ID B0SY79_CAUSK Unreviewed; 208 AA.
AC B0SY79;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 01-MAY-2013, entry version 34.
DE RecName: Full=Thymidylate kinase;
DE EC=2.7.4.9;
DE AltName: Full=dTMP kinase;
GN Name=tmk; OrderedLocusNames=Caul_2699;
OS Caulobacter sp. (strain K31).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=366602;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K31;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Thompson L.S.,
RA Brettin T., Detter J.C., Han C., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Kim E., Stephens C., Richardson P.;
RT "Complete sequence of chromosome of Caulobacter sp. K31.";
RL Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Phosphorylation of dTMP to form dTDP in both de novo and
CC salvage pathways of dTTP synthesis (By similarity).
CC -!- CATALYTIC ACTIVITY: ATP + dTMP = ADP + dTDP.
CC -!- SIMILARITY: Belongs to the thymidylate kinase family.
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DR EMBL; CP000927; ABZ71826.1; -; Genomic_DNA.
DR RefSeq; YP_001684324.1; NC_010338.1.
DR ProteinModelPortal; B0SY79; -.
DR STRING; 366602.Caul_2699; -.
DR EnsemblBacteria; ABZ71826; ABZ71826; Caul_2699.
DR GeneID; 5900154; -.
DR KEGG; cak:Caul_2699; -.
DR PATRIC; 21318470; VBICauSp18104_3093.
DR eggNOG; COG0125; -.
DR HOGENOM; HOG000229078; -.
DR KO; K00943; -.
DR OMA; ITLEGPE; -.
DR ProtClustDB; PRK13973; -.
DR BioCyc; CSP366602:GH0Y-2697-MONOMER; -.
DR GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR GO; GO:0004798; F:thymidylate kinase activity; IEA:HAMAP.
DR GO; GO:0006233; P:dTDP biosynthetic process; IEA:InterPro.
DR GO; GO:0006235; P:dTTP biosynthetic process; IEA:HAMAP.
DR HAMAP; MF_00165; Thymidylate_kinase; 1; -.
DR InterPro; IPR018095; Thymidylate_kin_CS.
DR InterPro; IPR018094; Thymidylate_kinase.
DR PANTHER; PTHR10344; PTHR10344; 1.
DR TIGRFAMs; TIGR00041; DTMP_kinase; 1.
DR PROSITE; PS01331; THYMIDYLATE_KINASE; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; Kinase; Nucleotide biosynthesis;
KW Nucleotide-binding; Transferase.
FT NP_BIND 11 18 ATP (By similarity).
SQ SEQUENCE 208 AA; 22511 MW; 8FB91E0197DA7911 CRC64;
MTRGTFISFE GGEGAGKSTQ IRRLAERLKA DGADVVLTRE PGGSPGAEQI RDLILNGHVD
RWSPITETLL MYASRRDHVE RVIRPALERG AIVLCDRFAD STRAYQGAGG EAPIALIKAL
EEHVLGGTVP DLTLIFDIPA EVGLARALAR GGEARFESKG LAFHERLGEA FLEIARREPE
RCVVIEADDA IDAVWADVWG AVSARLGL
//
