ID A9WC77_CHLAA Unreviewed; 349 AA.
AC A9WC77;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 01-MAY-2013, entry version 39.
DE SubName: Full=Aspartate-semialdehyde dehydrogenase;
DE EC=1.2.1.11;
GN OrderedLocusNames=Caur_0217;
OS Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC Bacteria; Chloroflexi; Chloroflexales; Chloroflexaceae; Chloroflexus.
OX NCBI_TaxID=324602;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29366 / DSM 635 / J-10-fl;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O.,
RA Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Pierson B.K.,
RA Blankenship R.E., Richardson P.;
RT "Complete sequence of Chloroflexus aurantiacus J-10-fl.";
RL Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aspartate-semialdehyde dehydrogenase
CC family.
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DR EMBL; CP000909; ABY33470.1; -; Genomic_DNA.
DR RefSeq; YP_001633859.1; NC_010175.1.
DR ProteinModelPortal; A9WC77; -.
DR SMR; A9WC77; 3-346.
DR STRING; 324602.Caur_0217; -.
DR EnsemblBacteria; ABY33470; ABY33470; Caur_0217.
DR GeneID; 5824798; -.
DR KEGG; cau:Caur_0217; -.
DR PATRIC; 21410930; VBIChlAur28763_0251.
DR eggNOG; COG0136; -.
DR HOGENOM; HOG000013358; -.
DR KO; K00133; -.
DR OMA; VIDGHTE; -.
DR ProtClustDB; CLSK983887; -.
DR BioCyc; CAUR324602:GIXU-219-MONOMER; -.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004073; F:aspartate-semialdehyde dehydrogenase activity; IEA:EC.
DR GO; GO:0003942; F:N-acetyl-gamma-glutamyl-phosphate reductase activity; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0006531; P:aspartate metabolic process; IEA:InterPro.
DR GO; GO:0009097; P:isoleucine biosynthetic process; IEA:InterPro.
DR GO; GO:0009089; P:lysine biosynthetic process via diaminopimelate; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR GO; GO:0009088; P:threonine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; -; 1.
DR InterPro; IPR005676; Asp_semi-ald_DH_pep-lack.
DR InterPro; IPR012080; Asp_semialdehyde_DH.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR000534; Semialdehyde_DH_NAD-bd.
DR InterPro; IPR012280; Semialdhyde_DH_dimer_dom.
DR Pfam; PF01118; Semialdhyde_dh; 1.
DR Pfam; PF02774; Semialdhyde_dhC; 1.
DR PIRSF; PIRSF000148; ASA_dh; 1.
DR SMART; SM00859; Semialdhyde_dh; 1.
DR TIGRFAMs; TIGR00978; asd_EA; 1.
PE 3: Inferred from homology;
KW Complete proteome; Oxidoreductase; Reference proteome.
FT ACT_SITE 148 148 Acyl-thioester intermediate (By
FT similarity).
FT ACT_SITE 241 241 Proton acceptor (By similarity).
SQ SEQUENCE 349 AA; 37563 MW; 106E1F30A5FA39D8 CRC64;
MATIPVAVLG ATGAVGQRFI QLLEGHPLFQ VVALTGSERS AGKKYHEVCR WVLDTPMPAA
VANLTVLDAD ADLPAQLVFS ALPSTVAGPI EQRLAAAGHI VCSNASNHRM EPDVPLIIPE
VNPDHLALIP VQRRRRGWSG AIVTNPNCTS TPATMVLRPL LDTFGVRRML LVSMQALSGA
GYPGVPSYDV VDNVIPYIGG EEPKLEIEPQ KMLGRLEGET IVPAGFTTSA HCNRVPVLEG
HLVCLSIELE RKADPAEIAT VLSNFRALPQ ELRLPTAPEQ PIIVRHEPDR PQPRRDRDAG
RGMATVVGRI RPCSLFDIKL IALSHNTIRG AAGASILNAE LMHAQGWLA
//
