ID   B3DNW7_BIFLD            Unreviewed;       488 AA.
AC   B3DNW7;
DT   22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2008, sequence version 1.
DT   27-MAR-2024, entry version 61.
DE   SubName: Full=Cell division protein {ECO:0000313|EMBL:ACD98826.1};
GN   Name=ftsI2 {ECO:0000313|EMBL:ACD98826.1};
GN   OrderedLocusNames=BLD_1381 {ECO:0000313|EMBL:ACD98826.1};
OS   Bifidobacterium longum (strain DJO10A).
OC   Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC   Bifidobacteriaceae; Bifidobacterium.
OX   NCBI_TaxID=205913 {ECO:0000313|EMBL:ACD98826.1, ECO:0000313|Proteomes:UP000002419};
RN   [1] {ECO:0000313|EMBL:ACD98826.1, ECO:0000313|Proteomes:UP000002419}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DJO10A {ECO:0000313|EMBL:ACD98826.1,
RC   ECO:0000313|Proteomes:UP000002419};
RX   PubMed=16391088; DOI=10.1128/AEM.72.1.527-535.2006;
RA   Lee J.H., O'Sullivan D.J.;
RT   "Sequence analysis of two cryptic plasmids from Bifidobacterium longum
RT   DJO10A and construction of a shuttle cloning vector.";
RL   Appl. Environ. Microbiol. 72:527-535(2006).
RN   [2] {ECO:0000313|EMBL:ACD98826.1, ECO:0000313|Proteomes:UP000002419}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DJO10A {ECO:0000313|EMBL:ACD98826.1,
RC   ECO:0000313|Proteomes:UP000002419};
RX   PubMed=18505588; DOI=10.1186/1471-2164-9-247;
RA   Lee J.H., Karamychev V.N., Kozyavkin S.A., Mills D., Pavlov A.R.,
RA   Pavlova N.V., Polouchine N.N., Richardson P.M., Shakhova V.V.,
RA   Slesarev A.I., Weimer B., O'Sullivan D.J.;
RT   "Comparative genomic analysis of the gut bacterium Bifidobacterium longum
RT   reveals loci susceptible to deletion during pure culture growth.";
RL   BMC Genomics 9:247-247(2008).
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
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DR   EMBL; CP000605; ACD98826.1; -; Genomic_DNA.
DR   RefSeq; WP_010081520.1; NZ_AABM02000020.1.
DR   AlphaFoldDB; B3DNW7; -.
DR   KEGG; blj:BLD_1381; -.
DR   HOGENOM; CLU_009289_1_0_11; -.
DR   Proteomes; UP000002419; Chromosome.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000313|EMBL:ACD98826.1};
KW   Cell division {ECO:0000313|EMBL:ACD98826.1}.
FT   DOMAIN          157..483
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   488 AA;  51207 MW;  493AEAB350F51761 CRC64;
     MNKYLRQLFT AVVALFVILG LSSTIIMAVR ANALNNDPRN ARSLYHQLGA YRGAILASDG
     TVMAKSEPVN DAFKYLRTYS NGPLYAPVTG FFSINQTADR GLEASRSMLL NGEADSLIWQ
     RAKAMLTGTT NQGASIETSI DPKLQQVAYD QLGTRDGAAV AIEVNTGRIL AMVSTPSYDP
     NKLATHDTKA ASQAYNELSA GQNSPLINRA TSQLYPPGST FKTIVASAAL ETGDYQTDTK
     IPAGSSYTLP GTATQLPNDE AQADGVNGQI SLQEAVAWSS NTAFAQLGVK LGASKVSDMA
     TKLGFGSTIT IDGTESTGTP MTATASTFPS DPTDDKLALA SIGQGDTTAT PLQMAMVAQA
     IANNGKLMQP TLVDRVRAAD LTVLSQTKPQ TMANAFSEDS ADKLTTMMES VVTEANPQLA
     IDGIKVAAKT GTAQIGTDNS AIDGWVIGFA PADDPQIAVA VLVHNTDVYG SLAAGPIMRA
     MMQEALQQ
//