ID A7S6C3_NEMVE Unreviewed; 108 AA.
AC A7S6C3;
DT 02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT 02-OCT-2007, sequence version 1.
DT 28-JUN-2023, entry version 62.
DE RecName: Full=Insulin-like domain-containing protein {ECO:0000259|SMART:SM00078};
GN ORFNames=NEMVEDRAFT_v1g207484 {ECO:0000313|EMBL:EDO40725.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO40725.1, ECO:0000313|Proteomes:UP000001593};
RN [1] {ECO:0000313|EMBL:EDO40725.1, ECO:0000313|Proteomes:UP000001593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SIMILARITY: Belongs to the insulin family.
CC {ECO:0000256|ARBA:ARBA00009034}.
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DR EMBL; DS469587; EDO40725.1; -; Genomic_DNA.
DR RefSeq; XP_001632788.1; XM_001632738.1.
DR AlphaFoldDB; A7S6C3; -.
DR EnsemblMetazoa; EDO40725; EDO40725; NEMVEDRAFT_v1g207484.
DR KEGG; nve:5512419; -.
DR HOGENOM; CLU_2200052_0_0_1; -.
DR InParanoid; A7S6C3; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR Gene3D; 1.10.100.10; Insulin-like; 1.
DR InterPro; IPR016179; Insulin-like.
DR InterPro; IPR036438; Insulin-like_sf.
DR InterPro; IPR022352; Insulin_family.
DR Pfam; PF00049; Insulin; 1.
DR PRINTS; PR00276; INSULINFAMLY.
DR SMART; SM00078; IlGF; 1.
DR SUPFAM; SSF56994; Insulin-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..108
FT /note="Insulin-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002714150"
FT DOMAIN 41..108
FT /note="Insulin-like"
FT /evidence="ECO:0000259|SMART:SM00078"
FT REGION 61..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 108 AA; 12096 MW; B181780CD9A12B50 CRC64;
MQNPSCCLVA MVILCVLLCV GLVQPEPHHK VREIGSSSTI GFFCGEQIIS AYFDVCGSRR
RKRSSPVTMD RQDAKQFVSR QKRSSPNANI VEECCGESCA FEEIREYC
//
