ID   A4GZD1_KLEPN            Unreviewed;      2035 AA.
AC   A4GZD1;
DT   01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2007, sequence version 1.
DT   03-APR-2013, entry version 40.
DE   SubName: Full=Yersiniabactin biosynthetic protein;
GN   Name=irp2;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NTUH-K2044;
RA   Lin T., Lee C., Hsieh P., Tsai S., Wang J.;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NTUH-K2044;
RX   PubMed=17981959; DOI=10.1128/JB.01219-07;
RA   Lin T.-L., Lee C.-Z., Hsieh P.-F., Tsai S.-F., Wang J.-T.;
RT   "Characterization of integrative and conjugative element ICEKp1-
RT   associated genomic heterogeneity in a Klebsiella pneumoniae strain
RT   isolated from a primary liver abscess.";
RL   J. Bacteriol. 190:515-526(2008).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AB298504; BAF49461.1; -; Genomic_DNA.
DR   RefSeq; YP_002920248.1; NC_012731.1.
DR   ProteinModelPortal; A4GZD1; -.
DR   STRING; 484021.KP1_3588; -.
DR   GeneID; 7949039; -.
DR   KEGG; kpu:KP1_3588; -.
DR   PATRIC; 20450695; VBIKlePne21779_3147.
DR   KO; K04784; -.
DR   ProtClustDB; CLSK889021; -.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 1.10.1200.10; -; 3.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR009081; Acyl_carrier_prot-like.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR013217; Methyltransf_12.
DR   InterPro; IPR013624; NRPS.
DR   InterPro; IPR006162; PPantetheine_attach_site.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF00668; Condensation; 2.
DR   Pfam; PF08242; Methyltransf_12; 1.
DR   Pfam; PF08415; NRPS; 2.
DR   Pfam; PF00550; PP-binding; 3.
DR   SUPFAM; SSF47336; ACP_like; 3.
DR   TIGRFAMs; TIGR01733; AA-adenyl-dom; 1.
DR   PROSITE; PS50075; ACP_DOMAIN; 3.
DR   PROSITE; PS00455; AMP_BINDING; 1.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   4: Predicted;
KW   Phosphopantetheine.
SQ   SEQUENCE   2035 AA;  228752 MW;  98FCF7EDDAA04992 CRC64;
     MISGAPSQDS LLPDNRHAAD YQQLRERLIQ ELNLTPQQLH EESNLIQAGL DSIRLMRWLH
     WFRKNGYRLT LRELYAAPTL AAWNQLMLSR SPENAEEETP PDESSWPNMT ESTPFPLTPV
     QHAYLTGRMP GQTLGGVGCH LYQEFEGHCL TASQLEQAIT TLLQRHPMLH IAFRPDGQQV
     WLPQPYWNGV TVHDLRHNDA ESRQAYLDAL RQRLSHRLLR VEIGETFDFQ LTLLPDNRHR
     LHVNIDLLIM DASSFTLFFD ELNALLAGES LPAIDTRYDF RSYLLHQQKI NQPLRDDARA
     YWLAKASTLP PAPVLPLACE PATLREVRNT RRRMIVPATR WHAFSNRAGE YGVTPTMALA
     TCFSAVLARW GGLTRLLLNI TLFDRQPLHP AVGAMLADFT NILLLDTACD GDTVSNLARK
     NQLTFTEDWE HRHWSGVELL RELKRQQRYP HGAPVVFTSN LGRSLYSSRA ESPLGEPEWG
     ISQTPQVWID HLAFEHHGEV WLQWDSNDAL FPPALVETLF DAYCQLINQL CDDESAWQKP
     FADMMPASQR AIRERVNATG APIPEGLLHE GIFRIALQQP QALAVTDMRY QWNYHELTDY
     ARRCAGRLIE CGVQPGDNVA ITMSKGAGQL VAVLAVLLAG AVYVPVSLDQ PAARREKIYA
     DASVRLVLIC QHDASAGSDD IPVLAWQQAI EAEPIANPVV RAPTQPAYII YTSGSTGTPK
     GVVISHRGAL NTCCDINTRY QVGPHDRVLA LSALHFDLSV YDIFGVLRAG GALVMVMENQ
     RRDPHAWCEL IQRHQVTLWN SVPALFDMLL TWCEGFADAT PENLRAVMLS GDWIGLDLPA
     RYRAFRPQGQ FIAMGGATEA SIWSNACEIH DVPAHWRSIP YGFPLTNQRY RVVDEQGRDC
     PDWVPGELWI GGIGVAEGYF NDPLRSEQQF LTLPDERWYR TGDLGCYWPD GTIEFLGRRD
     KQVKVGGYRI ELGEIESALS QLAGVKQATV LAIGEKEKTL AAYVVPQGEA FCVTDHRNPA
     LPQAWHTLAG TLPCCAISPE ISAEQVADFL QHRLLKLKPG HTAGADPLPL MNSLAIQPRW
     QAVVERWLAF LVTQRRLKPA AEGYQVCAGE EREDEHPHFS GHDLTLSQIL RGARNELSLL
     NDAQWSPESL AFNHPASAPY IQELATICQQ LAQRLQRPIR LLEVGTRTGR AAESLLAQLN
     AGQIEYVGLE QSQEMLLSAR QRLAPWPGTR LSLWNADTLA AHAHSADIIW LNNALHRLLP
     EDPGLLATLQ QLAVPGALLY VMEFRQLTPP ALLSTLLLTN GQPEALLHNS ADWAALFSAA
     AFNCQHGDEV AGLQRFLVQC PDRQVRRDPR QLQAALAGRL PGWMVPQRIV FLDALPLTAN
     GKIDYQALKR RHTPEAENPA EADLPQGDIE KQVAALWQQL LSTGNVTRET DFFQQGGDSL
     LATRLTGQLH QAGYEAQLSD LFNHPRLADF AATLRKTDVP VEQPFVHSPE DRYQPFALTD
     VQQAYLVGRQ PGFALGGVGS HFFVEFEIAD LDLTRLETVW NRLIARHDML RAIVRDGQQQ
     VLEQTPPWVI PAHTLHTPEE ALRVREKLAH QVLNPEVWPV FDLQVGYVDG MPARLWLCLD
     NLLLDGLSMQ ILLVELEHGY RYPQQLLPPL PVTFRDYLQQ PSLQSPNPDS LAWWQAQLDD
     IPPAPALPLR CLPQEVETPR FARLNGALDS TRWHRLKKRA ADAHLTPSAV LLSVWSTVLS
     AWSAQPEFTL NLTLFDRRPL HPQINQILGD FTSLMLLSWH PGESWLHSAQ SLQQRLSQNL
     NHRDVSAIRV MRQLAQRQNV PAVPMPVVFT SALGFEQDNF LARRNLLKPV WGISQTPQVW
     LDHQIYESEG ELRFNWDFVA ALFPVGQVER QFEQYCALLN RMAEDESGWQ LPLAALVPPV
     KHAGQCAERS PRVCPEQSQP HIAADESTVS LICDAFREVV GESVTPAENF FEAGATSLNL
     VQLHVLLQRH EFSTLTLLDL FTHPSPAALA DYLAGVATVE KTKRPRPVRR RQRRI
//

ID   C4XAM3_KLEPN            Unreviewed;      2035 AA.
AC   C4XAM3;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   03-APR-2013, entry version 30.
DE   SubName: Full=Yersiniabactin biosynthetic protein;
GN   Name=irp2; ORFNames=KP1_3588;
OS   Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Klebsiella.
OX   NCBI_TaxID=484021;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NTUH-K2044;
RA   Wu K.M., Tsai S.F.;
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NTUH-K2044;
RX   PubMed=19447910; DOI=10.1128/JB.00315-09;
RA   Wu K.-M., Li L.-H., Yan J.-J., Tsao N., Liao T.-L., Tsai H.-C.,
RA   Fung C.-P., Chen H.-J., Liu Y.-M., Wang J.-T., Fang C.-T.,
RA   Chang S.-C., Shu H.-Y., Liu T.-T., Chen Y.-T., Shiau Y.-R.,
RA   Lauderdale T.-L., Su I.-J., Kirby R., Tsai S.-F.;
RT   "Genome sequencing and comparative analysis of Klebsiella pneumoniae
RT   NTUH-K2044, a strain causing liver abscess and meningitis.";
RL   J. Bacteriol. 191:4492-4501(2009).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AP006725; BAH64181.1; -; Genomic_DNA.
DR   RefSeq; YP_002920248.1; NC_012731.1.
DR   ProteinModelPortal; C4XAM3; -.
DR   EnsemblBacteria; BAH64181; BAH64181; KP1_3588.
DR   GeneID; 7949039; -.
DR   KEGG; kpu:KP1_3588; -.
DR   PATRIC; 20450695; VBIKlePne21779_3147.
DR   eggNOG; COG3433; -.
DR   KO; K04784; -.
DR   ProtClustDB; CLSK889021; -.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 1.10.1200.10; -; 3.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR009081; Acyl_carrier_prot-like.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR013217; Methyltransf_12.
DR   InterPro; IPR013624; NRPS.
DR   InterPro; IPR006162; PPantetheine_attach_site.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF00668; Condensation; 2.
DR   Pfam; PF08242; Methyltransf_12; 1.
DR   Pfam; PF08415; NRPS; 2.
DR   Pfam; PF00550; PP-binding; 3.
DR   SUPFAM; SSF47336; ACP_like; 3.
DR   TIGRFAMs; TIGR01733; AA-adenyl-dom; 1.
DR   PROSITE; PS50075; ACP_DOMAIN; 3.
DR   PROSITE; PS00455; AMP_BINDING; 1.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   4: Predicted;
KW   Phosphopantetheine.
SQ   SEQUENCE   2035 AA;  228752 MW;  98FCF7EDDAA04992 CRC64;
     MISGAPSQDS LLPDNRHAAD YQQLRERLIQ ELNLTPQQLH EESNLIQAGL DSIRLMRWLH
     WFRKNGYRLT LRELYAAPTL AAWNQLMLSR SPENAEEETP PDESSWPNMT ESTPFPLTPV
     QHAYLTGRMP GQTLGGVGCH LYQEFEGHCL TASQLEQAIT TLLQRHPMLH IAFRPDGQQV
     WLPQPYWNGV TVHDLRHNDA ESRQAYLDAL RQRLSHRLLR VEIGETFDFQ LTLLPDNRHR
     LHVNIDLLIM DASSFTLFFD ELNALLAGES LPAIDTRYDF RSYLLHQQKI NQPLRDDARA
     YWLAKASTLP PAPVLPLACE PATLREVRNT RRRMIVPATR WHAFSNRAGE YGVTPTMALA
     TCFSAVLARW GGLTRLLLNI TLFDRQPLHP AVGAMLADFT NILLLDTACD GDTVSNLARK
     NQLTFTEDWE HRHWSGVELL RELKRQQRYP HGAPVVFTSN LGRSLYSSRA ESPLGEPEWG
     ISQTPQVWID HLAFEHHGEV WLQWDSNDAL FPPALVETLF DAYCQLINQL CDDESAWQKP
     FADMMPASQR AIRERVNATG APIPEGLLHE GIFRIALQQP QALAVTDMRY QWNYHELTDY
     ARRCAGRLIE CGVQPGDNVA ITMSKGAGQL VAVLAVLLAG AVYVPVSLDQ PAARREKIYA
     DASVRLVLIC QHDASAGSDD IPVLAWQQAI EAEPIANPVV RAPTQPAYII YTSGSTGTPK
     GVVISHRGAL NTCCDINTRY QVGPHDRVLA LSALHFDLSV YDIFGVLRAG GALVMVMENQ
     RRDPHAWCEL IQRHQVTLWN SVPALFDMLL TWCEGFADAT PENLRAVMLS GDWIGLDLPA
     RYRAFRPQGQ FIAMGGATEA SIWSNACEIH DVPAHWRSIP YGFPLTNQRY RVVDEQGRDC
     PDWVPGELWI GGIGVAEGYF NDPLRSEQQF LTLPDERWYR TGDLGCYWPD GTIEFLGRRD
     KQVKVGGYRI ELGEIESALS QLAGVKQATV LAIGEKEKTL AAYVVPQGEA FCVTDHRNPA
     LPQAWHTLAG TLPCCAISPE ISAEQVADFL QHRLLKLKPG HTAGADPLPL MNSLAIQPRW
     QAVVERWLAF LVTQRRLKPA AEGYQVCAGE EREDEHPHFS GHDLTLSQIL RGARNELSLL
     NDAQWSPESL AFNHPASAPY IQELATICQQ LAQRLQRPIR LLEVGTRTGR AAESLLAQLN
     AGQIEYVGLE QSQEMLLSAR QRLAPWPGTR LSLWNADTLA AHAHSADIIW LNNALHRLLP
     EDPGLLATLQ QLAVPGALLY VMEFRQLTPP ALLSTLLLTN GQPEALLHNS ADWAALFSAA
     AFNCQHGDEV AGLQRFLVQC PDRQVRRDPR QLQAALAGRL PGWMVPQRIV FLDALPLTAN
     GKIDYQALKR RHTPEAENPA EADLPQGDIE KQVAALWQQL LSTGNVTRET DFFQQGGDSL
     LATRLTGQLH QAGYEAQLSD LFNHPRLADF AATLRKTDVP VEQPFVHSPE DRYQPFALTD
     VQQAYLVGRQ PGFALGGVGS HFFVEFEIAD LDLTRLETVW NRLIARHDML RAIVRDGQQQ
     VLEQTPPWVI PAHTLHTPEE ALRVREKLAH QVLNPEVWPV FDLQVGYVDG MPARLWLCLD
     NLLLDGLSMQ ILLVELEHGY RYPQQLLPPL PVTFRDYLQQ PSLQSPNPDS LAWWQAQLDD
     IPPAPALPLR CLPQEVETPR FARLNGALDS TRWHRLKKRA ADAHLTPSAV LLSVWSTVLS
     AWSAQPEFTL NLTLFDRRPL HPQINQILGD FTSLMLLSWH PGESWLHSAQ SLQQRLSQNL
     NHRDVSAIRV MRQLAQRQNV PAVPMPVVFT SALGFEQDNF LARRNLLKPV WGISQTPQVW
     LDHQIYESEG ELRFNWDFVA ALFPVGQVER QFEQYCALLN RMAEDESGWQ LPLAALVPPV
     KHAGQCAERS PRVCPEQSQP HIAADESTVS LICDAFREVV GESVTPAENF FEAGATSLNL
     VQLHVLLQRH EFSTLTLLDL FTHPSPAALA DYLAGVATVE KTKRPRPVRR RQRRI
//