GenomeNet

Database: UniProt/TrEMBL
Entry: A7TPF5_VANPO
LinkDB: A7TPF5_VANPO
Original site: A7TPF5_VANPO 
ID   A7TPF5_VANPO            Unreviewed;       486 AA.
AC   A7TPF5;
DT   02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT   02-OCT-2007, sequence version 1.
DT   07-JUN-2017, entry version 59.
DE   RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE            EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN   ORFNames=Kpol_507p3 {ECO:0000313|EMBL:EDO15841.1};
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294)
OS   (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
OC   Vanderwaltozyma.
OX   NCBI_TaxID=436907 {ECO:0000313|Proteomes:UP000000267};
RN   [1] {ECO:0000313|EMBL:EDO15841.1, ECO:0000313|Proteomes:UP000000267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 {ECO:0000313|Proteomes:UP000000267};
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M.,
RA   Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two
RT   yeast species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- SIMILARITY: Belongs to the hexokinase family.
CC       {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672880}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; DS480442; EDO15841.1; -; Genomic_DNA.
DR   RefSeq; XP_001643699.1; XM_001643649.1.
DR   ProteinModelPortal; A7TPF5; -.
DR   STRING; 436907.XP_001643699.1; -.
DR   EnsemblFungi; EDO15841; EDO15841; Kpol_507p3.
DR   GeneID; 5543957; -.
DR   KEGG; vpo:Kpol_507p3; -.
DR   eggNOG; KOG1369; Eukaryota.
DR   eggNOG; COG5026; LUCA.
DR   InParanoid; A7TPF5; -.
DR   KO; K00844; -.
DR   OrthoDB; EOG092C2JW4; -.
DR   PhylomeDB; A7TPF5; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:EnsemblFungi.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR   GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001678; P:cellular glucose homeostasis; IEA:InterPro.
DR   GO; GO:0032445; P:fructose import; IEA:EnsemblFungi.
DR   GO; GO:0006000; P:fructose metabolic process; IEA:EnsemblFungi.
DR   GO; GO:0046323; P:glucose import; IEA:EnsemblFungi.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:EnsemblFungi.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:EnsemblFungi.
DR   InterPro; IPR001312; Hexokinase.
DR   InterPro; IPR019807; Hexokinase_BS.
DR   InterPro; IPR022673; Hexokinase_C.
DR   InterPro; IPR022672; Hexokinase_N.
DR   PANTHER; PTHR19443; PTHR19443; 1.
DR   Pfam; PF00349; Hexokinase_1; 1.
DR   Pfam; PF03727; Hexokinase_2; 1.
DR   PROSITE; PS00378; HEXOKINASE_1; 1.
DR   PROSITE; PS51748; HEXOKINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672869};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000267};
KW   Glycolysis {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672870};
KW   Kinase {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672871};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672883};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000267};
KW   Transferase {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672884}.
FT   DOMAIN       27    221       Hexokinase_1. {ECO:0000259|Pfam:PF00349}.
FT   DOMAIN      227    469       Hexokinase_2. {ECO:0000259|Pfam:PF03727}.
SQ   SEQUENCE   486 AA;  53480 MW;  6F564D02E1EB4CE3 CRC64;
     MVHLGPKKPP MRKGSMADVP KELLDQIADF EKIYDTPAPV LKAIVKHFTS ELDKGLSKKG
     GNIPMIPGWV MDYPTGKESG DYLAIDLGGT NLRVVLVKLG GDRTFDTTQS KYRLPDAMRT
     TQDPEELWEF IADSLEAFVN EQFPEGCTKP LPLGFTFSFP ASQDKINEGI LQRWTKGFDI
     PETEGKDVVK MLQKQLEKRN IPIRVVALIN DTTGTLVASL YTDGETKMGV IFGTGVNGAY
     YDVISGVEKL QGRLPADITA DTPMAINCEY GSFDNEHVVL PRNRHDIIID EESPRPGQQA
     FEKMSSGYYL GELLRLAILE MVDNGHILKG QDCSKLRKPY IMDTSFPSRI EDDPFENLEN
     TDELLSKTLG LSTTVQERKL IRRVSELIGT RSARIAACGI AGICQKRGYD TAHIAADGSV
     YNLYPGFKER AAAALRDIYD WKEDKPENYP IVIVPAEDGS GAGAAIIAAL TEKRLAAGKS
     VGVLGA
//
DBGET integrated database retrieval system