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Database: UniProt/TrEMBL
Entry: A1JQZ8_YERE8
LinkDB: A1JQZ8_YERE8
Original site: A1JQZ8_YERE8 
ID   A1JQZ8_YERE8            Unreviewed;       313 AA.
AC   A1JQZ8;
DT   06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2007, sequence version 1.
DT   25-OCT-2017, entry version 75.
DE   RecName: Full=Glutaminase {ECO:0000256|HAMAP-Rule:MF_00313, ECO:0000256|SAAS:SAAS00041476};
DE            EC=3.5.1.2 {ECO:0000256|HAMAP-Rule:MF_00313, ECO:0000256|SAAS:SAAS00041476};
GN   Name=glsA {ECO:0000256|HAMAP-Rule:MF_00313};
GN   OrderedLocusNames=YE3691 {ECO:0000313|EMBL:CAL13718.1};
OS   Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 /
OS   8081).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=393305 {ECO:0000313|EMBL:CAL13718.1, ECO:0000313|Proteomes:UP000000642};
RN   [1] {ECO:0000313|EMBL:CAL13718.1, ECO:0000313|Proteomes:UP000000642}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 13174 / 8081 {ECO:0000313|Proteomes:UP000000642};
RX   PubMed=17173484; DOI=10.1371/journal.pgen.0020206;
RA   Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L.,
RA   Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T.,
RA   Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S.,
RA   Sanders M., Whitehead S., Quail M.A., Dougan G., Parkhill J.,
RA   Prentice M.B.;
RT   "The complete genome sequence and comparative genome analysis of the
RT   high pathogenicity Yersinia enterocolitica strain 8081.";
RL   PLoS Genet. 2:2039-2051(2006).
CC   -!- CATALYTIC ACTIVITY: L-glutamine + H(2)O = L-glutamate + NH(3).
CC       {ECO:0000256|HAMAP-Rule:MF_00313, ECO:0000256|SAAS:SAAS00062832}.
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00313,
CC       ECO:0000256|SAAS:SAAS00559507}.
CC   -!- SIMILARITY: Belongs to the glutaminase family. {ECO:0000256|HAMAP-
CC       Rule:MF_00313, ECO:0000256|SAAS:SAAS00551679}.
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DR   EMBL; AM286415; CAL13718.1; -; Genomic_DNA.
DR   RefSeq; WP_011817230.1; NC_008800.1.
DR   RefSeq; YP_001007846.1; NC_008800.1.
DR   ProteinModelPortal; A1JQZ8; -.
DR   STRING; 393305.YE3691; -.
DR   EnsemblBacteria; CAL13718; CAL13718; YE3691.
DR   GeneID; 4714090; -.
DR   KEGG; yen:YE3691; -.
DR   PATRIC; fig|393305.7.peg.3931; -.
DR   eggNOG; ENOG4105CSV; Bacteria.
DR   eggNOG; COG2066; LUCA.
DR   HOGENOM; HOG000216890; -.
DR   KO; K01425; -.
DR   OMA; MYTCGMY; -.
DR   OrthoDB; POG091H02PU; -.
DR   Proteomes; UP000000642; Chromosome.
DR   GO; GO:0004359; F:glutaminase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:InterPro.
DR   HAMAP; MF_00313; Glutaminase; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR015868; Glutaminase.
DR   PANTHER; PTHR12544; PTHR12544; 1.
DR   Pfam; PF04960; Glutaminase; 1.
DR   SUPFAM; SSF56601; SSF56601; 1.
DR   TIGRFAMs; TIGR03814; Gln_ase; 1.
PE   3: Inferred from homology;
KW   Acetylation {ECO:0000256|HAMAP-Rule:MF_00313};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000642};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_00313,
KW   ECO:0000256|SAAS:SAAS00041473}.
FT   BINDING      67     67       Substrate. {ECO:0000256|HAMAP-Rule:
FT                                MF_00313}.
FT   BINDING     118    118       Substrate. {ECO:0000256|HAMAP-Rule:
FT                                MF_00313}.
FT   BINDING     162    162       Substrate. {ECO:0000256|HAMAP-Rule:
FT                                MF_00313}.
FT   BINDING     169    169       Substrate. {ECO:0000256|HAMAP-Rule:
FT                                MF_00313}.
FT   BINDING     193    193       Substrate. {ECO:0000256|HAMAP-Rule:
FT                                MF_00313}.
FT   BINDING     245    245       Substrate. {ECO:0000256|HAMAP-Rule:
FT                                MF_00313}.
FT   BINDING     263    263       Substrate; via amide nitrogen.
FT                                {ECO:0000256|HAMAP-Rule:MF_00313}.
SQ   SEQUENCE   313 AA;  33009 MW;  67B72D5B2110C0B5 CRC64;
     MTIDLARLNH VVKDSYSQYS TLAGGANASY IPYLASVPSQ LAGLAIVTID GDIISQGDTD
     FRFALESISK VCSLALALED IGPQAVQDKI GADPTGLPFN SVIALELHNG KPLSPLVNAG
     AMSTVSAIKA SNREDRWARI LDMQQQLVGA PIALSDEVNH SEQTTNFHNR AIAWLLYSAQ
     AMYCDPMEAC DVYTRQCSTL LNTIELATMG ATFAAAGVNP VTKKQVLTAS NTPFILAEMT
     MEGMYGSSGD WAYTVGLPGK SGVGGGILAV VPGVMGIAAF SPPLDPVGNS VRGQKMVASV
     AQQLEYNLYK GSL
//
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