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Database: UniProt/TrEMBL
Entry: A0A1W3JG16_CIOIN
LinkDB: A0A1W3JG16_CIOIN
Original site: A0A1W3JG16_CIOIN 
ID   A0A1W3JG16_CIOIN        Unreviewed;       597 AA.
AC   A0A1W3JG16;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-SEP-2017, entry version 4.
DE   RecName: Full=Histone-lysine N-methyltransferase {ECO:0000256|PROSITE-ProRule:PRU00903};
DE            EC=2.1.1.43 {ECO:0000256|PROSITE-ProRule:PRU00903};
GN   Name=LOC100186975 {ECO:0000313|RefSeq:XP_002128107.1,
GN   ECO:0000313|RefSeq:XP_009861044.1};
OS   Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona;
OC   Phlebobranchia; Cionidae; Ciona.
OX   NCBI_TaxID=7719 {ECO:0000313|Proteomes:UP000192222, ECO:0000313|RefSeq:XP_009861044.1};
RN   [1] {ECO:0000313|RefSeq:XP_002128107.1, ECO:0000313|RefSeq:XP_009861044.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JUN-2017) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + L-lysine-[histone] =
CC       S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
CC       {ECO:0000256|PROSITE-ProRule:PRU00903}.
CC   -!- SIMILARITY: Belongs to the class V-like SAM-binding
CC       methyltransferase superfamily. Histone-lysine methyltransferase
CC       family. Suvar4-20 subfamily. {ECO:0000256|PROSITE-
CC       ProRule:PRU00903}.
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DR   RefSeq; XP_002128107.1; XM_002128071.1.
DR   RefSeq; XP_009861044.1; XM_009862742.1.
DR   UniGene; Cin.22078; -.
DR   GeneID; 100186975; -.
DR   KEGG; cin:100186975; -.
DR   KO; K11429; -.
DR   Proteomes; UP000192222; Genome assembly.
DR   GO; GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IEA:UniProtKB-UniRule.
DR   GO; GO:0034773; P:histone H4-K20 trimethylation; IEA:UniProtKB-UniRule.
DR   InterPro; IPR025790; Hist-Lys_N-MTase_Suvar4-20.
DR   InterPro; IPR001214; SET_dom.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00317; SET; 1.
DR   PROSITE; PS51570; SAM_MT43_SUVAR420_2; 1.
DR   PROSITE; PS50280; SET; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000192222};
KW   Methyltransferase {ECO:0000256|PROSITE-ProRule:PRU00903,
KW   ECO:0000313|RefSeq:XP_002128107.1, ECO:0000313|RefSeq:XP_009861044.1};
KW   S-adenosyl-L-methionine {ECO:0000256|PROSITE-ProRule:PRU00903};
KW   Transferase {ECO:0000256|PROSITE-ProRule:PRU00903,
KW   ECO:0000313|RefSeq:XP_002128107.1, ECO:0000313|RefSeq:XP_009861044.1}.
FT   DOMAIN      122    239       SET. {ECO:0000259|PROSITE:PS50280}.
SQ   SEQUENCE   597 AA;  67742 MW;  93181DE590E1C5EC CRC64;
     MVVSPLNCAP AKISQHTSKY SPSTNMNARE LCDNDDLATS LVLDPYLGFA THKMNTRFRS
     VRGRNDELAI TIEEFHFVPN YEDTYNKLVS GEWSRLYFMN KSSRQQQVFK NHVFRYLGMF
     DPECGFSIQP CNRYTLEDGG AKIVSTRDWC KNDKMNLLVG CIAELTKDDE SSLLVPGRND
     FSVMFSTRKN CAQLWLGPAS FINHDCRPNC CFVSTGRDTA CVRVLRDILP GEEITCFYGE
     SFFGDKNCFC ECETCERRKT GAYRPKDGSK SDVPMTFSNK YGLRETDKRL HRLQKERKSN
     KLPSSHKLVK RDPSPSCSEF SMSSEDSSEY FTCSESGRSV TDFDSSSTSS EEIRGVTVRL
     SKSVKRSASP VVRNAKRQKT SVYTNLFEPY YYEKGDSPQV GTHRRKQTPP IKLSDQYHGN
     ASFISKGIRY GALTASLLPY RSKPEPLDST SVRRSPRLTF HGKPDVQKSK KVTEDFLPKA
     EVRLPRLEST HAEPMELRSK GQSSKARNLW SDNGFLPLCV EMRGSDWVKT GETPDWGQTE
     IQNGKTSINY DSTLSRKDNG VPKLTIRKVS KNGKKLKETG RLKLMLGAER IHVNLLK
//
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