV GLCWAQYNPH TKPGRTSIVH LFEWRWADIA LECERYLAPN GFGGVQISPP
SENIIITNPW RPWWERYQPV SYKLCTRSGN EDEFRNMVTR CNNVGVHIYV DAVVNHMCGA
GAGSGNGGTC GSYFNAQTED FPAVPFSGWD FNDGKCKTGS GEIENYNDPY QVRDCRLVSL
LDLALEKDYV RSKIAEYMNY LIDIGVAGFR IDASKHMWPG DMKAFLDKLK NLNTQWFSSG
SKPFIYQEVI DLGGEPIKSS EYFGNGRVTE FKYSAKLGTV IRKWNGEKMA YLRNWGEGWG
LMPSDKALVF VDNHDNQRGH GAGGASVLTF WDPRQYKMAT GFMLAHPYGF TRVMSSFWWP
RDFQNGKDIN DWVGPPSFED GTTKPVTVNP DTTCGNGWVC EHRWRQIRNM VIFRNVVDGQ
PFSNWWDNNS NQVAFGRGNK GFIVFNNDDW YMNINLNTGL PAGTYCDVIS GQKEGNHCTG
IQVHIGADGV ANFQISNQAE DPFIAIHVDA KL
//
