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Database: UniProt/TrEMBL
Entry: A0A1W6XGW5_9RHIZ
LinkDB: A0A1W6XGW5_9RHIZ
Original site: A0A1W6XGW5_9RHIZ 
ID   A0A1W6XGW5_9RHIZ        Unreviewed;       381 AA.
AC   A0A1W6XGW5;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-SEP-2017, entry version 3.
DE   RecName: Full=Alanine racemase {ECO:0000256|HAMAP-Rule:MF_01201};
DE            EC=5.1.1.1 {ECO:0000256|HAMAP-Rule:MF_01201};
GN   ORFNames=A9K65_030475 {ECO:0000313|EMBL:ARP68091.1};
OS   Mesorhizobium sp. WSM1497.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Phyllobacteriaceae; Mesorhizobium.
OX   NCBI_TaxID=278153 {ECO:0000313|EMBL:ARP68091.1, ECO:0000313|Proteomes:UP000093884};
RN   [1] {ECO:0000313|EMBL:ARP68091.1, ECO:0000313|Proteomes:UP000093884}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSM1497 {ECO:0000313|EMBL:ARP68091.1,
RC   ECO:0000313|Proteomes:UP000093884};
RA   Brewer R., Haskett T.L., Ramsay J.P., O'Hara G.W., Terpolilli J.;
RT   "Complete genome sequence of Mesorhizobium sp. WSM1497.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the interconversion of L-alanine and D-
CC       alanine. May also act on other amino acids. {ECO:0000256|HAMAP-
CC       Rule:MF_01201}.
CC   -!- CATALYTIC ACTIVITY: L-alanine = D-alanine. {ECO:0000256|HAMAP-
CC       Rule:MF_01201}.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01201,
CC         ECO:0000256|PIRSR:PIRSR600821-50,
CC         ECO:0000256|SAAS:SAAS00758845};
CC   -!- PATHWAY: Amino-acid biosynthesis; D-alanine biosynthesis; D-
CC       alanine from L-alanine: step 1/1. {ECO:0000256|HAMAP-
CC       Rule:MF_01201}.
CC   -!- SIMILARITY: Belongs to the alanine racemase family.
CC       {ECO:0000256|HAMAP-Rule:MF_01201}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|HAMAP-Rule:MF_01201}.
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DR   EMBL; CP021070; ARP68091.1; -; Genomic_DNA.
DR   RefSeq; WP_064993325.1; NZ_LYTN01000006.1.
DR   UniPathway; UPA00042; UER00497.
DR   Proteomes; UP000093884; Chromosome.
DR   GO; GO:0008784; F:alanine racemase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030632; P:D-alanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 2.40.37.10; -; 1.
DR   Gene3D; 3.20.20.10; -; 1.
DR   HAMAP; MF_01201; Ala_racemase; 1.
DR   InterPro; IPR000821; Ala_racemase.
DR   InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR   InterPro; IPR011079; Ala_racemase_C.
DR   InterPro; IPR001608; Ala_racemase_N.
DR   InterPro; IPR029066; PLP-binding_barrel.
DR   Pfam; PF00842; Ala_racemase_C; 1.
DR   Pfam; PF01168; Ala_racemase_N; 1.
DR   PRINTS; PR00992; ALARACEMASE.
DR   SMART; SM01005; Ala_racemase_C; 1.
DR   SUPFAM; SSF50621; SSF50621; 1.
DR   SUPFAM; SSF51419; SSF51419; 1.
DR   TIGRFAMs; TIGR00492; alr; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000093884};
KW   Isomerase {ECO:0000256|HAMAP-Rule:MF_01201,
KW   ECO:0000256|SAAS:SAAS00630647};
KW   Pyridoxal phosphate {ECO:0000256|HAMAP-Rule:MF_01201,
KW   ECO:0000256|PIRSR:PIRSR600821-50, ECO:0000256|SAAS:SAAS00722456}.
FT   DOMAIN      253    381       Ala_racemase_C. {ECO:0000259|SMART:
FT                                SM01005}.
FT   ACT_SITE     51     51       Proton acceptor; specific for D-alanine.
FT                                {ECO:0000256|HAMAP-Rule:MF_01201}.
FT   BINDING     145    145       Substrate. {ECO:0000256|HAMAP-Rule:
FT                                MF_01201}.
FT   MOD_RES      51     51       N6-(pyridoxal phosphate)lysine.
FT                                {ECO:0000256|HAMAP-Rule:MF_01201,
FT                                ECO:0000256|PIRSR:PIRSR600821-50}.
SQ   SEQUENCE   381 AA;  41048 MW;  EE75EFB278257388 CRC64;
     MCALTSIATV QSKKAASREA CYEIDLGAIR HNYRQLRRHL PRTVKIFACL KRNGYGCGAG
     PVARTLATEG ADGFAVATLP DAMAIREMGI DLPVLLYPGP LPTSAKTIEA LGLTVTVSSL
     NELESWRAAM SVTRIFVKAD LGFFRAGATP QEIGRLLAAA HVCNDVEVQG LYAHLSELPT
     SVTSDASEQF SRLQRILQDA EASGTRPPII MMSSTAGVLR HPAMDLDAVD PGALFIGLPE
     TDRPMRAVTL RPALKAISTC LVSVKRIDAS LGPIPDIPGF RSGMTIGVLG MGWGDGLPRH
     VPAQAEALVR GQRARLLPPA HLEHLRIDLT DVPDARFGDQ VLLLGQQAHQ TITHEEVAAQ
     WGTDLIGLYA QLRDHIPRVY V
//
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