ID   A7ARX3_BABBO            Unreviewed;      4097 AA.
AC   A7ARX3;
DT   11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT   11-SEP-2007, sequence version 1.
DT   06-FEB-2013, entry version 24.
DE   SubName: Full=Cytoplasmic dynein heavy chain, putative;
GN   ORFNames=BBOV_IV009380;
OS   Babesia bovis.
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC   Babesiidae; Babesia.
OX   NCBI_TaxID=5865;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T2Bo;
RX   PubMed=17953480; DOI=10.1371/journal.ppat.0030148;
RA   Brayton K.A., Lau A.O.T., Herndon D.R., Hannick L., Kappmeyer L.S.,
RA   Berens S.J., Bidwell S.L., Brown W.C., Crabtree J., Fadrosh D.,
RA   Feldblum T., Forberger H.A., Haas B.J., Howell J.M., Khouri H.,
RA   Koo H., Mann D.J., Norimine J., Paulsen I.T., Radune D., Ren Q.,
RA   Smith R.K. Jr., Suarez C.E., White O., Wortman J.R., Knowles D.P. Jr.,
RA   McElwain T.F., Nene V.M.;
RT   "Genome sequence of Babesia bovis and comparative analysis of
RT   apicomplexan hemoprotozoa.";
RL   PLoS Pathog. 3:1401-1413(2007).
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data.
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DR   EMBL; AAXT01000002; EDO07292.1; -; Genomic_DNA.
DR   RefSeq; XP_001610860.1; XM_001610810.1.
DR   ProteinModelPortal; A7ARX3; -.
DR   GeneID; 5479094; -.
DR   KEGG; bbo:BBOV_IV009380; -.
DR   EuPathDB; PiroplasmaDB:BBOV_IV009380; -.
DR   KO; K10413; -.
DR   GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   InterPro; IPR026983; DHC_fam.
DR   InterPro; IPR024743; Dynein_HC_stalk.
DR   InterPro; IPR004273; Dynein_heavy_dom.
DR   InterPro; IPR013602; Dynein_heavy_dom-2.
DR   PANTHER; PTHR10676; PTHR10676; 1.
DR   Pfam; PF08393; DHC_N2; 1.
DR   Pfam; PF03028; Dynein_heavy; 1.
DR   Pfam; PF12777; MT; 1.
PE   4: Predicted;
KW   Complete proteome; Reference proteome.
SQ   SEQUENCE   4097 AA;  470361 MW;  2F5D4E995CAFD99F CRC64;
     MNYKQEDNAI INDTIVGHVK YTDYVKFISQ VASLYLGVSQ HSVCESLLNN QTFVKNALLD
     SKGGKPLLVS ADALSTENEK WDIRTHRGWD DLFGTDRKAV AFIGLTCYGE KVIQEDDGLS
     KTMLPLFWNC NLSPCKLSLQ LLEDIINPIL MNEKYKYCGD NKRHDLVNDA LNSIMRTINI
     FRQIDSKSSI EPPYFVIGES LSRVVTYGGP NAKRWDIQIP SEAMLEDIKQ NVVQWSVEVA
     RILGLYHKML NNELSSATSS VNDVVDGDII SSETITSDSS SDTYSSFSDS DQFENSQRID
     MFDGDANVED SSTKLSMGFH IEKPINVEEE TTFWLHYEMA LMDLHEQLCS PLVENTISLL
     EYNNVDVKSI YSFDDAMETT SRMLDWVENI NIIMRSFPVG YLKGVGDVGV LKDGIYIVLK
     HLSKARFLKH YSSNKLSDII LGLTVEMLAS CAAIIGDGIN KAIDVELSRD LFKSIEEIMT
     IWNHGVEALK ADLDIDGNST VTFFTGECNN RISEARDVLQ AIEQSIHRYL SIYADAAIIV
     EMKIVFNGNL QHENIKYCEK IVDVINQSNS LCKSMLDSYS LNIKNKIQVN ESFDFNDILP
     CVHTFNFALT QIENTIMTTF RSCISDISNL DSIPQVLYYV TQFSSCEGGY LTDVFENVVN
     IIADEVEALE TITTMPNVNN VNPVYYITIS DSGAEAHNIA RIKGKLMVRN IRYLYILQVL
     EKIVKRLGLV VGSETIKNLI NKMGKLHENV NTLILQCSTE CGLQMCRKMI DITKGDVEEM
     QCVILYPFDN SLDNLGKWMY MAYFGMSVDY ESTAEMHTIL SIVLIVRHIF RSFNEIGELK
     AIYDKQNSTN ALYLPEPFSL AIQNMTWENL MIPDTLETVY NIVHSEFLDT SRSVALIGFL
     EDIKPIISTL TATQLLLTIL SYVKSIKSSE ETHVDYEESC DTKYIIDMVL LSIKTWNETK
     ANNITMQLEH ELYNNSRITV TFKEEDSLLH MDPTIETLKG DLYNDIAPKI NAPMYLLNEL
     SALCNVVDRE LENLFDCLID TIKRKIDSIL TNLDNDFQRH KNFINHWETH FIMLSNENAT
     TRRLVEELDK LEQGLLTNDN PVGPANMLIP ERIKYQQVKR LEMNLFQIVC NHALKESRNI
     LQQLSDIGMQ RDISPSNKTE TNLDKWQFEV SIQLPMKHTS SHWQIEDLIK SDEFKKLLAC
     MTEQPFEPTD AKSILNTYVD YCIRLDPFLI SLYNAFAKND KLTSQQAAWT SHADAISTLE
     NICKEKSLDP PNGWIYSATI KENVELLFDN ADQHLDEVML EDLKPISQLP VVYEKLEHLL
     DLTWQKTKDK IDQGYIDHND ILCTIEHIAE TENLLGRQDL AVRELLVQFS FELHLTTNTE
     RFIQLSDYKT QWGNAKVFLN EYDKILEQDT KTTTKQNIVD RLTYVDEGLN KLNSVCKVMK
     NKVNKIYSLL NGTIGTYLNN DDFILRLKDY LSNFKSPDIK LEESITINQW LLIHDTCSEA
     VNFVLKSYEF NKMVRDWIET LSEKYDTMEL PCIENTIPLW DVPHDGSIEI PHWKNINSTS
     IMYAIDDSLA ILNTYISSIY AEELKGDINE WITTLSGAKI EIERWKNTET QLQYLYNLFR
     SSTVRKKLAN EAQLLNCILK EYNMITVSLT YVNDLSRCEE KLSEIANSIK DLEDRLGIYL
     DEQRFICPRY FFLRDDELFH IIGMVNIDEM KSNISKMFPG IFALECNDGS ITGIKSKDGD
     SLPLDENIIY ETVEPYKVLM DMHTSIKNSI RSQILRCHEE FTPIYCNEKM NPDAFWGCFS
     RYVSQALVVS LSVSWTRCME STKSSNEATN LHILLNKMID ILSKPPQTYI SQRKKMEKIS
     IVLIYQLQKS KLLPLQNLES WDWQRCIRYY INRKNDVELH IGHKVHIYGY EFMGVGPPMI
     ITPLTETCLI SISEAMDNCL IPNPQGPAGT GKTESIKVLA ELCGHPFWIF NCSEGFDSIS
     MERIFAGLCQ MGAWGIFDEF NRLIDGVLSS IAEKIQQMIK CKKGNIGDIT LVNRKILLDK
     NVGIFITINP GYISRRQFPL NLRKLCRPII MENVDLKQII HAMLMLNGIS DSSLVSKTLW
     DILHCCRICF GELIYDFGLR CSKSILLHIS MNLHRDNNKN PYSVYSIIDY LKTALSTVIL
     PRLLSNEKCV LNTVVVGCLP KHIAQPDLIH QTSDDQHDAF VKLFDSQYET LSEVPNLKEK
     CSTLFSLMKL TKGIILYGPS GSGKTLCLSA TVNIMRQING GNYDVIRFDP NAIDPNELYG
     NDNNGSWQEG LFSYTLRQYS CSPRNLIIIF DGDIYSSWVE NMNSLLDDNL VLTLTNGHRI
     PLTPNVTILF ETHSLQHVTL ATTSRCSLIR FEIKESYLCI PEYKSYFDFL DTDIRLHRYH
     LFKALYLSSH DYVNFIFSFA LSYGSYMGKL EWQSFLDKID DISKPNEQRI VYTAAAGQIV
     GESNNSELHI IVKTLLLHGN SAVFTSTQNS DLSVIIGNIV SSIDGWFLVT MYLSKNAGRK
     AIMKVLQKHT VITLIGSNLT MLPIEKLDGA SRMVLLIEDI DCLTTEPTDL QCWSLIRELV
     EFKALFTKNE TDNWTKVHLK DISIFLATKQ PSPNLIPQRL RKSLPVINIE LLLDCRNYTQ
     LTIPGTVDDT ESIEFDASQR DGFRDKLIYL NIDLSTIEHF SESFQTLRQF LQQKCNRLII
     MGCDMHLRKI LCEATSSFNG YKITCLDHTS WNSTMVNAFQ NAVFKCEKIC IYIDWDLLVL
     QSPEVACEMK HMIITGDYSS ILSTDVTDIC ENKAHLTDVE SSGQDIQRSV FGHIKYIIST
     KTQNVDASLI SKSMLLTLPH LSSNFKASVQ NALMPADFKF DMRKIYDIYV GKFRQKSSLS
     DFLVYIISTK DNIIDNKTAH MTEYKHFETG IKRINNAKSE IASMQTILDS QRTKLVEKNE
     EAKIKVDQIT KLKNEAKIKQ EKANEMKISL EKEKGVLIDR NKEIQHQLEA VAPLIEESQK
     EIESINRKSL DELRSMSNPP SIIKDTMEMV VLLLTNSTSS NIAWDICRKV IKSADFITKI
     VQFNTQALNP VTVSIVKERL KNPSWDKDRI SKASKAAGPL ARWVESILRY GEIALNVAPL
     LKEVELLKES NAKNEELLNA QSELIMNLEN DIDQYQVEYS DLVQSIADVK TEIENASLRL
     VRSEKIMSNL STEVGHWNNS IATLERNNDC IIGNAILVSS LLNLCGMMKS HDRKKFYKMV
     TDVLKQEEIN YSVDPSYLDD CTSRMIQSNM KYRHCIILDA TDMMYIKYID GDYKKVSACD
     EHFLSILYAS KKCNLTLVIT DIVYAHTNIK HVILDEVLNK GKGLKILFEI STDDIRRCEQ
     LKTEDDHYIQ NIFDLCYKLR LKMTEEHFNS FCLDILMKEI NPTLYNAHTD VIITQHEIKG
     KLHGKEDELL GILSTTEDIL ADNLSDYLDE YRNERDKLHD SLSECEKVVD RFNKFIMEHS
     DFTSLISSLY NTIKKLESIN SMYAFDVYML LHAMKNCHSR PLRNQVLIKV VYSWVCQSIF
     TDDLLNWTVD ILNIYYNQVD RCADINNLLE EISQPQSESS KLYQKIEHMR QIYLQYDDSL
     LFGIQTDIFD YYNLIIVVTK SFDDPTEFLY SYATSKGHEL KTLAMSTLAD MSCIISNIEV
     LLSEGYWVVL KNAHLMPSWF ERFECQFPNK SDSPKLFVTW DHTMSINRNI MLRRYRLIYQ
     GADSFQSTFH RLYQLYSHLF IDCDLIKSHL MMKAVLVHAI IICRQSYIPY GWTQMYLFDL
     NDLSLALNAT TRFLEIHYNE LNSYNGSILE FQQSSLLLKD WKTRIYEIYQ PKISHDLDCK
     ILYDIICFTD IGKYIIPLPS LNILEWIEMI PNDRTSSSLI GLPDFTETLM LESKFRKLRN
     FRMSSAAHIT QDTTCSNIAS YESLNIFDGQ MPLLDAALQR QWRKLPMKHD ERYIASEYNK
     LKTMFEQQVP VTVNFDVFAE PLEILDILRI QASISSGFDL DNLILTAGLF PVVSNLDITN
     IAKRTCNCKP INGKLLIDHL ELMGASYDCK THRICIPTET SVESREPTQV LVEWIRHTCN
     IKQETVLLPI YNSEGYV
//