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Database: UniProt/TrEMBL
Entry: B1PE19_CUCSA
LinkDB: B1PE19_CUCSA
Original site: B1PE19_CUCSA 
ID   B1PE19_CUCSA            Unreviewed;       152 AA.
AC   B1PE19;
DT   29-APR-2008, integrated into UniProtKB/TrEMBL.
DT   29-APR-2008, sequence version 1.
DT   28-FEB-2018, entry version 62.
DE   RecName: Full=Superoxide dismutase [Cu-Zn] {ECO:0000256|RuleBase:RU000393};
DE            EC=1.15.1.1 {ECO:0000256|RuleBase:RU000393};
GN   Name=SOD {ECO:0000313|EMBL:ACA49507.1};
GN   ORFNames=Csa_1G573600 {ECO:0000313|EMBL:KGN66141.1};
OS   Cucumis sativus (Cucumber).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae;
OC   Benincaseae; Cucumis.
OX   NCBI_TaxID=3659 {ECO:0000313|EMBL:ACA49507.1};
RN   [1] {ECO:0000313|EMBL:ACA49507.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Cotyledon {ECO:0000313|EMBL:ACA49507.1};
RA   Kim D.-J.;
RT   "A study of cotyledon senescence in cucumber; cucumber cytosolic
RT   superoxide dismutase cDNA.";
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KGN66141.1, ECO:0000313|Proteomes:UP000029981}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=19881527; DOI=10.1038/ng.475;
RA   Huang S., Li R., Zhang Z., Li L., Gu X., Fan W., Lucas W.J., Wang X.,
RA   Xie B., Ni P., Ren Y., Zhu H., Li J., Lin K., Jin W., Fei Z., Li G.,
RA   Staub J., Kilian A., van der Vossen E.A., Wu Y., Guo J., He J.,
RA   Jia Z., Ren Y., Tian G., Lu Y., Ruan J., Qian W., Wang M., Huang Q.,
RA   Li B., Xuan Z., Cao J., Asan null, Wu Z., Zhang J., Cai Q., Bai Y.,
RA   Zhao B., Han Y., Li Y., Li X., Wang S., Shi Q., Liu S., Cho W.K.,
RA   Kim J.Y., Xu Y., Heller-Uszynska K., Miao H., Cheng Z., Zhang S.,
RA   Wu J., Yang Y., Kang H., Li M., Liang H., Ren X., Shi Z., Wen M.,
RA   Jian M., Yang H., Zhang G., Yang Z., Chen R., Liu S., Li J., Ma L.,
RA   Liu H., Zhou Y., Zhao J., Fang X., Li G., Fang L., Li Y., Liu D.,
RA   Zheng H., Zhang Y., Qin N., Li Z., Yang G., Yang S., Bolund L.,
RA   Kristiansen K., Zheng H., Li S., Zhang X., Yang H., Wang J., Sun R.,
RA   Zhang B., Jiang S., Wang J., Du Y., Li S.;
RT   "The genome of the cucumber, Cucumis sativus L.";
RL   Nat. Genet. 41:1275-1281(2009).
RN   [3] {ECO:0000313|EMBL:KGN66141.1, ECO:0000313|Proteomes:UP000029981}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=19495411; DOI=10.1371/journal.pone.0005795;
RA   Ren Y., Zhang Z., Liu J., Staub J.E., Han Y., Cheng Z., Li X., Lu J.,
RA   Miao H., Kang H., Xie B., Gu X., Wang X., Du Y., Jin W., Huang S.;
RT   "An integrated genetic and cytogenetic map of the cucumber genome.";
RL   PLoS ONE 4:E5795-E5795(2009).
RN   [4] {ECO:0000313|EMBL:KGN66141.1, ECO:0000313|Proteomes:UP000029981}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20565788; DOI=10.1186/1471-2164-11-384;
RA   Guo S., Zheng Y., Joung J.G., Liu S., Zhang Z., Crasta O.R.,
RA   Sobral B.W., Xu Y., Huang S., Fei Z.;
RT   "Transcriptome sequencing and comparative analysis of cucumber flowers
RT   with different sex types.";
RL   BMC Genomics 11:384-384(2010).
RN   [5] {ECO:0000313|EMBL:KGN66141.1, ECO:0000313|Proteomes:UP000029981}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22047402; DOI=10.1186/1471-2164-12-540;
RA   Li Z., Zhang Z., Yan P., Huang S., Fei Z., Lin K.;
RT   "RNA-Seq improves annotation of protein-coding genes in the cucumber
RT   genome.";
RL   BMC Genomics 12:540-540(2011).
RN   [6] {ECO:0000313|EMBL:KGN66141.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Huang S., Zhang Z., Lin K., Zhou Q.;
RL   Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Destroys radicals which are normally produced within the
CC       cells and which are toxic to biological systems.
CC       {ECO:0000256|RuleBase:RU000393}.
CC   -!- CATALYTIC ACTIVITY: 2 superoxide + 2 H(+) = O(2) + H(2)O(2).
CC       {ECO:0000256|RuleBase:RU000393}.
CC   -!- COFACTOR:
CC       Name=Cu cation; Xref=ChEBI:CHEBI:23378;
CC         Evidence={ECO:0000256|RuleBase:RU000393};
CC       Note=Binds 1 copper ion per subunit.
CC       {ECO:0000256|RuleBase:RU000393};
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU000393};
CC       Note=Binds 1 zinc ion per subunit.
CC       {ECO:0000256|RuleBase:RU000393};
CC   -!- SIMILARITY: Belongs to the Cu-Zn superoxide dismutase family.
CC       {ECO:0000256|RuleBase:RU000393}.
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DR   EMBL; EU407180; ACA49507.1; -; mRNA.
DR   EMBL; CM002922; KGN66141.1; -; Genomic_DNA.
DR   RefSeq; NP_001267697.1; NM_001280768.1.
DR   RefSeq; XP_011658153.1; XM_011659851.1.
DR   RefSeq; XP_011658519.1; XM_011660217.1.
DR   ProteinModelPortal; B1PE19; -.
DR   SMR; B1PE19; -.
DR   EnsemblPlants; KGN66141; KGN66141; Csa_1G573600.
DR   GeneID; 101215417; -.
DR   Gramene; KGN66141; KGN66141; Csa_1G573600.
DR   KEGG; csv:101215417; -.
DR   KO; K04565; -.
DR   Proteomes; UP000029981; Chromosome 1.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
DR   CDD; cd00305; Cu-Zn_Superoxide_Dismutase; 1.
DR   Gene3D; 2.60.40.200; -; 1.
DR   InterPro; IPR036423; SOD-like_Cu/Zn_dom_sf.
DR   InterPro; IPR024134; SOD_Cu/Zn_/chaperone.
DR   InterPro; IPR018152; SOD_Cu/Zn_BS.
DR   InterPro; IPR001424; SOD_Cu_Zn_dom.
DR   PANTHER; PTHR10003; PTHR10003; 1.
DR   Pfam; PF00080; Sod_Cu; 1.
DR   PRINTS; PR00068; CUZNDISMTASE.
DR   SUPFAM; SSF49329; SSF49329; 1.
DR   PROSITE; PS00087; SOD_CU_ZN_1; 1.
DR   PROSITE; PS00332; SOD_CU_ZN_2; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000029981};
KW   Copper {ECO:0000256|RuleBase:RU000393};
KW   Metal-binding {ECO:0000256|RuleBase:RU000393};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000393,
KW   ECO:0000313|EMBL:ACA49507.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029981};
KW   Zinc {ECO:0000256|RuleBase:RU000393}.
FT   DOMAIN       12    148       Sod_Cu. {ECO:0000259|Pfam:PF00080}.
SQ   SEQUENCE   152 AA;  15262 MW;  C001D0D0AC060819 CRC64;
     MVKAVAVLGS SEGVSGTIFF TQEGDGPTTV TGNVSGLKPG LHGFHVHALG DTTNGCMSTG
     PHFNPAGKQH GAPEDENRHA GDLGNIIVGE DGKANFTITD CQIPLCGHES IIGRAVVVHG
     DPDDLGKGGH ELSSSTGNAG ARVACGIIGL QG
//
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