ID   A8BS30_GIAIC            Unreviewed;       707 AA.
AC   A8BS30;
DT   13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2007, sequence version 1.
DT   03-APR-2013, entry version 28.
DE   SubName: Full=Dual specificity phosphatase, catalytic;
GN   ORFNames=GL50803_15112;
OS   Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia
OS   lamblia).
OC   Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX   NCBI_TaxID=184922;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50803 / WB clone C6;
RX   PubMed=17901334; DOI=10.1126/science.1143837;
RA   Morrison H.G., McArthur A.G., Gillin F.D., Aley S.B., Adam R.D.,
RA   Olsen G.J., Best A.A., Cande W.Z., Chen F., Cipriano M.J.,
RA   Davids B.J., Dawson S.C., Elmendorf H.G., Hehl A.B., Holder M.E.,
RA   Huse S.M., Kim U.U., Lasek-Nesselquist E., Manning G., Nigam A.,
RA   Nixon J.E.J., Palm D., Passamaneck N.E., Prabhu A., Reich C.I.,
RA   Reiner D.S., Samuelson J., Svard S.G., Sogin M.L.;
RT   "Genomic minimalism in the early diverging intestinal parasite Giardia
RT   lamblia.";
RL   Science 317:1921-1926(2007).
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data.
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DR   EMBL; AACB02000039; EDO77463.1; -; Genomic_DNA.
DR   RefSeq; XP_001705137.1; XM_001705085.1.
DR   ProteinModelPortal; A8BS30; -.
DR   EnsemblProtists; EDO77463; EDO77463; GL50803_15112.
DR   GeneID; 5698036; -.
DR   KEGG; gla:GL50803_15112; -.
DR   EuPathDB; GiardiaDB:GL50803_15112; -.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IEA:GOC.
DR   InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR   InterPro; IPR020422; Dual-sp_phosphatase_subgr_cat.
DR   InterPro; IPR024950; DUSP.
DR   InterPro; IPR000387; Tyr/Dual-sp_Pase.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   PANTHER; PTHR10159; PTHR10159; 1.
DR   Pfam; PF00782; DSPc; 1.
DR   SMART; SM00195; DSPc; 1.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE   4: Predicted;
KW   Complete proteome; Hydrolase; Reference proteome.
SQ   SEQUENCE   707 AA;  78490 MW;  2E441038478C54F7 CRC64;
     MSDSSRINRS DTTSNDLLKA INVRLQGKSV HPWGSDQYSS QDLPRNINAA PPLLSVLNSE
     EVGLYRFFPS ELQVDTSVPL IKRAAPRINP KSDQESDILV STSTSIPHDD VVDGTNGSIT
     SDSSDDGELF RRPTPQAGTR SNSIASIPQS KPAPPSLKPV LPLTMPALNT DTSKEKLTLT
     LPLSSKGQPS PLESGLKRSR PMSMSEDKAL KIKQYDAIMS KITEFLYLSS LTAAQNTELL
     QKNKITHVIN CCLESQSPKY GVPNLACLLL KLRDTGLENI DSLFLEAIAF IHEARMQGKA
     VLVHCYQGVS RSASLVIAYI MWANDLSYEE AYSHVRSCRG VVAPNTGFVF RLVSWWRRRH
     SDLTTARIAA KYAEEHAVKG IISLEEGCNI DAAIQGIRGS HLIKCTPPEE LHSRPALYRL
     APYNDMMPDM IVLKPVDTVI KNGKPNFLLD ERFIYVAPLP CFIIIFIGAE VDTLHDSPEK
     RQYLNVALNR QLTLLRSYEG APSQTVKIFQ RQLRNACISI LKGEHSYKAT LTVPRSIMFR
     SSSTSLIQQR HNSNRVHTAL AVLRTSDFSA PKGHFLSQHK YNILDDYEGR FEMTYEKVVT
     YAAVALGMLG LIKVEPYDKD NHFEHTKSQI LGSSSTGGQS GLVHTSAQPQ ARVQVRTEIL
     YVEGLYEPTP VLYDLASAAL AITDTTIWSP LRTLDVDASI ISRLEKQ
//