GenomeNet

Database: UniProt/TrEMBL
Entry: A1SKX0_NOCSJ
LinkDB: A1SKX0_NOCSJ
Original site: A1SKX0_NOCSJ 
ID   A1SKX0_NOCSJ            Unreviewed;       402 AA.
AC   A1SKX0;
DT   06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2007, sequence version 1.
DT   11-JUN-2014, entry version 60.
DE   RecName: Full=Acetate kinase;
DE            EC=2.7.2.1;
DE   AltName: Full=Acetokinase;
GN   Name=ackA; OrderedLocusNames=Noca_2953;
OS   Nocardioides sp. (strain BAA-499 / JS614).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Propionibacterineae; Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=196162;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BAA-499 / JS614;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Thompson L.S., Brettin T., Bruce D., Han C., Tapia R.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA   Mattes T., Gossett J., Richardson P.;
RT   "Complete sequence of chromosome 1 of Nocardioides sp. JS614.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the formation of acetyl phosphate from acetate
CC       and ATP. Can also catalyze the reverse reaction (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + acetate = ADP + acetyl phosphate.
CC   -!- COFACTOR: Mg(2+). Can also accept Mn(2+) (By similarity).
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA
CC       biosynthesis; acetyl-CoA from acetate: step 1/2.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the acetokinase family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000509; ABL82455.1; -; Genomic_DNA.
DR   RefSeq; YP_924142.1; NC_008699.1.
DR   ProteinModelPortal; A1SKX0; -.
DR   STRING; 196162.Noca_2953; -.
DR   EnsemblBacteria; ABL82455; ABL82455; Noca_2953.
DR   GeneID; 4595737; -.
DR   KEGG; nca:Noca_2953; -.
DR   PATRIC; 22747967; VBINocSp122728_3218.
DR   eggNOG; COG0282; -.
DR   HOGENOM; HOG000288399; -.
DR   KO; K00925; -.
DR   OMA; KYVTQRA; -.
DR   OrthoDB; EOG69975F; -.
DR   BioCyc; NSP196162:GH4V-2997-MONOMER; -.
DR   UniPathway; UPA00340; UER00458.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008776; F:acetate kinase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006085; P:acetyl-CoA biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006082; P:organic acid metabolic process; IEA:InterPro.
DR   HAMAP; MF_00020; Acetate_kinase; 1.
DR   InterPro; IPR004372; Ac/Proprionate_kinase.
DR   InterPro; IPR000890; Aliphatic_acid_kin_short-chain.
DR   InterPro; IPR023865; Aliphatic_acid_kinase_CS.
DR   PANTHER; PTHR21060; PTHR21060; 1.
DR   Pfam; PF00871; Acetate_kinase; 1.
DR   PIRSF; PIRSF000722; Acetate_prop_kin; 1.
DR   PRINTS; PR00471; ACETATEKNASE.
DR   TIGRFAMs; TIGR00016; ackA; 1.
DR   PROSITE; PS01075; ACETATE_KINASE_1; 1.
DR   PROSITE; PS01076; ACETATE_KINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Kinase; Magnesium;
KW   Metal-binding; Nucleotide-binding; Transferase.
FT   NP_BIND     211    215       ATP (By similarity){EA11}.
FT   NP_BIND     285    287       ATP (By similarity){EA11}.
FT   NP_BIND     333    337       ATP (By similarity){EA11}.
FT   ACT_SITE    151    151       Proton donor/acceptor (By
FT                                similarity){EA11}.
FT   METAL         9      9       Magnesium (By similarity){EA11}.
FT   METAL       387    387       Magnesium (By similarity){EA11}.
FT   BINDING      16     16       ATP (By similarity){EA11}.
FT   BINDING      94     94       Substrate (By similarity){EA11}.
FT   SITE        183    183       Transition state stabilizer (By
FT                                similarity).
FT   SITE        244    244       Transition state stabilizer (By
FT                                similarity).
SQ   SEQUENCE   402 AA;  42856 MW;  D0A263F9AEEA4633 CRC64;
     MSALVLVINA GSSSLKYSLI DAESGASHAV GLAERIADSS GAGGSLSHTG PDGVKHRSEL
     PLPSHEAALR AALDAFAAHG PSLEDATITA VGHRMVHGGE RFSEPALVDD ALVDAVRELV
     PLAPLHNPAN LEALGVARRL FDTLPHVAVF DTAFHQTLPE QAYTYAVPHE WREEHGIRRY
     GFHGTSHKFV SGETARLLGR PVEDTNTIVL HLGNGASATA VAGGRSVDTS MGLTPLEGLV
     MGTRSGDVDP ALHAHLHRQL GWSLEEIDQR LNRNSGIKGL LGFSDFRELG RLLEEGEPRA
     RLAMDVYCYR LRKYVGAYYA VLGRVDAIAF TGGVGEHVPD VRAQALAGLE RLGIRIDAEA
     NRGGHSGAFT VSAEDSEVAV LVVPTNEEWQ IARESLDVVR GG
//
DBGET integrated database retrieval system