GenomeNet

Database: UniProt/TrEMBL
Entry: A4YKT4_BRASO
LinkDB: A4YKT4_BRASO
Original site: A4YKT4_BRASO 
ID   A4YKT4_BRASO            Unreviewed;       418 AA.
AC   A4YKT4;
DT   29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2007, sequence version 1.
DT   07-JUN-2017, entry version 66.
DE   RecName: Full=Aspartokinase {ECO:0000256|RuleBase:RU003448};
DE            EC=2.7.2.4 {ECO:0000256|RuleBase:RU003448};
GN   Name=lysC {ECO:0000313|EMBL:CAL74510.1};
GN   OrderedLocusNames=BRADO0574 {ECO:0000313|EMBL:CAL74510.1};
OS   Bradyrhizobium sp. (strain ORS 278).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium.
OX   NCBI_TaxID=114615 {ECO:0000313|EMBL:CAL74510.1, ECO:0000313|Proteomes:UP000001994};
RN   [1] {ECO:0000313|EMBL:CAL74510.1, ECO:0000313|Proteomes:UP000001994}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ORS 278 {ECO:0000313|Proteomes:UP000001994};
RX   PubMed=17540897; DOI=10.1126/science.1139548;
RA   Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.C.,
RA   Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L.,
RA   Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S.,
RA   Rouy Z., Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.S.,
RA   Saunders E., Bruce D., Richardson P., Normand P., Dreyfus B.,
RA   Pignol D., Stacey G., Emerich D., Vermeglio A., Medigue C.,
RA   Sadowsky M.;
RT   "Legumes symbioses: absence of nod genes in photosynthetic
RT   bradyrhizobia.";
RL   Science 316:1307-1312(2007).
CC   -!- CATALYTIC ACTIVITY: ATP + L-aspartate = ADP + 4-phospho-L-
CC       aspartate. {ECO:0000256|RuleBase:RU003448}.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC       pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.
CC       {ECO:0000256|RuleBase:RU004249}.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via de
CC       novo pathway; L-homoserine from L-aspartate: step 1/3.
CC       {ECO:0000256|RuleBase:RU004249}.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-threonine biosynthesis; L-
CC       threonine from L-aspartate: step 1/5.
CC       {ECO:0000256|RuleBase:RU004249}.
CC   -!- SIMILARITY: Belongs to the aspartokinase family.
CC       {ECO:0000256|RuleBase:RU003448}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CU234118; CAL74510.1; -; Genomic_DNA.
DR   RefSeq; WP_011923780.1; NC_009445.1.
DR   ProteinModelPortal; A4YKT4; -.
DR   STRING; 114615.BRADO0574; -.
DR   EnsemblBacteria; CAL74510; CAL74510; BRADO0574.
DR   KEGG; bra:BRADO0574; -.
DR   eggNOG; ENOG4105CFH; Bacteria.
DR   eggNOG; COG0527; LUCA.
DR   HOGENOM; HOG000293093; -.
DR   KO; K00928; -.
DR   OMA; INIMMIS; -.
DR   OrthoDB; POG091H0223; -.
DR   UniPathway; UPA00034; UER00015.
DR   UniPathway; UPA00050; UER00461.
DR   UniPathway; UPA00051; UER00462.
DR   Proteomes; UP000001994; Chromosome.
DR   GO; GO:0016597; F:amino acid binding; IEA:InterPro.
DR   GO; GO:0004072; F:aspartate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009089; P:lysine biosynthetic process via diaminopimelate; IEA:UniProtKB-UniPathway.
DR   GO; GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR   InterPro; IPR005260; Asp_kin_monofn.
DR   InterPro; IPR001341; Asp_kinase_dom.
DR   InterPro; IPR018042; Aspartate_kinase_CS.
DR   InterPro; IPR027795; GATS-like_ACT_dom.
DR   Pfam; PF00696; AA_kinase; 1.
DR   Pfam; PF01842; ACT; 1.
DR   Pfam; PF13840; ACT_7; 1.
DR   PIRSF; PIRSF000726; Asp_kin; 2.
DR   SUPFAM; SSF53633; SSF53633; 1.
DR   TIGRFAMs; TIGR00656; asp_kin_monofn; 1.
DR   TIGRFAMs; TIGR00657; asp_kinases; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00324; ASPARTOKINASE; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU004249};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001994};
KW   Kinase {ECO:0000256|RuleBase:RU003448, ECO:0000313|EMBL:CAL74510.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001994};
KW   Transferase {ECO:0000256|RuleBase:RU003448,
KW   ECO:0000313|EMBL:CAL74510.1}.
FT   DOMAIN      276    360       ACT. {ECO:0000259|PROSITE:PS51671}.
SQ   SEQUENCE   418 AA;  44902 MW;  73EC282083EC6732 CRC64;
     MGRLVLKFGG TSVANIDRIR NVARHVKREV DAGHEVAVVV SAMSGKTNEL VAWCTEASPM
     HDAREYDAVV ASGEQVTSGL LAIVLQSMGI QARSWQGWQI PIKTSDAHAS ARIVGIDGSE
     LIQRFQERKE VAVIAGFQGI NAETGRITTL GRGGSDTSAV AIAAAIKADR CDIYTDVDGV
     YTTDPRVVPK AKRLDKIAFE DMLELASQGA KVLQVRSVEL GMVHNMPIFV RSSFDKPEDI
     DPHANQPPGT LICSEEQIME NHVVTGIAFS KDEAQISVRQ IEDKPGIAAS IFGPLADANI
     NVDMIVQNVS EDGKTTDLTF TVPATDYNRA RETITAAKDK IGYQRMDAAT DVAKVSVIGS
     GMRSHAGVAA KGFAALAARN INIRAITTSE IKFSVLIDAA YTELAVRTLH TLYGLDQA
//
DBGET integrated database retrieval system