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Database: UniProt/TrEMBL
Entry: A0A1U8IDJ4_GOSHI
LinkDB: A0A1U8IDJ4_GOSHI
Original site: A0A1U8IDJ4_GOSHI 
ID   A0A1U8IDJ4_GOSHI        Unreviewed;       418 AA.
AC   A0A1U8IDJ4;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   22-NOV-2017, entry version 7.
DE   RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283};
DE            EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};
GN   Name=LOC107893401 {ECO:0000313|RefSeq:XP_016673869.1,
GN   ECO:0000313|RefSeq:XP_016673870.1};
OS   Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae;
OC   Gossypium.
OX   NCBI_TaxID=3635 {ECO:0000313|Proteomes:UP000189702, ECO:0000313|RefSeq:XP_016673869.1};
RN   [1] {ECO:0000313|Proteomes:UP000189702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX   PubMed=25893780; DOI=10.1038/nbt.3208;
RA   Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H.,
RA   Ma X., Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W.,
RA   Chen W., Du X., Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W.,
RA   Wei H., Wei S., Huang G., Zhang X., Zhu S., Zhang H., Sun F., Wang X.,
RA   Liang J., Wang J., He Q., Huang L., Wang J., Cui J., Song G., Wang K.,
RA   Xu X., Yu J.Z., Zhu Y., Yu S.;
RT   "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT   provides insights into genome evolution.";
RL   Nat. Biotechnol. 33:524-530(2015).
RN   [2] {ECO:0000313|RefSeq:XP_016673869.1, ECO:0000313|RefSeq:XP_016673870.1}
RP   IDENTIFICATION.
RC   TISSUE=Leaf {ECO:0000313|RefSeq:XP_016673869.1,
RC   ECO:0000313|RefSeq:XP_016673870.1};
RG   RefSeq;
RL   Submitted (APR-2017) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY: Hydrolysis of an N(6)-acetyl-lysine residue of
CC       a histone to yield a deacetylated histone.
CC       {ECO:0000256|SAAS:SAAS00894227}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00894298}.
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DR   RefSeq; XP_016673869.1; XM_016818380.1.
DR   RefSeq; XP_016673870.1; XM_016818381.1.
DR   GeneID; 107893401; -.
DR   KEGG; ghi:107893401; -.
DR   KO; K11418; -.
DR   Proteomes; UP000189702; Genome assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:UniProtKB-EC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.800.20; -; 1.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   Pfam; PF00850; Hist_deacetyl; 1.
DR   PRINTS; PR01270; HDASUPER.
DR   SUPFAM; SSF52768; SSF52768; 1.
PE   4: Predicted;
KW   Chromatin regulator {ECO:0000256|SAAS:SAAS00894233};
KW   Complete proteome {ECO:0000313|Proteomes:UP000189702};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00870288};
KW   Nucleus {ECO:0000256|SAAS:SAAS00894277};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW   Transcription {ECO:0000256|SAAS:SAAS00894309};
KW   Transcription regulation {ECO:0000256|SAAS:SAAS00894290}.
FT   DOMAIN      132    396       Hist_deacetyl. {ECO:0000259|Pfam:
FT                                PF00850}.
SQ   SEQUENCE   418 AA;  46733 MW;  830E0C66E0D41175 CRC64;
     MTFPLLTLSP QQPFWKFRTH RVIANTTEST RNLCKSTLYL FLALATPFIA YRCFNSSTMF
     WSSSSSSSQP ATKIDADSLR RQRINSSKLY QPDASSKVPV IYSSYYDISF LGIEKLHPFD
     SSKWGRICRF LMSEGYLEKN SIVDPLEAST EDLLVVHTEA YLNSLKNSVN VARITEVPPV
     AMLPNWLVQM EVLYPFRRQV GGTVLAAKLA KDQGWAINVG GGFHHCSGDR GGGFCAYADI
     SLCIHFAFVR LNISRVMIID LDAHQGNGHE RDFGNDERVY ILDMYNPGIY PFDMTARNYI
     NQKVEVMTGT TTDEYLKQLD KALAVAGSNF APELIVYNAG TDILDGDPLG GLKVSPDGVI
     QRDEKVFRFA RERNIPIVMV TSGGYMKTSA RVIANSIINL SKKGLIETNV HSGRKIMI
//
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