ID   B2TTP2_SHIB3            Unreviewed;      1320 AA.
AC   B2TTP2;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   29-MAY-2013, entry version 38.
DE   SubName: Full=Bifunctional protein PutA;
DE            EC=1.5.1.12;
DE            EC=1.5.99.8;
GN   Name=putA; OrderedLocusNames=SbBS512_E2304;
OS   Shigella boydii serotype 18 (strain CDC 3083-94 / BS512).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=344609;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 3083-94 / BS512;
RA   Rasko D.A., Rosovitz M., Maurelli A.T., Myers G., Seshadri R., Cer R.,
RA   Jiang L., Ravel J., Sebastian Y.;
RT   "Complete sequence of Shigella boydii serotype 18 strain BS512.";
RL   Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
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DR   EMBL; CP001063; ACD08633.1; -; Genomic_DNA.
DR   RefSeq; YP_001880799.1; NC_010658.1.
DR   ProteinModelPortal; B2TTP2; -.
DR   STRING; 344609.SbBS512_E2304; -.
DR   EnsemblBacteria; ACD08633; ACD08633; SbBS512_E2304.
DR   GeneID; 6269647; -.
DR   KEGG; sbc:SbBS512_E2304; -.
DR   PATRIC; 18671565; VBIShiBoy129590_2546.
DR   eggNOG; COG0506; -.
DR   HOGENOM; HOG000253911; -.
DR   KO; K13821; -.
DR   OMA; TGGINAM; -.
DR   ProtClustDB; PRK11809; -.
DR   BioCyc; SBOY344609:GI0O-2306-MONOMER; -.
DR   GO; GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0004657; F:proline dehydrogenase activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006537; P:glutamate biosynthetic process; IEA:InterPro.
DR   GO; GO:0006561; P:proline biosynthetic process; IEA:InterPro.
DR   GO; GO:0010133; P:proline catabolic process to glutamate; IEA:InterPro.
DR   Gene3D; 1.10.2060.10; -; 1.
DR   Gene3D; 1.20.5.550; -; 1.
DR   Gene3D; 3.40.309.10; -; 1.
DR   Gene3D; 3.40.605.10; -; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR025703; Bifunct_PutA.
DR   InterPro; IPR005933; Delta1-pyrroline-5-COlate_DH-3.
DR   InterPro; IPR024090; PRODH_PutA_dom_I.
DR   InterPro; IPR024089; PRODH_PutA_dom_I/II.
DR   InterPro; IPR024082; PRODH_PutA_dom_II.
DR   InterPro; IPR002872; Proline_DH.
DR   Pfam; PF00171; Aldedh; 1.
DR   Pfam; PF01619; Pro_dh; 1.
DR   PIRSF; PIRSF000197; Bifunct_PutA; 1.
DR   SUPFAM; SSF53720; Aldehyde_DH/Histidinol_DH; 1.
DR   SUPFAM; SSF81935; SSF81935; 1.
DR   TIGRFAMs; TIGR01238; D1pyr5carbox3; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Oxidoreductase.
SQ   SEQUENCE   1320 AA;  143694 MW;  448BBC9E6922BEB8 CRC64;
     MGTTTMGVKL DDATRERIKS AATRIDRTPH WLIKQAIFSY LEQLENSDTL PELPALLSGA
     ANESDEAPTP AEEPHQPFLD FAEQILPQSV SRAAITAAYR RPETEAVSML LEQARLPQPV
     AEQAHKLAYQ LADKLRNQKN ASGRAGMVQG LLQEFSLSSQ EGVALMCLAE ALLRIPDKAT
     RDALIRDKIS NGNWQSHIGR SPSLFVNAAT WGLLFTGKLV STHNEASLSR SLNRIIGKSG
     EPLIRKGVDM AMRLMGEQFV TGETIAEALV NARKLEEKGF RYSYDMLGEA ALTAADAQAY
     MVSYQQAIHA IGKASNGRGI YEGPGISIKL SALHPRYSRA QYDRVMEELY PRLKSLTLLA
     RQYDIGINID AEEADRLEIS LDLLENLCFE PELAGWNGIG FVIQAYQKRC PLVIDYLVDL
     ATRSRRRLMI RLVKGAYWDS EIKRAQMDGL EGYPVYTRKV YTDVSYLACA KKLLAVPNLI
     YPQFATHNAH TLAAIYQLAG QNYYPGQYEF QCLHGMGEPL YEQVTGKVAD GKLNRPCRIY
     APVGTHETLL AYLVRRLLEN GANTSFVNRI ADTSLPLDEL VADPVTAVEK LAQQEGQTGL
     PHPKIPLPRD LYGHGRDNSA GLDLANEHRL ASLSSALLNS ALQKWQALPM LEQPVAAGEM
     SPVINPAEPK DIVGFVREAT PREVEQALES AVNNAPIWFA TPPAERAAIL HRAAVLMESQ
     MQQLIGILVR EAGKTFSNAI AEVREAVDFL HYYAGQVRDD FANETHRPLG PVVCISPWNF
     PLAIFTGQIA AALAAGNSVL AKPAEQTPLI AAQGIAILLE AGVPPGVVQL LPGQGETVGA
     QLTGDDRVRG VMFTGSTEVA TLLQCNIASR LDAQGRPIPL IAETGGMNAM IVDSSALTEQ
     VVVDVLASAF DSAGQRCSAL RVLCLQDEIA DHTLKMLRGA MAECRMGNPG RLTTDIGPVI
     DSEAKANIER HIQTMRSKGR PVFQAVRENS EDAREWQSGT FVAPTLIELD DFAELHKEVF
     GPVLHVVRYN RNQLPELIEQ INASGYGLTL GVHTRIDETI AQVTGSAHVG NLYVNRNMVG
     AVVGVQPFGG EGLSGTGPKA GGPLYLYRLL ANRPESALAV TLARQDAEYP VDAQLKAALT
     QPLNALREWA ANRPELQALC TQYGELAQAG IQRLLPGPTG ERNTWTLLPR ERVLCIADDE
     QDALTQLAAV LAVGSQVLWP DDALHRQLVK ALPSAVSERI QLAKAENITA QPFDAVIFHG
     DSDQLRALCE AVAARDGAIV SVQGFARGES NILLERLYIE RSLSVNTAAA GGNASLMTIG
//