GenomeNet

Database: UniProt/TrEMBL
Entry: B6HPQ4_PENRW
LinkDB: B6HPQ4_PENRW
Original site: B6HPQ4_PENRW 
ID   B6HPQ4_PENRW            Unreviewed;       512 AA.
AC   B6HPQ4;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   25-OCT-2017, entry version 57.
DE   RecName: Full=Glutamate decarboxylase {ECO:0000256|RuleBase:RU361171};
DE            EC=4.1.1.15 {ECO:0000256|RuleBase:RU361171};
GN   ORFNames=Pc22g00970 {ECO:0000313|EMBL:CAP97385.1}, PCH_Pc22g00970
GN   {ECO:0000313|EMBL:CAP97385.1};
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 /
OS   Wisconsin 54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP97385.1, ECO:0000313|Proteomes:UP000000724};
RN   [1] {ECO:0000313|EMBL:CAP97385.1, ECO:0000313|Proteomes:UP000000724}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC   {ECO:0000313|Proteomes:UP000000724};
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A.,
RA   van der Klei I.J., van Peij N.N.M.E., Veenhuis M., von Doehren H.,
RA   Wagner C., Wortman J.R., Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- CATALYTIC ACTIVITY: L-glutamate = 4-aminobutanoate + CO(2).
CC       {ECO:0000256|RuleBase:RU361171}.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602129-50,
CC         ECO:0000256|RuleBase:RU361171};
CC   -!- SIMILARITY: Belongs to the group II decarboxylase family.
CC       {ECO:0000256|RuleBase:RU361171}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AM920437; CAP97385.1; -; Genomic_DNA.
DR   RefSeq; XP_002564142.1; XM_002564096.1.
DR   ProteinModelPortal; B6HPQ4; -.
DR   STRING; 500485.XP_002564142.1; -.
DR   EnsemblFungi; CAP97385; CAP97385; PCH_Pc22g00970.
DR   GeneID; 8306589; -.
DR   KEGG; pcs:Pc22g00970; -.
DR   eggNOG; KOG1383; Eukaryota.
DR   eggNOG; COG0076; LUCA.
DR   HOGENOM; HOG000070228; -.
DR   KO; K01580; -.
DR   OMA; FTTSVYG; -.
DR   OrthoDB; EOG092C1P0W; -.
DR   BioCyc; PCHR:PC22G00970-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c22.
DR   GO; GO:0004351; F:glutamate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006536; P:glutamate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 1.
DR   InterPro; IPR010107; Glutamate_decarboxylase.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major_sub1.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_sub2.
DR   PANTHER; PTHR43321; PTHR43321; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   TIGRFAMs; TIGR01788; Glu-decarb-GAD; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000724};
KW   Decarboxylase {ECO:0000256|RuleBase:RU361171};
KW   Lyase {ECO:0000256|RuleBase:RU361171};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50,
KW   ECO:0000256|RuleBase:RU361171};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000724}.
FT   MOD_RES     292    292       N6-(pyridoxal phosphate)lysine.
FT                                {ECO:0000256|PIRSR:PIRSR602129-50}.
SQ   SEQUENCE   512 AA;  58546 MW;  8BE7B1FF18515D1C CRC64;
     MVHLAKVKKD NEVPPSTHDI VSVAPPDIDD FETNVYGSHF AADHMPLHEM PEREMPRQIA
     ARMIKDELSL DGNPKLNLAS FVTTYMEDEI EQIMTESFSK NFIDYEEYPH SAEIQNRCVN
     MIARLFHIPT DASGENAMGT STIGSSEAIM LGTLAMKKRW QNKRKAEGKD YSRPNIIMNS
     AVQVCWEKAA RYFEIEEKYV YCTDTRFVID PKQAVDLVDE NTIGICAILG TTYTGEYEDI
     KAINDLLVER NIDCPIHVDA ASGGFVAPFI QPDLKWDFRL EKVVSINVSG HKYGLVYPGV
     GWVIWRSPEY LPQELVFNIN YLGADQASFT LNFSKGASHV IGQYYQLIRL GKHGYRAIMS
     NITRISDYMS SEFEKMGMVI LSQTQGRGLP LVAWRLPTDD SRIYDEFAVA HQLRERGWIV
     PAYTMAPNSE KLQMMRIVIR EDFSMHRCDS LLQDFKLAIE SLDAMDKSML DKYKTHMKNH
     RNHPRHQSRV HAHYMNEKHS LQGQTGKTHG VC
//
DBGET integrated database retrieval system