GenomeNet

Database: UniProt/TrEMBL
Entry: B4E8C5_BURCJ
LinkDB: B4E8C5_BURCJ
Original site: B4E8C5_BURCJ 
ID   B4E8C5_BURCJ            Unreviewed;       989 AA.
AC   B4E8C5;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   27-SEP-2017, entry version 64.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00635171};
DE            Short=PEPC {ECO:0000256|HAMAP-Rule:MF_00595};
DE            Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_00595};
DE            EC=4.1.1.31 {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00635171};
GN   Name=ppc {ECO:0000256|HAMAP-Rule:MF_00595};
GN   ORFNames=BCAL2631 {ECO:0000313|EMBL:CAR52933.1};
OS   Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656
OS   / NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=216591 {ECO:0000313|EMBL:CAR52933.1, ECO:0000313|Proteomes:UP000001035};
RN   [1] {ECO:0000313|EMBL:CAR52933.1, ECO:0000313|Proteomes:UP000001035}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 /
RC   CF5610 {ECO:0000313|Proteomes:UP000001035};
RX   PubMed=18931103; DOI=10.1128/JB.01230-08;
RA   Holden M.T., Seth-Smith H.M., Crossman L.C., Sebaihia M.,
RA   Bentley S.D., Cerdeno-Tarraga A.M., Thomson N.R., Bason N.,
RA   Quail M.A., Sharp S., Cherevach I., Churcher C., Goodhead I.,
RA   Hauser H., Holroyd N., Mungall K., Scott P., Walker D., White B.,
RA   Rose H., Iversen P., Mil-Homens D., Rocha E.P., Fialho A.M.,
RA   Baldwin A., Dowson C., Barrell B.G., Govan J.R., Vandamme P.,
RA   Hart C.A., Mahenthiralingam E., Parkhill J.;
RT   "The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of
RT   cystic fibrosis patients.";
RL   J. Bacteriol. 191:261-277(2009).
CC   -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid
CC       source for the tricarboxylic acid cycle. {ECO:0000256|HAMAP-
CC       Rule:MF_00595}.
CC   -!- CATALYTIC ACTIVITY: Phosphate + oxaloacetate = H(2)O +
CC       phosphoenolpyruvate + HCO(3)(-). {ECO:0000256|HAMAP-Rule:MF_00595,
CC       ECO:0000256|SAAS:SAAS00635165}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00595, ECO:0000256|SAAS:SAAS00635164};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00595}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC       {ECO:0000256|HAMAP-Rule:MF_00595, ECO:0000256|SAAS:SAAS00635168}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AM747720; CAR52933.1; -; Genomic_DNA.
DR   STRING; 216591.BCAL2631; -.
DR   EnsemblBacteria; CAR52933; CAR52933; BCAL2631.
DR   KEGG; bcj:BCAL2631; -.
DR   eggNOG; ENOG4105CCA; Bacteria.
DR   eggNOG; COG2352; LUCA.
DR   HOGENOM; HOG000238647; -.
DR   KO; K01595; -.
DR   OMA; PWVFGWT; -.
DR   OrthoDB; POG091H040O; -.
DR   Proteomes; UP000001035; Chromosome 1.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; SSF51621; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation {ECO:0000256|HAMAP-Rule:MF_00595,
KW   ECO:0000256|SAAS:SAAS00635173};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001035};
KW   Lyase {ECO:0000256|HAMAP-Rule:MF_00595,
KW   ECO:0000256|SAAS:SAAS00635169};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_00595,
KW   ECO:0000256|SAAS:SAAS00635157};
KW   Pyruvate {ECO:0000313|EMBL:CAR52933.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001035}.
FT   ACT_SITE    199    199       {ECO:0000256|HAMAP-Rule:MF_00595,
FT                                ECO:0000256|PROSITE-ProRule:PRU10111}.
FT   ACT_SITE    641    641       {ECO:0000256|HAMAP-Rule:MF_00595,
FT                                ECO:0000256|PROSITE-ProRule:PRU10112}.
SQ   SEQUENCE   989 AA;  108725 MW;  370D3D999DCE0012 CRC64;
     MPSPDAPTGT LATAANGRAK TATKPKDPIH QTKPATKAAG APARKAVAPK AGTRTRDDKD
     GPLFEDIRFL GRLLGDVVRE QEGDTVFDVV ETIRQTAVKF RREDDSEAAQ TLEKKLRKLT
     PEQTVSVVRA FSYFSHLANI AEDRHHNRRR RIHALAGSAP QPGTVAYALD QLKTTGNASK
     RLLQRFFDDA LIVPVLTAHP TEVQRKSILD AQHDIARLLA ERDQELTARE RQYNEAMLRA
     RVTALWQTRM LRDSRLTVGD EIENALSYYR ATFLDELPAL YGDIEAALAE HGLSARVPAF
     FQMGSWIGGD RDGNPNVTAA TLDEAINRQA AVILEHYLEQ VHKLGAELSV SNLLVGANDA
     VKALAAASPD QSPHRVDEPY RRALIGIYTR LAASARVRLG EGTVPVRSAG RGAPPVRAIP
     YEDSEAFVAD LKVLTASLDE HHGASLAAPR LAPLVRAAEV FGFHLASIDL RQSSDIHEAV
     VAELFARAGV EADYAALAEE DKLRVLLAAL ADPRPLRSPY LEYSALAQSE LGVFEKAREV
     RTQFGARAVR NYIISHTETV SDLVEVLLLQ KETGLLEGTL GVPGRDAKNS LMVIPLFETI
     PDLRDASRIM RDYFALPGID ALIAHQGAEQ EVMLGYSDSN KDGGFLTSNW ELYRAELALV
     DLFRERKITL RLFHGRGGTV GRGGGPTYQA ILSQPPGTVN GQIRLTEQGE VIASKFSNPS
     IGRRNLETVV AATLEASLLP QSNAPAQLPA FEAAMQTLSD SAMAAYRALV YETPGFTDYF
     FSSTPITEIA ELNIGSRPAS RKLQDPKQRK IEDLRAIPWG FSWGQCRLLL TGWYGFGSAV
     SAYLDGAPDA AERTKRVTLL KKMNKTWPFF SNLLSNMDMV LAKTDLAVAS RYAQLVSDRK
     LRKHVFERIV AEWERTSQAL AEITGHEGRL ATNPLLARSI KNRFPYLDPL NHLQVELIKR
     HRAGDTNARL RRGIHLTING IAAGLRNTG
//
DBGET integrated database retrieval system