GenomeNet

Database: UniProt/TrEMBL
Entry: B0CUG3_LACBS
LinkDB: B0CUG3_LACBS
Original site: B0CUG3_LACBS 
ID   B0CUG3_LACBS            Unreviewed;      1059 AA.
AC   B0CUG3;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   07-JUN-2017, entry version 59.
DE   RecName: Full=DNA ligase {ECO:0000256|RuleBase:RU000617};
DE            EC=6.5.1.1 {ECO:0000256|RuleBase:RU000617};
GN   ORFNames=LACBIDRAFT_305524 {ECO:0000313|EMBL:EDR14086.1};
OS   Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured
OS   deceiver) (Laccaria laccata var. bicolor).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina;
OC   Agaricomycetes; Agaricomycetidae; Agaricales; Tricholomataceae;
OC   Laccaria.
OX   NCBI_TaxID=486041 {ECO:0000313|Proteomes:UP000001194};
RN   [1] {ECO:0000313|EMBL:EDR14086.1, ECO:0000313|Proteomes:UP000001194}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 / ATCC MYA-4686 {ECO:0000313|Proteomes:UP000001194};
RX   PubMed=18322534; DOI=10.1038/nature06556;
RA   Martin F., Aerts A., Ahren D., Brun A., Danchin E.G.J., Duchaussoy F.,
RA   Gibon J., Kohler A., Lindquist E., Pereda V., Salamov A.,
RA   Shapiro H.J., Wuyts J., Blaudez D., Buee M., Brokstein P.,
RA   Canbaeck B., Cohen D., Courty P.E., Coutinho P.M., Delaruelle C.,
RA   Detter J.C., Deveau A., DiFazio S., Duplessis S.,
RA   Fraissinet-Tachet L., Lucic E., Frey-Klett P., Fourrey C.,
RA   Feussner I., Gay G., Grimwood J., Hoegger P.J., Jain P., Kilaru S.,
RA   Labbe J., Lin Y.C., Legue V., Le Tacon F., Marmeisse R., Melayah D.,
RA   Montanini B., Muratet M., Nehls U., Niculita-Hirzel H.,
RA   Oudot-Le Secq M.P., Peter M., Quesneville H., Rajashekar B., Reich M.,
RA   Rouhier N., Schmutz J., Yin T., Chalot M., Henrissat B., Kuees U.,
RA   Lucas S., Van de Peer Y., Podila G.K., Polle A., Pukkila P.J.,
RA   Richardson P.M., Rouze P., Sanders I.R., Stajich J.E., Tunlid A.,
RA   Tuskan G., Grigoriev I.V.;
RT   "The genome of Laccaria bicolor provides insights into mycorrhizal
RT   symbiosis.";
RL   Nature 452:88-92(2008).
CC   -!- CATALYTIC ACTIVITY: ATP + (deoxyribonucleotide)(n)-3'-hydroxyl +
CC       5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) +
CC       AMP + diphosphate. {ECO:0000256|RuleBase:RU000617}.
CC   -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC       {ECO:0000256|RuleBase:RU004196}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; DS547092; EDR14086.1; -; Genomic_DNA.
DR   RefSeq; XP_001874645.1; XM_001874610.1.
DR   ProteinModelPortal; B0CUG3; -.
DR   STRING; 486041.XP_001874645.1; -.
DR   EnsemblFungi; EDR14086; EDR14086; LACBIDRAFT_305524.
DR   GeneID; 6070492; -.
DR   KEGG; lbc:LACBIDRAFT_305524; -.
DR   eggNOG; KOG0966; Eukaryota.
DR   eggNOG; COG1793; LUCA.
DR   InParanoid; B0CUG3; -.
DR   KO; K10777; -.
DR   OrthoDB; EOG092C18KW; -.
DR   Proteomes; UP000001194; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0071897; P:DNA biosynthetic process; IEA:InterPro.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd00027; BRCT; 1.
DR   Gene3D; 1.10.3260.10; -; 1.
DR   Gene3D; 3.40.50.10190; -; 2.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR000977; DNA_ligase_ATP-dep.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR   InterPro; IPR029710; LIG4.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   PANTHER; PTHR10459:SF84; PTHR10459:SF84; 1.
DR   Pfam; PF16589; BRCT_2; 2.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF04675; DNA_ligase_A_N; 1.
DR   SMART; SM00292; BRCT; 2.
DR   SUPFAM; SSF117018; SSF117018; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF52113; SSF52113; 2.
DR   TIGRFAMs; TIGR00574; dnl1; 1.
DR   PROSITE; PS50172; BRCT; 2.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000617};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001194};
KW   DNA damage {ECO:0000256|RuleBase:RU000617};
KW   DNA recombination {ECO:0000256|RuleBase:RU000617};
KW   DNA repair {ECO:0000256|RuleBase:RU000617};
KW   DNA replication {ECO:0000256|RuleBase:RU000617};
KW   Ligase {ECO:0000256|RuleBase:RU000617, ECO:0000313|EMBL:EDR14086.1};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000617};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001194}.
FT   DOMAIN      374    508       DNA_LIGASE_A3. {ECO:0000259|PROSITE:
FT                                PS50160}.
FT   DOMAIN      685    781       BRCT. {ECO:0000259|PROSITE:PS50172}.
FT   DOMAIN      981   1049       BRCT. {ECO:0000259|PROSITE:PS50172}.
SQ   SEQUENCE   1059 AA;  121081 MW;  949C5D6069D26E3E CRC64;
     MMQPTPAPSS APNSPERKLE PLAESQTYPA PPQNVGSAPF GVLVGLFDKL QVERKQDRRR
     KLIETWFNHW REEKGYDLYP VLRLILPQKD RERAVYGLKE KNLAKTYIKL IPLGMRDPDA
     IRLLNWKKPT EREKTSGDFP TVLYEVVSKR SSVIEGSLSI DELNDILDEL AKNMGKQDIQ
     SGILRRIYNR STAQEQRWIV RIILKDMIIS VKETTIFSVF HPDAQDLYNT CSDLKKIAWE
     LWDPSFRLNA EDKAVQLFHA FAPMLCKRPT KKIEETVREM SGSEFFIEEK LDGERMQLHK
     RGNEYLYFSR KGKDYTYLYG KHVGTGSLTP FIDKAFDPRV DDIILDGEML VWDPVSERNL
     PFGTLKTAAL DKSKKEHNPR PCFKVFDLLY LNGQSLLHKS TAFRKKNMRN CLKEITGRIE
     YAVDYKGTTA KDIRKRMDEV MGNRGEGLVI KHPLSKYVLN GRNMDWIKVK PEYMDNMGET
     VDVLVVAGNY GTGKRGGGVS TLICAVLDDR RANEDDEEPK YSTFVRIGSG LSFADYVWVR
     DKPWKVWDPK HPPEFLQTAK RTHEDKGDLY LEPEDSFILK VKAAEITPSD QYHMGFTMRF
     PRALSIRDDL SIADCMTATA VFESLRSEKK RKMESDAGVS SKKRKTTAKK ATVLPAYKGP
     NLKGVRVKTD ILDGLKFGEL LASCSIYQVL IRLTPVVMAD PKSRTGDEER KELMKLIHAN
     GGSCAQVANN QPELFIVYEG NTIPYDLKLL IDKNVYDVIK PNWITDSVAL GEPAPLRKKY
     FFRATDERAS TDEYMQEDED QAFEAPTLKE DPSAKLEEEM VPKVEEQEYD IDPSLADWLK
     IDDKNEKLHA EAKEEQDDYS ATDDDSDNAD VLEPEEVDLD DWLKVESADE PSVIASAATG
     SESLSTDCVD VKMGETEAAM EYDQDLIFKH LCFYLDSPEN AQRNQMIVKT RYEKDIKQRH
     VVVLRVCIEP VTDCAPPSFV DLSKVIADNG GKIVDLDEPK LTHIIIDKRD DSRRLELMKR
     TSKRRLIISE YVQACLDEGT LLDEDGAYHF RDDRRGCLT
//
DBGET integrated database retrieval system