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Database: UniProt/TrEMBL
Entry: A2W897_9BURK
LinkDB: A2W897_9BURK
Original site: A2W897_9BURK 
ID   A2W897_9BURK            Unreviewed;      1012 AA.
AC   A2W897; A0A0D5J1E1;
DT   20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   20-MAR-2007, sequence version 1.
DT   27-SEP-2017, entry version 57.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00635171};
DE            Short=PEPC {ECO:0000256|HAMAP-Rule:MF_00595};
DE            Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_00595};
DE            EC=4.1.1.31 {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00635171};
GN   Name=ppc {ECO:0000256|HAMAP-Rule:MF_00595};
GN   ORFNames=AK34_659 {ECO:0000313|EMBL:AJY12284.1}, BDAG_00900
GN   {ECO:0000313|EMBL:EAY68193.1};
OS   Burkholderia dolosa AU0158.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=350701 {ECO:0000313|EMBL:EAY68193.1, ECO:0000313|Proteomes:UP000053482};
RN   [1] {ECO:0000313|EMBL:EAY68193.1, ECO:0000313|Proteomes:UP000053482}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AU0158 {ECO:0000313|EMBL:EAY68193.1,
RC   ECO:0000313|Proteomes:UP000053482};
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B., Lander E., Galagan J., Devon K., Nusbaum C., Borowsky M.L.,
RA   Jaffe D., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA   Mauceli E., Brockman W., Young S., LaButti K., DeCaprio D.,
RA   Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M.,
RA   Howarth C., White J., Larson L., Alvarado L., Kodira C., Zeng Q.,
RA   Yandava C., Oleary S., LiPuma J., Lory S.;
RT   "The Genome Sequence of Burkholderia dolosa (strain AU0158).";
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AJY12284.1, ECO:0000313|Proteomes:UP000032886}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AU0158 {ECO:0000313|EMBL:AJY12284.1,
RC   ECO:0000313|Proteomes:UP000032886};
RX   PubMed=25931592;
RA   Johnson S.L., Bishop-Lilly K.A., Ladner J.T., Daligault H.,
RA   Jaissle J., Frey K.G., Koroleva G.I., Bruce D.C., Coyne S.R.,
RA   Broomall S.M., Li P., Teshima H., Gibbons H.S., Palacios G.F.,
RA   Rosenzweig C.N., McMurry K., Redden C.L., Xu Y., Currie B., Mayo M.,
RA   Minogue T.D., Chain P.S.;
RT   "Complete genome sequences for 59 burkholderia isolates, both
RT   pathogenic and near neighbor.";
RL   Genome Announc. 3:0-0(2015).
CC   -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid
CC       source for the tricarboxylic acid cycle. {ECO:0000256|HAMAP-
CC       Rule:MF_00595}.
CC   -!- CATALYTIC ACTIVITY: Phosphate + oxaloacetate = H(2)O +
CC       phosphoenolpyruvate + HCO(3)(-). {ECO:0000256|HAMAP-Rule:MF_00595,
CC       ECO:0000256|SAAS:SAAS00635165}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00595, ECO:0000256|SAAS:SAAS00635164};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00595}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC       {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00635168}.
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DR   EMBL; CP009795; AJY12284.1; -; Genomic_DNA.
DR   EMBL; CH482380; EAY68193.1; -; Genomic_DNA.
DR   RefSeq; WP_006763681.1; NZ_CP009795.1.
DR   STRING; 350701.BDAG_00900; -.
DR   EnsemblBacteria; AJY12284; AJY12284; AK34_659.
DR   EnsemblBacteria; EAY68193; EAY68193; BDAG_00900.
DR   KEGG; bdl:AK34_659; -.
DR   PATRIC; fig|350701.8.peg.736; -.
DR   eggNOG; ENOG4105CCA; Bacteria.
DR   eggNOG; COG2352; LUCA.
DR   KO; K01595; -.
DR   Proteomes; UP000032886; Chromosome 1.
DR   Proteomes; UP000053482; Unassembled WGS sequence.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; SSF51621; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation {ECO:0000256|HAMAP-Rule:MF_00595,
KW   ECO:0000256|SAAS:SAAS00635173};
KW   Complete proteome {ECO:0000313|Proteomes:UP000032886,
KW   ECO:0000313|Proteomes:UP000053482};
KW   Lyase {ECO:0000256|HAMAP-Rule:MF_00595,
KW   ECO:0000256|SAAS:SAAS00635169};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_00595,
KW   ECO:0000256|SAAS:SAAS00635157};
KW   Pyruvate {ECO:0000313|EMBL:EAY68193.1}.
FT   ACT_SITE    222    222       {ECO:0000256|HAMAP-Rule:MF_00595,
FT                                ECO:0000256|PROSITE-ProRule:PRU10111}.
FT   ACT_SITE    664    664       {ECO:0000256|HAMAP-Rule:MF_00595,
FT                                ECO:0000256|PROSITE-ProRule:PRU10112}.
SQ   SEQUENCE   1012 AA;  111036 MW;  A9C1CB50F6A256E4 CRC64;
     MKSSGSARTA RRNAALPPSD AQTGTVAAAA NGRAKPANQP ATKPKDPIRP TKRTATAAGT
     AVRAAARTAA APKSGARTRE DKDRPLFEDI RFLGRLLGDV VREQEGDTVF DVVETIRQTA
     VKFRREDDNE AAQTLEKKLR KLTPEQTVSV VRAFSYFSHL ANIAEDRHHN RRRRIHALAG
     SAPQPGTVAY ALEQLKTTGN ASKRLLQRFF DDALIVPVLT AHPTEVQRKS ILDAQHDIAR
     LLAERDQPLT ARERAHNEAM LRARVTALWQ TRMLRDARLT VGDEIENALS YYRATFLDEL
     PALYGDIEAA LAEHGLPARV PAFFQMGSWI GGDRDGNPNV TAATLDEAIN RQAAVILEHY
     LEQVHKLGAE LSVSNLLVGA SDAVKALAAA SPDQSPHRVD EPYRRALIGI YTRLAASARV
     RLGEGTVPVR SAGRGAPPVR ATPYADADEF VADLKVLTAS LDEHHGASLA APRLAPLVRA
     AEVFGFHLAS IDLRQSSDVH EAVVAELFAR AGVEANYAAL AEEDKLRVLL AALADPRPLR
     SPYLEYSALA QSELGVFEKA RDVRAQFGAR AVRNYIISHT ETVSDLVEVL LLQKETGLLE
     GTLGTPGSHA KNALMVIPLF ETIPDLRDAS RIMREYFALP GVDTLIAHQG AEQEVMLGYS
     DSNKDGGFLT SNWELYRAEL ALVDLFRERK ITLRLFHGRG GTVGRGGGPT YQAILSQPPG
     TVNGQIRLTE QGEVIASKFA NPEIGRRNLE TVVAATLEAS LLLQSNAPAQ LPAFEAAMQT
     LSDAAMAAYR ALVYETPGFT DYFFSSTPIT EIAELNIGSR PASRKLQDPK NRRIEDLRAI
     PWGFSWGQCR LLLTGWYGFG SAVSAYLDGA HDEAERTKRL ALLKKMNKTW PFFSNLLSNM
     DMVLAKTDLA VASRYAQLVA DRKLRKHVFE RIVAEWERTS RALAEITGHD TRLATNPLLA
     RSIKNRFPYL DPLNHLQVEL IKRHRAGDTN ARLRRGIHLT INGIAAGLRN TG
//
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