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Database: UniProt/TrEMBL
Entry: B7J452_ACIF2
LinkDB: B7J452_ACIF2
Original site: B7J452_ACIF2 
ID   B7J452_ACIF2            Unreviewed;       396 AA.
AC   B7J452;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   11-JUN-2014, entry version 42.
DE   RecName: Full=Elongation factor Tu;
DE            Short=EF-Tu;
GN   Name=tuf-2; Synonyms=tuf, tuf-1; OrderedLocusNames=AFE_0311, AFE_0325;
OS   Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / NCIB
OS   8455) (Ferrobacillus ferrooxidans (strain ATCC 23270)).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Acidithiobacillales;
OC   Acidithiobacillaceae; Acidithiobacillus.
OX   NCBI_TaxID=243159;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23270, and ATCC 23270 / DSM 14882 / NCIB 8455;
RX   PubMed=19077236; DOI=10.1186/1471-2164-9-597;
RA   Valdes J., Pedroso I., Quatrini R., Dodson R.J., Tettelin H.,
RA   Blake R.II., Eisen J.A., Holmes D.S.;
RT   "Acidithiobacillus ferrooxidans metabolism: from genome sequence to
RT   industrial applications.";
RL   BMC Genomics 9:597-597(2008).
CC   -!- FUNCTION: This protein promotes the GTP-dependent binding of
CC       aminoacyl-tRNA to the A-site of ribosomes during protein
CC       biosynthesis (By similarity).
CC   -!- SUBUNIT: Monomer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the GTP-binding elongation factor family.
CC       EF-Tu/EF-1A subfamily.
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DR   EMBL; CP001219; ACK77993.1; -; Genomic_DNA.
DR   EMBL; CP001219; ACK78942.1; -; Genomic_DNA.
DR   RefSeq; YP_002424815.1; NC_011761.1.
DR   RefSeq; YP_002424828.1; NC_011761.1.
DR   STRING; 243159.AFE_0325; -.
DR   EnsemblBacteria; ACK77993; ACK77993; AFE_0311.
DR   EnsemblBacteria; ACK78942; ACK78942; AFE_0325.
DR   GeneID; 7136011; -.
DR   GeneID; 7136844; -.
DR   KEGG; afr:AFE_0311; -.
DR   KEGG; afr:AFE_0325; -.
DR   PATRIC; 20651957; VBIAciFer29821_0300.
DR   eggNOG; COG0050; -.
DR   HOGENOM; HOG000229290; -.
DR   KO; K02358; -.
DR   OMA; GTEMCMP; -.
DR   OrthoDB; EOG6R5C6X; -.
DR   BioCyc; AFER243159:GH3S-311-MONOMER; -.
DR   BioCyc; AFER243159:GH3S-325-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-HAMAP.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00118_B; EF_Tu_B; 1.
DR   InterPro; IPR000795; EF_GTP-bd_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   InterPro; IPR004161; Transl_elong_EFTu/EF1A_2.
DR   InterPro; IPR004541; Transl_elong_EFTu/EF1A_bac/org.
DR   InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF03144; GTP_EFTU_D2; 1.
DR   Pfam; PF03143; GTP_EFTU_D3; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   SUPFAM; SSF50465; SSF50465; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00485; EF-Tu; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS00301; EFACTOR_GTP; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Elongation factor; GTP-binding;
KW   Nucleotide-binding; Protein biosynthesis.
FT   NP_BIND      19     26       GTP (By similarity){EA7}.
FT   NP_BIND      81     85       GTP (By similarity){EA7}.
FT   NP_BIND     136    139       GTP (By similarity){EA7}.
SQ   SEQUENCE   396 AA;  43179 MW;  C487F76D11C7564B CRC64;
     MSKGKFERTK PHVNVGTIGH VDHGKTTLTA ALTKVLSAKF GGEIRAYDQI DNAPEERARG
     ITIATSHVEY ETANRHYAHV DCPGHADYVK NMITGAAQMD GAILVCSAAD GPMPQTREHI
     LLARQVGVPY IVVFLNKADM VDDAELLELV EMEVRELLSK YEFPGDDIPV IIGSALKALE
     GDQSDIGEPA IFRLADAMDS YIPMPERPVD KPFLMPIEDV FSISGRGTVV TGRIERGIVK
     IGDEIEIIGI HNTAKSIVTG VEMFRKILDQ GQAGDNVGVL LRGTKKDDVE RGQVLAKPGS
     IKPHTRFEAE VYVLSKEEGG RHTPFFNGYR PQFYFRTTDV TGAVELPEGV EMVMPGDNIL
     FKVALIAPIA MEEGLRFAVR EGGRTVGAGV VSKVVE
//
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