ID   B4TQM0_SALSV            Unreviewed;       534 AA.
AC   B4TQM0;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   01-MAY-2013, entry version 38.
DE   RecName: Full=Malate synthase;
DE            EC=2.3.3.9;
GN   Name=aceB; OrderedLocusNames=SeSA_A4394;
OS   Salmonella schwarzengrund (strain CVM19633).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=439843;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CVM19633;
RA   Ravel J., Fricke W.F., White D., McDermott P., Mammel M., Rosovitz M.,
RA   Leclerc J., Cebula T., Sebastian Y.;
RT   "Complete genome of Salmonella schwarzengrund strain CVM19633.";
RL   Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Acetyl-CoA + H(2)O + glyoxylate = (S)-malate +
CC       CoA.
CC   -!- PATHWAY: Carbohydrate metabolism; glyoxylate cycle; (S)-malate
CC       from isocitrate: step 2/2.
CC   -!- SIMILARITY: Belongs to the malate synthase family.
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DR   EMBL; CP001127; ACF91332.1; -; Genomic_DNA.
DR   RefSeq; YP_002117081.1; NC_011094.1.
DR   ProteinModelPortal; B4TQM0; -.
DR   STRING; 439843.SeSA_A4394; -.
DR   EnsemblBacteria; ACF91332; ACF91332; SeSA_A4394.
DR   GeneID; 6518587; -.
DR   KEGG; sew:SeSA_A4394; -.
DR   PATRIC; 32377347; VBISalEnt87589_4353.
DR   eggNOG; COG2225; -.
DR   HOGENOM; HOG000238464; -.
DR   KO; K01638; -.
DR   OMA; GFDGTWV; -.
DR   ProtClustDB; PRK09255; -.
DR   BioCyc; SENT439843:GHHR-2793-MONOMER; -.
DR   UniPathway; UPA00703; UER00720.
DR   GO; GO:0004474; F:malate synthase activity; IEA:EC.
DR   GO; GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
DR   InterPro; IPR011076; Malate_synth-like.
DR   InterPro; IPR006252; Malate_synthA.
DR   InterPro; IPR001465; Malate_synthase.
DR   InterPro; IPR019830; Malate_synthase_CS.
DR   PANTHER; PTHR21631:SF1; PTHR21631:SF1; 1.
DR   Pfam; PF01274; Malate_synthase; 1.
DR   PIRSF; PIRSF001363; Malate_synth; 1.
DR   SUPFAM; SSF51645; Malat_synth_like; 1.
DR   TIGRFAMs; TIGR01344; malate_syn_A; 1.
DR   PROSITE; PS00510; MALATE_SYNTHASE; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Complete proteome; Glyoxylate bypass; Transferase;
KW   Tricarboxylic acid cycle.
FT   ACT_SITE    167    167       Proton acceptor (By similarity).
FT   ACT_SITE    448    448       Proton donor (By similarity).
SQ   SEQUENCE   534 AA;  60558 MW;  87554C676E305DA6 CRC64;
     MMNPQATTTD ELTFTRPQGE LEKQVLTAEA VEFLTELVTR FTPKRNKLLA ARIQQQQDID
     NGKLPDFISE TTSIRESNWQ IRGIPADLQD RRVEITGPVE RKMVINALNA NVKVFMADFE
     DSLAPDWNKV MDGQINLRDA VNGTISYTNE AGKIYQLKPD PAVLICRVRG LHLPEKHVTW
     RGEAIPGSLF DFALYFFHNY KALLAKGSGP YFYLPKTQAW QEAAWWSEVF SYAEDRFNLP
     RGTIKATLLI ETLPAVFQMD EILHALRDHI VGLNCGRWDY IFSYIKTLKN YPDRVLPDRQ
     VVTMDKPFLS AYSRLLIKTC HKRGAFAMGG MAAFIPSKDV ERNNQVLAKV KADKALEANN
     GHDGTWIAHP GLADTAMAVF NEVLGEHKNQ LFITRDEDAP ITAEQLLEPC EGERTEAGMR
     ANIRVAVQYI EAWISGNGCV PIYGLMEDAA TAEISRTSIW QWIHHEKTLS NGKPVTKTLF
     REMLAEEMRV IQDELGEHRY SSGRFDDAAR LMEQITTSDD LIDFLTLPGY RLLA
//