ID A0A1X7VB57_AMPQE Unreviewed; 1023 AA.
AC A0A1X7VB57;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Hydantoinase/oxoprolinase N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=100632786 {ECO:0000313|EnsemblMetazoa:Aqu2.1.36762_001};
OS Amphimedon queenslandica (Sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Haplosclerida; Niphatidae; Amphimedon.
OX NCBI_TaxID=400682 {ECO:0000313|EnsemblMetazoa:Aqu2.1.36762_001, ECO:0000313|Proteomes:UP000007879};
RN [1] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20686567; DOI=10.1038/nature09201;
RA Srivastava M., Simakov O., Chapman J., Fahey B., Gauthier M.E., Mitros T.,
RA Richards G.S., Conaco C., Dacre M., Hellsten U., Larroux C., Putnam N.H.,
RA Stanke M., Adamska M., Darling A., Degnan S.M., Oakley T.H.,
RA Plachetzki D.C., Zhai Y., Adamski M., Calcino A., Cummins S.F.,
RA Goodstein D.M., Harris C., Jackson D.J., Leys S.P., Shu S., Woodcroft B.J.,
RA Vervoort M., Kosik K.S., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The Amphimedon queenslandica genome and the evolution of animal
RT complexity.";
RL Nature 466:720-726(2010).
RN [2] {ECO:0000313|Proteomes:UP000007879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., Glavina del Rio T.,
RA Bruce D., Barry K., Pitluck S., Srivastava M., Simakov O., Chapman J.,
RA Mitros T., Hellsten U., Putnam N.H., Fahey B., Gauthier M., Larroux C.,
RA Richards G.S., Stanke M., Adamska M., Darling A., Dacre M., Degnan S.M.,
RA Zhai Y., Adamski M., Calcino A., Cummins S.F., Goodstein D.M., Harris C.,
RA Shu S., Woodcroft B., Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.;
RT "The genome of the haplosclerid demosponge Amphimedon queenslandica and the
RT evolution of animal complexity.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:Aqu2.1.36762_001}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2017) to UniProtKB.
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DR RefSeq; XP_019849930.1; XM_019994371.1.
DR AlphaFoldDB; A0A1X7VB57; -.
DR EnsemblMetazoa; Aqu2.1.36762_001; Aqu2.1.36762_001; Aqu2.1.36762.
DR GeneID; 100632786; -.
DR KEGG; aqu:100632786; -.
DR eggNOG; ENOG502QQBE; Eukaryota.
DR InParanoid; A0A1X7VB57; -.
DR OrthoDB; 307246at2759; -.
DR Proteomes; UP000007879; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 2.40.390.10; CV3147-like; 1.
DR Gene3D; 3.40.1610.10; CV3147-like domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR048350; DUF917_C.
DR InterPro; IPR024071; DUF917_C_sf.
DR InterPro; IPR010318; DUF917_N.
DR InterPro; IPR027479; DUF917_N_sf.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR PANTHER; PTHR11365:SF10; HYDANTOINASE; 1.
DR Pfam; PF06032; DUF917; 2.
DR Pfam; PF20906; DUF917_C; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF160991; CV3147-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007879}.
FT DOMAIN 5..177
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 198..382
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 613..700
FT /note="DUF917"
FT /evidence="ECO:0000259|Pfam:PF06032"
FT DOMAIN 749..820
FT /note="DUF917"
FT /evidence="ECO:0000259|Pfam:PF06032"
FT DOMAIN 826..1017
FT /note="DUF917"
FT /evidence="ECO:0000259|Pfam:PF20906"
SQ SEQUENCE 1023 AA; 109528 MW; BB3EF1F4D310ADFD CRC64;
MELVLGVDVG GTYTDAVVVS GRKVISSCKR QTTLNRTEGI VSAIKGAIGN CNSQDIVRVC
IGTTHFINAV VERSVDKLSR VAVVRLCGPA SIALPPFSDF PSDLSSLVKA SVHMISGGLE
YNGSFISHLS VDEIKELGVD FLSRSSPVTN IVISGVFSPM TNPDSNQEVK VANILHSVSD
SFSITLASKI GKLGILEREN AAILNESLKA FSRRTIDEFK AALQSLQLNC PFYLTQNDGT
LISVDEALEY PIFTFSSGST NSMRGAMFLS GKEDGIVVDI GGTTTDVGVL VKGFPREASS
QVKIGGVKTN FRVPNVVSIG LGGGSLVVSS DNSGEIQVGP NSVGMNLTSK AICFGGDVCT
ATDIALAAGI CEDNNLPSNK KKEIISKFGG IIYPAMRNIH LKIEEVIDLV KTNKEDAVVI
LVGGGSILVD IKQSLKGAMR FIKPPHFEVA NAVGAALGMI AGYSDSVESL SEAMKKVKVE
FQDKPENEIR DEAQRRLVKE CIDKAIENAR QKGCHPGSEY VHEQSVMDVT YVPDMLRISV
KVIGLLKDQQ NLKVDDLATE SKAVQDKSVS PSASTDSVWP YQCMKDITLD NEANLPPPRV
NKDTGEWLLN EVDVECISIG AGILGCGGGG SPSIGCVAAL NALKEGKEIK IVNPFRCKGG
ENCDLIAAVA FMGAPAVLCE KLFNGTETTL CLKTMQRLLA AGLYGGENDI DKLSSKGISA
SFFNLENKNQ ACIIDESTLP EITSETKRAR QITGLMSAEI GGMNSIEPLL VGANMKLPVL
DADGMGRAFP ELQMYVPFMN GLNSYPCCVA SEKGEIYVVS HVHTSKDLED ILRIKCVEMG
MTCGICLPPV TLDEMFKDCI IHSYSRAWQL GRCVMRARKS HSNVVQAITK QQNGILLLTG
KVVDIVRVTE GAFTGSVFII KGTGLYSMFS IQINAKNENL VAREVNDNGA VGRVLATTPD
LITVVDSDSG YPITTEEVKY GLRVSVLVLP ADPKLLTDKA ISVVGPQGFQ MSDIDYIAPV
SLL
//
