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Database: UniProt/TrEMBL
Entry: A9VSD2_BACWK
LinkDB: A9VSD2_BACWK
Original site: A9VSD2_BACWK 
ID   A9VSD2_BACWK            Unreviewed;       429 AA.
AC   A9VSD2;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   09-JUL-2014, entry version 50.
DE   RecName: Full=UDP-N-acetylglucosamine 1-carboxyvinyltransferase;
DE            EC=2.5.1.7;
DE   AltName: Full=Enoylpyruvate transferase;
DE   AltName: Full=UDP-N-acetylglucosamine enolpyruvyl transferase;
GN   Name=murA; OrderedLocusNames=BcerKBAB4_5132;
OS   Bacillus weihenstephanensis (strain KBAB4).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=315730;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KBAB4;
RX   PubMed=17434157; DOI=10.1016/j.cbi.2007.03.003;
RA   Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B.,
RA   Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.H.,
RA   Sanchis V., Nguen-The C., Lereclus D., Richardson P., Wincker P.,
RA   Weissenbach J., Ehrlich S.D., Sorokin A.;
RT   "Extending the Bacillus cereus group genomics to putative food-borne
RT   pathogens of different toxicity.";
RL   Chem. Biol. Interact. 171:236-249(2008).
CC   -!- FUNCTION: Cell wall formation. Adds enolpyruvyl to UDP-N-
CC       acetylglucosamine (By similarity).
CC   -!- CATALYTIC ACTIVITY: Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-
CC       glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-
CC       D-glucosamine.
CC   -!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the EPSP synthase family. MurA subfamily.
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DR   EMBL; CP000903; ABY46278.1; -; Genomic_DNA.
DR   RefSeq; YP_001647906.1; NC_010184.1.
DR   ProteinModelPortal; A9VSD2; -.
DR   STRING; 315730.BcerKBAB4_5132; -.
DR   EnsemblBacteria; ABY46278; ABY46278; BcerKBAB4_5132.
DR   GeneID; 5845373; -.
DR   KEGG; bwe:BcerKBAB4_5132; -.
DR   PATRIC; 19015019; VBIBacWei55973_5796.
DR   eggNOG; COG0766; -.
DR   HOGENOM; HOG000075602; -.
DR   KO; K00790; -.
DR   OMA; GATIWRE; -.
DR   OrthoDB; EOG68M4GK; -.
DR   BioCyc; BWEI315730:GHRU-5276-MONOMER; -.
DR   UniPathway; UPA00219; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008760; F:UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0019277; P:UDP-N-acetylgalactosamine biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.65.10.10; -; 2.
DR   HAMAP; MF_00111; MurA; 1.
DR   InterPro; IPR001986; Enolpyruvate_Tfrase_dom.
DR   InterPro; IPR013792; RNA3'P_cycl/enolpyr_Trfase_a/b.
DR   InterPro; IPR005750; UDP_GlcNAc_COvinyl_MurA.
DR   PANTHER; PTHR21090:SF4; PTHR21090:SF4; 1.
DR   Pfam; PF00275; EPSP_synthase; 1.
DR   SUPFAM; SSF55205; SSF55205; 1.
DR   TIGRFAMs; TIGR01072; murA; 1.
PE   1: Evidence at protein level;
KW   Cell cycle; Cell division; Cell shape;
KW   Cell wall biogenesis/degradation; Complete proteome; Cytoplasm;
KW   Peptidoglycan synthesis; Transferase.
FT   ACT_SITE    117    117       Proton donor (By similarity){EA15}.
FT   MOD_RES     117    117       2-(S-cysteinyl)pyruvic acid O-
FT                                phosphothioketal (By similarity){EA15}.
SQ   SEQUENCE   429 AA;  45923 MW;  C8C6DB85C836B536 CRC64;
     MEKLLIEGGR ALNGTIRVSG AKNSAVALIP ATILADTPVT IGGVPNISDV KMLGDLLEEI
     GGKVTYGQEE EMVVDPSNMV AMPLPNGKVK KLRASYYLMG AMLGRFKKAV IGLPGGCHLG
     PRPIDQHIKG FEALGAYVTN EQGAIYLRAD ELRGARIYLD VVSVGATINI MLVAVRAKGR
     TVIENAAKEP EIIDVATLLT SMGARIKGAG TDVIRIDGVD SLHGCHHTII PDRIEAGTYM
     ILGAASGGEV TVDNVIPQHL ESVTAKLREA GVQIETNDDQ ITVNGNRRLK VVDVKTLVYP
     GFPTDLQQPF TTLLTKAHGT GVVTDTIYSA RFKHIDELRR MNAQIKVEGR SAIVTGPVLL
     QGAKVKASDL RAGASLVIAG LMADGITEVT GLDHIDRGYE NIVDKLKGLG ANIWREQMTK
     QEIEEMKNA
//
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