ID   A0LU98_ACIC1            Unreviewed;       269 AA.
AC   A0LU98;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   01-MAY-2013, entry version 50.
DE   RecName: Full=Pseudouridine synthase;
DE            EC=5.4.99.-;
GN   OrderedLocusNames=Acel_1236;
OS   Acidothermus cellulolyticus (strain ATCC 43068 / 11B).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Frankineae; Acidothermaceae; Acidothermus.
OX   NCBI_TaxID=351607;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43068 / 11B;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Zharchuk I., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Mikhailova N., Berry A.M., Adney W.S., Normand P.,
RA   Leu D., Pujic P., Richardson P.;
RT   "Complete sequence of Acidothermus cellulolyticus 11B.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the pseudouridine synthase rsuA family.
CC   -!- SIMILARITY: Contains 1 S4 RNA-binding domain.
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DR   EMBL; CP000481; ABK53008.1; -; Genomic_DNA.
DR   RefSeq; YP_872994.1; NC_008578.1.
DR   ProteinModelPortal; A0LU98; -.
DR   STRING; 351607.Acel_1236; -.
DR   EnsemblBacteria; ABK53008; ABK53008; Acel_1236.
DR   GeneID; 4486684; -.
DR   KEGG; ace:Acel_1236; -.
DR   PATRIC; 20672956; VBIAciCel132453_1313.
DR   eggNOG; COG1187; -.
DR   HOGENOM; HOG000044954; -.
DR   KO; K06178; -.
DR   OMA; VHEGRTH; -.
DR   BioCyc; ACEL351607:GIXW-1263-MONOMER; -.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   Gene3D; 3.10.290.10; -; 1.
DR   InterPro; IPR020103; PsdUridine_synth_cat_dom.
DR   InterPro; IPR000748; PsdUridine_synth_RsuA/RluB/E/F.
DR   InterPro; IPR018496; PsdUridine_synth_RsuA/RluB_CS.
DR   InterPro; IPR006145; PsdUridine_synth_RsuA/RluD.
DR   InterPro; IPR002942; S4_RNA-bd.
DR   Pfam; PF00849; PseudoU_synth_2; 1.
DR   Pfam; PF01479; S4; 1.
DR   SMART; SM00363; S4; 1.
DR   SUPFAM; SSF55120; PsdUridine_synth_cat_dom; 1.
DR   TIGRFAMs; TIGR00093; TIGR00093; 1.
DR   PROSITE; PS01149; PSI_RSU; 1.
DR   PROSITE; PS50889; S4; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Isomerase; RNA-binding.
SQ   SEQUENCE   269 AA;  28652 MW;  A425E732CA393ED1 CRC64;
     MSNTRSSPGP RGLAPHSRAA ALSLPAGDDG AVRLQKVLAA AGVGSRRACE ELIAAGRVEV
     DGVPVTRLGV RVDPQTAVIR VDGKRIPPAT PFAYFALNKP RGVVTTMSDP RGRPCVGDLV
     ADLPVRVFHV GRLDTDSEGL LLLTNDGRLT HRLTHPSHAV PKTYVADVEG RLGRTGVHLL
     RSGVDLADGP AQADAVRILE RYGARTLVEV VVHEGRTHLV RRMLAAVGHP VRRLVRTAIG
     PVALGQLRPG ARRQLTPREL GELLDLVGL
//