GenomeNet

Database: UniProt/TrEMBL
Entry: B1ICD8_STRPI
LinkDB: B1ICD8_STRPI
Original site: B1ICD8_STRPI 
ID   B1ICD8_STRPI            Unreviewed;       740 AA.
AC   B1ICD8;
DT   29-APR-2008, integrated into UniProtKB/TrEMBL.
DT   29-APR-2008, sequence version 1.
DT   25-OCT-2017, entry version 63.
DE   SubName: Full=Sialidase B (Neuraminidase B) {ECO:0000313|EMBL:ACA36743.1};
DE            EC=3.2.1.18 {ECO:0000313|EMBL:ACA36743.1};
GN   OrderedLocusNames=SPH_1468 {ECO:0000313|EMBL:ACA36743.1};
OS   Streptococcus pneumoniae (strain Hungary19A-6).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=487214 {ECO:0000313|EMBL:ACA36743.1, ECO:0000313|Proteomes:UP000002163};
RN   [1] {ECO:0000313|Proteomes:UP000002163}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hungary19A-6 {ECO:0000313|Proteomes:UP000002163};
RX   PubMed=21034474; DOI=10.1186/gb-2010-11-10-r107;
RA   Donati C., Hiller N.L., Tettelin H., Muzzi A., Croucher N.J.,
RA   Angiuoli S.V., Oggioni M., Dunning Hotopp J.C., Hu F.Z., Riley D.R.,
RA   Covacci A., Mitchell T.J., Bentley S.D., Kilian M., Ehrlich G.D.,
RA   Rappuoli R., Moxon E.R., Masignani V.;
RT   "Structure and dynamics of the pan-genome of Streptococcus pneumoniae
RT   and closely related species.";
RL   Genome Biol. 11:R107.1-R107.19(2010).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000936; ACA36743.1; -; Genomic_DNA.
DR   RefSeq; WP_000739360.1; NC_010380.1.
DR   ProteinModelPortal; B1ICD8; -.
DR   SMR; B1ICD8; -.
DR   CAZy; CBM40; Carbohydrate-Binding Module Family 40.
DR   CAZy; GH33; Glycoside Hydrolase Family 33.
DR   EnsemblBacteria; ACA36743; ACA36743; SPH_1468.
DR   KEGG; spv:SPH_1468; -.
DR   HOGENOM; HOG000285031; -.
DR   KO; K01186; -.
DR   OMA; DAPNHIN; -.
DR   BioCyc; SPNE487214:GHY0-1354-MONOMER; -.
DR   Proteomes; UP000002163; Chromosome.
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   InterPro; IPR002860; BNR_rpt.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR004124; Glyco_hydro_33_N.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; PTHR10628; 1.
DR   Pfam; PF02012; BNR; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   Pfam; PF02973; Sialidase; 1.
DR   SUPFAM; SSF49899; SSF49899; 1.
DR   SUPFAM; SSF50939; SSF50939; 2.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002163};
KW   Glycosidase {ECO:0000313|EMBL:ACA36743.1};
KW   Hydrolase {ECO:0000313|EMBL:ACA36743.1};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     27       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        28    740       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002765685.
FT   DOMAIN       98    269       Sialidase. {ECO:0000259|Pfam:PF02973}.
FT   DOMAIN      501    703       Sialidase. {ECO:0000259|Pfam:PF13088}.
SQ   SEQUENCE   740 AA;  82437 MW;  51101837A55FA4A7 CRC64;
     MKKNIKQYVT LGTVVVLSAF VANSVAAQET ETSEVSTPKL VQPVAPTTPI SEVQPTSDNS
     SEVTVQPRTV ETTVKDPSST AEETPVLEKN NVTLTGGGEN VTKELKDKFT SGDFTVVIKY
     NQSSEKGLQA LFGISNSKPG QQNSYVDVFL RDNGELGMEA RDTSSNKNNL VSRPASVWGK
     YKQEAVTNTV AVVADSVKKT YSLYANGTKV VEKKVDNFLN IKDIKGIDYY MLGGVKRAGK
     TAFGFNGTLE NIKFFNSALD EETVKKMTTN AVTGHLIYTA NDTTGSNYFR IPVLYTFSNG
     RVFSSIDARY GGTHDFLNKI NIATSYSDDN GKTWTKPKLT LAFDDFAPVP LEWPREVGGR
     DLQISGGATY IDSVIVEKKN KQVLMFADVM PAGVSFREAT RKDSGYKQID GNYYLKLRKQ
     GDTDYNYTIR ENGTVYDDRT NRPTEFSVDK NFGIKQNGNY LTVEQYSVSF ENNKKTEYRN
     GTKVHMNIFY KDALFKVVPT NYIAYISSND HGESWSAPTL LPPIMGLNRN APYLGPGRGI
     IESSTGRILI PSYTGKESAF IYSDDNGASW KVKVVPLPSS WSAEAQFVEL SPGVIQAYMR
     TNNGKIAYLT SKDAGTTWSA PEYLKFVSNP SYGTQLSIIN YSQLIDGKKA VILSTPNSTN
     GRKHGQIWIG LINDDNTIDW RYHHDVDYSN YGYSYSTLTE LPNHEIGLMF EKFDSWSRNE
     LHMKNVVPYI TFKIEDLKKN
//
DBGET integrated database retrieval system