ID B3R616_CUPTR Unreviewed; 470 AA.
AC B3R616;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 01-MAY-2013, entry version 38.
DE RecName: Full=Argininosuccinate lyase;
DE Short=ASAL;
DE EC=4.3.2.1;
DE AltName: Full=Arginosuccinase;
GN Name=argH; OrderedLocusNames=RALTA_A2407;
OS Cupriavidus taiwanensis (strain R1 / LMG 19424) (Ralstonia taiwanensis
OS (strain LMG 19424)).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=164546;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R1 / LMG 19424;
RX PubMed=18490699; DOI=10.1101/gr.076448.108;
RA Amadou C., Pascal G., Mangenot S., Glew M., Bontemps C., Capela D.,
RA Carrere S., Cruveiller S., Dossat C., Lajus A., Marchetti M.,
RA Poinsot V., Rouy Z., Servin B., Saad M., Schenowitz C., Barbe V.,
RA Batut J., Medigue C., Masson-Boivin C.;
RT "Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and
RT comparative genomics of rhizobia.";
RL Genome Res. 18:1472-1483(2008).
CC -!- CATALYTIC ACTIVITY: 2-(N(omega)-L-arginino)succinate = fumarate +
CC L-arginine.
CC -!- PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; L-
CC arginine from L-ornithine and carbamoyl phosphate: step 3/3.
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the lyase 1 family. Argininosuccinate lyase
CC subfamily.
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DR EMBL; CU633749; CAQ70341.1; -; Genomic_DNA.
DR RefSeq; YP_002006402.1; NC_010528.1.
DR ProteinModelPortal; B3R616; -.
DR STRING; 164546.RALTA_A2407; -.
DR EnsemblBacteria; CAQ70341; CAQ70341; RALTA_A2407.
DR GeneID; 6453732; -.
DR KEGG; cti:RALTA_A2407; -.
DR PATRIC; 21531450; VBICupTai42494_2365.
DR eggNOG; COG0165; -.
DR HOGENOM; HOG000242744; -.
DR KO; K01755; -.
DR OMA; KEGIFDA; -.
DR ProtClustDB; PRK00855; -.
DR BioCyc; CTAI164546:GJNE-2401-MONOMER; -.
DR UniPathway; UPA00068; UER00114.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004056; F:argininosuccinate lyase activity; IEA:HAMAP.
DR GO; GO:0042450; P:arginine biosynthetic process via ornithine; IEA:InterPro.
DR Gene3D; 1.10.275.10; -; 1.
DR HAMAP; MF_00006; Arg_succ_lyase; 1; -.
DR InterPro; IPR009049; Argininosuccinate_lyase.
DR InterPro; IPR003031; D_crystallin.
DR InterPro; IPR024083; Fumarase/histidase_N.
DR InterPro; IPR000362; Fumarate_lyase.
DR InterPro; IPR020557; Fumarate_lyase_CS.
DR InterPro; IPR022761; Fumarate_lyase_N.
DR InterPro; IPR008948; L-Aspartase-like.
DR PANTHER; PTHR11444:SF3; PTHR11444:SF3; 1.
DR Pfam; PF00206; Lyase_1; 1.
DR PRINTS; PR00145; ARGSUCLYASE.
DR PRINTS; PR00149; FUMRATELYASE.
DR SUPFAM; SSF48557; L-Aspartase-like; 1.
DR TIGRFAMs; TIGR00838; argH; 1.
DR PROSITE; PS00163; FUMARATE_LYASES; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis; Arginine biosynthesis; Complete proteome;
KW Cytoplasm; Lyase.
SQ SEQUENCE 470 AA; 51113 MW; CB29BA81D230489E CRC64;
MSTSQLAKKG EAWSARFSEP MSDLVKRYTA SVFFDKRLAL FDIQGSLAHA AMLAKQGIIA
EADRAEIERG MAQIRGEIEA GSFEWKLDLE DVHLNIEARL TALVGDAGKR LHTGRSRNDQ
VATDIRLWLR SEIDNIIALL GALRTSLLDL AEQNADTILP GFTHLQVAQP VTFGHHLLAY
NEMFTRDAER MADCRKRVNR LPLGAAALAG TSYPIDREFV AQQLGFDGVC RNSLDAVSDR
DFAIEFCAAA ALVMTHVSRF SEELVLWMSP RVGFIDIADR FCTGSSIMPQ KKNPDVPELA
RGKTGRVNGH LIGLLTLMKG QPLAYNKDNQ EDKEPLFDTV DTVVDTLRIF ADMVPGISVK
PEAMRAAALQ GYATATDLAD YLVKKGLPFR DAHEAVAHAV RACDGRQCDL ADLTVAELRE
VSGLGDKAAL IGDDVHAVLT LEGSVAARNH VGGTAPDQVR AAIAAARAAL
//
