ID B4H718_DROPE Unreviewed; 124 AA.
AC B4H718;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 29-MAY-2013, entry version 28.
DE RecName: Full=V-type proton ATPase subunit F;
GN Name=Dper\GL11862; ORFNames=Dper_GL11862, GL11862;
OS Drosophila persimilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;
OC Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7234;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MSH-3 / Tucson 14011-0111.49;
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- FUNCTION: Subunit of the peripheral V1 complex of vacuolar ATPase
CC essential for assembly or catalytic function. V-ATPase is
CC responsible for acidifying a variety of intracellular compartments
CC in eukaryotic cells (By similarity).
CC -!- SUBUNIT: V-ATPase is an heteromultimeric enzyme composed of a
CC peripheral catalytic V1 complex (components A to H) attached to an
CC integral membrane V0 proton pore complex (By similarity).
CC -!- SIMILARITY: Belongs to the V-ATPase F subunit family.
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DR EMBL; CH479216; EDW33654.1; -; Genomic_DNA.
DR RefSeq; XP_002026685.1; XM_002026649.1.
DR ProteinModelPortal; B4H718; -.
DR EnsemblMetazoa; FBtr0177477; FBpp0175969; FBgn0149470.
DR GeneID; 6601565; -.
DR KEGG; dpe:Dper_GL11862; -.
DR FlyBase; FBgn0149470; Dper\GL11862.
DR KO; K02151; -.
DR OrthoDB; EOG4J0ZRN; -.
DR GO; GO:0033180; C:proton-transporting V-type ATPase, V1 domain; IEA:InterPro.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR Gene3D; 3.40.50.10580; -; 1.
DR InterPro; IPR008218; ATPase_V1-cplx_f_g_su.
DR InterPro; IPR005772; ATPase_V1-cplx_fsu_euk.
DR PANTHER; PTHR13861; PTHR13861; 1.
DR Pfam; PF01990; ATP-synt_F; 1.
DR PIRSF; PIRSF015945; ATPase_V1_F_euk; 1.
DR TIGRFAMs; TIGR01101; V_ATP_synt_F; 1.
PE 3: Inferred from homology;
KW Complete proteome; Hydrogen ion transport; Ion transport; Transport.
SQ SEQUENCE 124 AA; 13876 MW; 1D91B2381D091F83 CRC64;
MALHSAIKGK LISVIGDEDT CVGFLLGGVG EINKNRHPNF MVVDKNTPVS ELEDCFKRFL
KRDDIDIILI NQNCAELIRH VIDAHTSPVP AVLEIPSKDH PYDASKDSIL RRARGMFNPE
DLVR
//