ID   A9N7P7_SALPB            Unreviewed;       361 AA.
AC   A9N7P7;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   01-MAY-2013, entry version 38.
DE   RecName: Full=dTDP-glucose 4,6-dehydratase;
DE            EC=4.2.1.46;
GN   OrderedLocusNames=SPAB_00933;
OS   Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=1016998;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1250 / SPB7;
RG   The Salmonella enterica serovar Paratyphi B Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA   Fulton R., Cordes M., Wollam A., Shah N., Pepin K., Bhonagiri V.,
RA   Nash W., Johnson M., Thiruvilangam P., Wilson R.;
RL   Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-
CC       alpha-D-glucose + H(2)O.
CC   -!- COFACTOR: NAD (By similarity).
CC   -!- SIMILARITY: Belongs to the sugar epimerase family. dTDP-glucose
CC       dehydratase subfamily.
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DR   EMBL; CP000886; ABX66355.1; -; Genomic_DNA.
DR   RefSeq; YP_001587188.1; NC_010102.1.
DR   ProteinModelPortal; A9N7P7; -.
DR   SMR; A9N7P7; 1-361.
DR   STRING; 272994.SPAB_00933; -.
DR   EnsemblBacteria; ABX66355; ABX66355; SPAB_00933.
DR   GeneID; 5782812; -.
DR   KEGG; spq:SPAB_00933; -.
DR   PATRIC; 18529791; VBISalEnt120821_0780.
DR   eggNOG; COG1088; -.
DR   HOGENOM; HOG000168006; -.
DR   KO; K01710; -.
DR   OMA; AKKAFRF; -.
DR   ProtClustDB; PRK10084; -.
DR   BioCyc; SENT28901:GH9O-931-MONOMER; -.
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0008460; F:dTDP-glucose 4,6-dehydratase activity; IEA:EC.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0009225; P:nucleotide-sugar metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; -; 1.
DR   InterPro; IPR005888; dTDP_Gluc_deHydtase.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   PANTHER; PTHR10366:SF41; PTHR10366:SF41; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   TIGRFAMs; TIGR01181; dTDP_gluc_dehyt; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Lyase.
SQ   SEQUENCE   361 AA;  40747 MW;  ED074B400A7EBC52 CRC64;
     MKILITGGAG FIGSAVVRHI IKNTQDTVVN IDKLTYAGNL ESLSDISESN RYNFEHADIC
     DSAEITRIFE QYQPDAVMHL AAESHVDRSI TGPAAFIETN IVGTYVLLEV ARKYWSALGE
     DKKNNFRFHH ISTDEVYGDL PHPDEVENSV TLPLFTETTA YAPSSPYSAS KASSDHLVRA
     WRRTYGLPTI VTNCSNNYGP YHFPEKLIPL VILNALEGKP LPIYGKGDQI RDWLYVEDHA
     RALHMVVTEG KAGETYNIGG HNEKKNLDVV FTICDLLDEI VPKATSYREQ ITYVADRPGH
     DRRYAIDAGK ISRELGWKPL ETFESGIRKT VEWYLANTQW VNNVKSGAYQ SWIEQNYEGR
     Q
//