ID B7FT57_PHATC Unreviewed; 356 AA.
AC B7FT57;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 01-MAY-2013, entry version 25.
DE RecName: Full=Branched-chain-amino-acid aminotransferase;
DE EC=2.6.1.42;
GN ORFNames=PHATRDRAFT_43697;
OS Phaeodactylum tricornutum (strain CCAP 1055/1).
OC Eukaryota; Stramenopiles; Bacillariophyta; Bacillariophyceae;
OC Bacillariophycidae; Naviculales; Phaeodactylaceae; Phaeodactylum.
OX NCBI_TaxID=556484;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCAP 1055/1;
RX PubMed=18923393; DOI=10.1038/nature07410;
RA Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A.,
RA Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E.,
RA Salamov A., Vandepoele K., Beszteri B., Gruber A., Heijde M.,
RA Katinka M., Mock T., Valentin K., Verret F., Berges J.A., Brownlee C.,
RA Cadoret J.P., Chiovitti A., Choi C.J., Coesel S., De Martino A.,
RA Detter J.C., Durkin C., Falciatore A., Fournet J., Haruta M.,
RA Huysman M.J., Jenkins B.D., Jiroutova K., Jorgensen R.E., Joubert Y.,
RA Kaplan A., Kroger N., Kroth P.G., La Roche J., Lindquist E.,
RA Lommer M., Martin-Jezequel V., Lopez P.J., Lucas S., Mangogna M.,
RA McGinnis K., Medlin L.K., Montsant A., Oudot-Le Secq M.P., Napoli C.,
RA Obornik M., Parker M.S., Petit J.L., Porcel B.M., Poulsen N.,
RA Robison M., Rychlewski L., Rynearson T.A., Schmutz J., Shapiro H.,
RA Siaut M., Stanley M., Sussman M.R., Taylor A.R., Vardi A.,
RA von Dassow P., Vyverman W., Willis A., Wyrwicz L.S., Rokhsar D.S.,
RA Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y.,
RA Grigoriev I.V.;
RT "The Phaeodactylum genome reveals the evolutionary history of diatom
RT genomes.";
RL Nature 456:239-244(2008).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=CCAP 1055/1;
RG Diatom Consortium;
RA Grigoriev I., Grimwood J., Kuo A., Otillar R.P., Salamov A.,
RA Detter J.C., Lindquist E., Shapiro H., Lucas S., Glavina del Rio T.,
RA Pitluck S., Rokhsar D., Bowler C.;
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY: L-isoleucine + 2-oxoglutarate = (S)-3-methyl-
CC 2-oxopentanoate + L-glutamate.
CC -!- CATALYTIC ACTIVITY: L-leucine + 2-oxoglutarate = 4-methyl-2-
CC oxopentanoate + L-glutamate.
CC -!- CATALYTIC ACTIVITY: L-valine + 2-oxoglutarate = 3-methyl-2-
CC oxobutanoate + L-glutamate.
CC -!- COFACTOR: Pyridoxal phosphate (By similarity).
CC -!- SIMILARITY: Belongs to the class-IV pyridoxal-phosphate-dependent
CC aminotransferase family.
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DR EMBL; CM000606; EEC50596.1; -; Genomic_DNA.
DR RefSeq; XP_002177782.1; XM_002177746.1.
DR UniGene; Ptc.18448; -.
DR STRING; 2850.JGI43697; -.
DR EnsemblProtists; Phatr43697; Phatr43697; Phatr43697.
DR GeneID; 7197239; -.
DR KEGG; pti:PHATRDRAFT_43697; -.
DR HOGENOM; HOG000276704; -.
DR KO; K00826; -.
DR ProtClustDB; CLSN2700745; -.
DR GO; GO:0052656; F:L-isoleucine transaminase activity; IEA:EC.
DR GO; GO:0052654; F:L-leucine transaminase activity; IEA:EC.
DR GO; GO:0052655; F:L-valine transaminase activity; IEA:EC.
DR GO; GO:0009082; P:branched-chain amino acid biosynthetic process; IEA:UniProtKB-KW.
DR InterPro; IPR001544; Aminotrans_IV.
DR InterPro; IPR018300; Aminotrans_IV_CS.
DR InterPro; IPR005786; B_amino_transII.
DR PANTHER; PTHR11825; PTHR11825; 1.
DR PANTHER; PTHR11825:SF2; PTHR11825:SF2; 1.
DR Pfam; PF01063; Aminotran_4; 1.
DR PIRSF; PIRSF006468; BCAT1; 1.
DR SUPFAM; SSF56752; Aminotrans_IV; 1.
DR TIGRFAMs; TIGR01123; ilvE_II; 1.
DR PROSITE; PS00770; AA_TRANSFER_CLASS_4; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis; Aminotransferase;
KW Branched-chain amino acid biosynthesis; Complete proteome;
KW Pyridoxal phosphate; Reference proteome; Transferase.
FT MOD_RES 188 188 N6-(pyridoxal phosphate)lysine (By
FT similarity).
SQ SEQUENCE 356 AA; 39614 MW; B253B1B042E0CCAF CRC64;
MRSEMSKPEE LVFGTTLSDH MLMIEWSKEK NWMDPRIIPR QDLNISPAAS SLHYGIQCFE
GMKAYRSIAD DSIRLFRPDM NMKRLSSSMD RLQMPGFDFN HSQLIDCIEN LVLLDQKWIP
EGEGYSLYLR PTVIATHKFL GLAAPDSLLL FCITSPVGPY YKSGFAPIRL TTDTPYVRAW
PGGTGAAKVG GNYASTMKPQ AEAAAKGYSQ VLWLFGDDES ITEVGSMNVF FFLINKETSR
PELVTAPLDR GDILPGVTRD SILQLTRSWG EFDVSERFPT MPEIAQAAKE GRLIEAFGAG
TAAVVTPISC IEYQGNDIEI PATGKLTQRI WDEITGIQYG KIEGPEGWSI PIGDHQ
//
