ID   B4M1S6_DROVI            Unreviewed;      1657 AA.
AC   B4M1S6;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   06-MAR-2013, entry version 34.
DE   SubName: Full=GJ18794;
GN   Name=GJ18794; Synonyms=Dvir\GJ18794; ORFNames=Dvir_GJ18794;
OS   Drosophila virilis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila.
OX   NCBI_TaxID=7244;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15010-1051.87;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the peptidase S8 family.
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DR   EMBL; CH940651; EDW65630.1; -; Genomic_DNA.
DR   RefSeq; XP_002055429.1; XM_002055393.1.
DR   ProteinModelPortal; B4M1S6; -.
DR   MEROPS; S08.049; -.
DR   EnsemblMetazoa; FBtr0234719; FBpp0233211; FBgn0205942.
DR   GeneID; 6631484; -.
DR   KEGG; dvi:Dvir_GJ18794; -.
DR   FlyBase; FBgn0205942; Dvir\GJ18794.
DR   eggNOG; COG4935; -.
DR   InParanoid; B4M1S6; -.
DR   OMA; FKPWYLE; -.
DR   OrthoDB; EOG4MPG51; -.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.200; -; 1.
DR   InterPro; IPR000742; EG-like_dom.
DR   InterPro; IPR006212; Furin_repeat.
DR   InterPro; IPR008979; Galactose-bd-like.
DR   InterPro; IPR009030; Growth_fac_rcpt.
DR   InterPro; IPR000209; Peptidase_S8/S53_dom.
DR   InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR   InterPro; IPR022398; Peptidase_S8_His-AS.
DR   InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR   InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR   InterPro; IPR009020; Prot_inh_propept.
DR   InterPro; IPR002884; PrprotnconvertsP.
DR   PANTHER; PTHR10795; PTHR10795; 1.
DR   Pfam; PF01483; P_proprotein; 1.
DR   Pfam; PF00082; Peptidase_S8; 1.
DR   PRINTS; PR00723; SUBTILISIN.
DR   SMART; SM00181; EGF; 1.
DR   SMART; SM00261; FU; 10.
DR   SUPFAM; SSF49785; Gal_bind_like; 1.
DR   SUPFAM; SSF57184; Grow_fac_recept; 4.
DR   SUPFAM; SSF52743; Pept_S8_S53; 1.
DR   SUPFAM; SSF54897; Prot_inh_propept; 1.
DR   PROSITE; PS00136; SUBTILASE_ASP; 1.
DR   PROSITE; PS00137; SUBTILASE_HIS; 1.
DR   PROSITE; PS00138; SUBTILASE_SER; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Protease; Repeat; Serine protease.
SQ   SEQUENCE   1657 AA;  182325 MW;  8D4321CF14F90D81 CRC64;
     MLDIGIGKRT VELPFIVERT CTDCANDNNN LRPETEAEAE ADTEADRSSA TSRSTLPNQL
     SINICSKKPG KGTASRCHPY VKLNRRIYLR KCNRMATSCI YFVLVLAILS LRNTSAAFHN
     NITNNSINNY YNNNNIESVS KTQHSAGILR INESASEFYP INNYSKYQQY SKTELTGNRK
     SKHPALIIAE TDSEASNTHN NNTNNASAKK QTEKNVEQTE KHHLDDIDIF GAYSIPDDPI
     YTNEFAVHIP AGKYVADSIA GKYGFTNKGQ IGALDDYYLF QHHRVSKRSL RSSRKHHSAL
     KSEFEVKWLQ QQHEKIRRKR DGPYQDIPTY SPYNILRQTN DYLIDPHTNT HFSYSPDPVL
     TSSLVGTHSP RLEYRDVTSH LIFSDPLFKE QWYLNGGAKD GLDMNIGPAW QKGYTGKGVV
     VSILDDGIQT NHPDLAQNYD PDASFDINGN DSDPTPQDNG DNKHGTRCAG EVAAVAFNNY
     CGVGVAYNAS IGGVRMLDGK VNDVVEAQAL SLNPSHIDIY SASWGPEDDG STVDGPGPLA
     RRAFIYGVTS GRQGKGSIFV WASGNGGRYT DSCNCDGYTN SIFTLSISSA TQAGFKPWYL
     EECSSTLATT YSSGTPGHDK SVATVDMDGR LRPDHICTVE HTGTSASAPL AAGICALALE
     ANPGITWRDM QYLVVYTSRP GPLEKESGWT LNGVKRKYSH KFGYGLMDAG AMVALAEQWN
     SVPPQHICKS RENNEDRKIE GAYGYTLATH MDVNGCAGTI NEVRYLEHVQ CRITLRFFPR
     GNLRILLTSP MGTTSTLLFE RPRDIVKSNF DDWPFLSVHY WGEKAEGRWT LQVINGGRRR
     VNQPGILSKW QLIFYGTSTQ PMRLKSELLN TQLRNSPIAN NPFIFSSASN IGQPANEGGN
     FNTDNFASYL NYQNIFSSAG SSPEVATATL DGHNVSTTTS AQLSNALPNG DNKLILYSCD
     AECDSLGCYG RGPTQCVACS HYRLDNTCVS RCPPRSFPNQ VGICWPCHDS CETCAGAGPD
     SCLTCAPAHL HVTDLAVCLQ VCPDGYFEDV KNRTCVPCEP NCASCQDRPE YCTSCDHHLV
     MHENKCYSAC PLNTFETEEN KCTYCHSSCA TCNGATENNC ITCRPSRYAW QNKCLNNCPD
     GFYADKKRLE CLPCHEGCKS CSSNGICTEC LPNWTLNKKD KCIVAGSESC FESEYYSQSE
     GKCNPCHDSC ETCNGPMSSN CLSCHQNRLL EQSSCVSGCQ DGFYMETGVC TPCLHTCTQC
     VSRTNCSNCS KGLELQNGEC RTTCADGYYS DRGICAKCYL SCHTCSGPRR NQCVHCPAGW
     QLAAGECHPE CPEGFYKSDF GCQKCHHYCK TCNGAGPLAC SSCPTHFMLD GGLCMECLSS
     QYYDTTTQTC KSCHESCRSC FGPGQYSCKA CAPPLHLDQL NSQCVPCCQN KSAGDNETGS
     ENCCHCDKDT GECKTVSTAG KRRTVVGSDS IFRNMDRAAI NDEGNSGSFA LRLDSPLTAI
     TAIAVAICLL IITIFSIIFA VLQRNSNHVS RNSVRYRKII SKSGGRKSDP SNEARFIFNV
     GDDGDDTEDN TDDDLDVHTR AIKKVVYEPN GPMNGNEFFI KSTNDIDAVE FHCKGAGVNK
     SKFDTQRNAN TNHTECSSPT YMNQATTSRM NSKIVHS
//