ID   B0EIT0_ENTDS            Unreviewed;      1910 AA.
AC   B0EIT0;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   06-FEB-2013, entry version 40.
DE   SubName: Full=Protein serine/threonine kinase, putative;
DE            EC=2.7.11.25;
DE            EC=3.4.21.6;
DE            EC=3.4.21.75;
GN   ORFNames=EDI_156930;
OS   Entamoeba dispar (strain ATCC PRA-260 / SAW760).
OC   Eukaryota; Amoebozoa; Archamoebae; Entamoebidae; Entamoeba.
OX   NCBI_TaxID=370354;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC PRA-260 / SAW760;
RA   Lorenzi H., Inman J., Schobel S., Amedeo P., Caler E.;
RT   "Annotation of Entamoeba dispar SAW760.";
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS549491; EDR25578.1; -; Genomic_DNA.
DR   RefSeq; XP_001738120.1; XM_001738068.1.
DR   ProteinModelPortal; B0EIT0; -.
DR   GeneID; 5883188; -.
DR   KEGG; edi:EDI_156930; -.
DR   EuPathDB; AmoebaDB:EDI_156930; -.
DR   ProtClustDB; CLSZ2735096; -.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.
DR   GO; GO:0000186; P:activation of MAPKK activity; IEA:GOC.
DR   GO; GO:0000165; P:MAPK cascade; IEA:GOC.
DR   InterPro; IPR000742; EG-like_dom.
DR   InterPro; IPR006212; Furin_repeat.
DR   InterPro; IPR009030; Growth_fac_rcpt.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR000719; Prot_kinase_cat_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   Pfam; PF07714; Pkinase_Tyr; 1.
DR   SMART; SM00181; EGF; 3.
DR   SMART; SM00261; FU; 15.
DR   SUPFAM; SSF57184; Grow_fac_recept; 9.
DR   SUPFAM; SSF56112; Kinase_like; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   Complete proteome; Hydrolase; Kinase; Repeat; Transferase.
SQ   SEQUENCE   1910 AA;  212630 MW;  88482D3DF6BFDA58 CRC64;
     MFLELVSILI VTSWSCAIGE YFFYFSCYGC PNGYFCPGDD YDYSCNCNSC NNINGICYSS
     CSTGYVKDEI GRCQKCAPGY YRSSERICSK CDNGYYCPGD GFQYKANCYR FNKQTGVCNS
     NCYLGYVKSA DGKCQECSSS YFMNEGSCLS CNCDSCNSTT GVCFSKCDSQ TSYSNGFCSY
     CNPGNYYKKI YSYSCYSCKK SLYCPGNDNA YYCNCRNCDS TTGNCKSYCY AGYEKESSTG
     RCIPCQEGYY SIGDGEQCKK CGCSICDKKQ GCSIGCDPGY SYDSNKRQCT ICSSGSYSIG
     GKGSCLSCEG NTISSVEGSS LCEPCPTNQV ANLQKTVCEY CVEGKYFSNG VCLPCPDGKI
     KEDRTTSYCH SCERNEISNS DHTQCLQCEA GKYKNGNSCS YCGPNQYSLK GAISCLSCDS
     SCLSCDPTNG YCLTCNKGSY LNTQTNKCEL CPAGTYSSIT TANSCNKCLE QEWSPSGSIT
     CFPCNENCQE CDNTNGRCRS CPKGYGYDAK NGICTICKIG TYSSGGINGC YVCNVGSVQP
     QMGQSSCEPC GDGFYQDAKE SSTCKPCSSS CSSCSKTTGA CLSCKEGYGL SNGVCSECPP
     GTHNPVTNTG MCISCESGTY SNLPQQQNCI ECPQLYWSNP NSISCKVCDE SCKSCDKTNG
     KCLTCKPGYG INLKDGTCTA CGYGNYSNGE TSVCQICEDG YYTNQIKQEV CQPCSSSCSE
     CDKLSGECIH CKAGHQLENG ICKTCQEMTY SLLNQDKCTS CDSSCKQCSS VTGKCTSCPN
     GEKTVSGVCR SCAINGHCVL CSLETNEEER QCKQCSDGYY FKSNNCYECN KLDPNCLACN
     PSEEKCISCS GNTILNELGT KCVPCKDGEV KISETQCVPC SSKIEGCSSC IFNSISNIKC
     ASCYAPYELT NEQTSCINCL TQLNSYYDQD TKRCITNNQG CLDQVRKTEC INCDSNNYYL
     RNGICSTFDS QCTKKTSKGC EECSNLIIPN NSQCNINIEH CKYGMSSTQD ICYLCELNYQ
     NNNGNCEQTT GKCQYYQNEY CLLCNEGISN GKQCVSCNKG VSVCIYYHNK EVPIRCSDGY
     FLGSNNECVE KTTTNCQIIN NSYCIQCGPH QYINHGNCKN NNEECEIEDK NGCLKCNDGI
     SINGECQSTT TLNCNKVNKN QCLECKDNNY RNINTCSPID TLSTELKQCK TYNVITEKCL
     ECSNEYLLYH NTKCQAKQEP QQNKIKKEGT IDNCFERTSK GCLRCKSGYY LEDGDCLECQ
     GDCWECSSKD YCTGCDPYSY PSNGKCIKMN DLVQRCDQMM STYTGCVNCK EGYYKAEDGK
     NCNKCDKSCL SCMKNNTCIQ CAEDYFRYGL ELSTLCLPQT QINNCLNKTK HGCEICEDGY
     YRTSVYQCKK CRVNCTSCSN ENQCLSCITE NVLGTNGNCL HYSFISNCIN SSESKCSECS
     KGYRLDDEET GCVEKKKNIG MIIGITIGTF IIVLIIVITI IIIISLFYIQ HKKEKKKMDN
     ICVFEMKRSN IKMEELYDVI CSNTNEINFN SDRDKIKVNE ESRELVCIGN NGNNRIKVQF
     TTQDGNEKYN IRTEPKIITL KKGEACEFEI FIIPLCTCTI EDDITIVGLD IGTSKEIIAP
     MKIKFDTELT TRLDPDELIE EKKIGEGSFG IVYIGKFRGS KVAIKKMKEI AQTKTAIDEF
     EKEVAMLDKF RSEYIIHFYG AVMIPGKVCM VTEYAKYGSL QDMIDKRKET LIPMKMKIKF
     MIDAAKGIQY LHSNGILHRD IKPDNILVIS IEENEQINCK LTDFGSARNV NLMMTNMTFT
     KGIGSPKYMA PEILNKEHYK MPSDIYSLAV SMYQTWSWKN PYDKDESSQF KYPWKIAEFV
     TSGKRLERVP TIPEKLYNVI EECWKQIPEE RIKINNLVEI LEQQYQNETN
//