GenomeNet

Database: UniProt/TrEMBL
Entry: B7KD89_CYAP7
LinkDB: B7KD89_CYAP7
Original site: B7KD89_CYAP7 
ID   B7KD89_CYAP7            Unreviewed;       436 AA.
AC   B7KD89;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   25-OCT-2017, entry version 59.
DE   RecName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex {ECO:0000256|RuleBase:RU003423};
DE            EC=2.3.1.- {ECO:0000256|RuleBase:RU003423};
GN   OrderedLocusNames=PCC7424_0443 {ECO:0000313|EMBL:ACK68909.1};
OS   Cyanothece sp. (strain PCC 7424) (Synechococcus sp. (strain ATCC
OS   29155)).
OC   Bacteria; Cyanobacteria; Oscillatoriophycideae; Oscillatoriales;
OC   Cyanothecaceae; Cyanothece.
OX   NCBI_TaxID=65393 {ECO:0000313|EMBL:ACK68909.1, ECO:0000313|Proteomes:UP000002384};
RN   [1] {ECO:0000313|Proteomes:UP000002384}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7424 {ECO:0000313|Proteomes:UP000002384};
RX   PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M.,
RA   Min H., Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a
RT   group of unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
CC   -!- COFACTOR:
CC       Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC         Evidence={ECO:0000256|RuleBase:RU003423};
CC   -!- SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003423}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001291; ACK68909.1; -; Genomic_DNA.
DR   RefSeq; WP_012597856.1; NC_011729.1.
DR   ProteinModelPortal; B7KD89; -.
DR   STRING; 65393.PCC7424_0443; -.
DR   EnsemblBacteria; ACK68909; ACK68909; PCC7424_0443.
DR   KEGG; cyc:PCC7424_0443; -.
DR   eggNOG; ENOG4107UKP; Bacteria.
DR   eggNOG; COG0508; LUCA.
DR   HOGENOM; HOG000281566; -.
DR   KO; K00627; -.
DR   OMA; TMEFESF; -.
DR   OrthoDB; POG091H04EL; -.
DR   Proteomes; UP000002384; Chromosome.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; IEA:InterPro.
DR   Gene3D; 4.10.320.10; -; 1.
DR   InterPro; IPR003016; 2-oxoA_DH_lipoyl-BS.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR004167; E3-bd.
DR   InterPro; IPR036625; E3-bd_dom_sf.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   Pfam; PF00364; Biotin_lipoyl; 1.
DR   Pfam; PF02817; E3_binding; 1.
DR   SUPFAM; SSF47005; SSF47005; 1.
DR   SUPFAM; SSF51230; SSF51230; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR   PROSITE; PS00189; LIPOYL; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003423};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002384};
KW   Lipoyl {ECO:0000256|RuleBase:RU003423, ECO:0000256|SAAS:SAAS00100674};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002384};
KW   Transferase {ECO:0000256|RuleBase:RU003423}.
FT   DOMAIN        2     77       Lipoyl-binding. {ECO:0000259|PROSITE:
FT                                PS50968}.
SQ   SEQUENCE   436 AA;  45555 MW;  23EFF2ED36F43983 CRC64;
     MIHDIFMPAL SSTMTEGKIV SWVKSPGDKV VKGETVVVVE SDKADMDVES FFDGYLAVII
     VNAGEEAPVG APIALVAETE AEIQQAQAQA SSGQASAPAP QEAQPAPEPA MAAFASTPAS
     SNAGSSAPSQ TNGRLVASPR AKKLAKELGV DLKTIRGSGP HGRITGEDVE QAVGKAPQPA
     AQPISAPVSA PTPQPTPQPA PVPAVAAPVS VAPGEVVPFN TLQKAVVQNM MASMQAPMFR
     VGYTITTDAL DDLYKKVKSK GVTMSALLAK AVALSLQKHP VVNASYTEKG IQYNSSINIA
     VAVAMPDGGL ITPVLRNADQ TDLYSLSRQW KDLVDRARAK QLQPEEYSTG TFTISNLGMF
     GVDRFDAILP VGQGSILAIG ASRPQVVATP EGLLGVKRQM TVNITCDHRI IYGADAAGFL
     QDLAKIIETD PQSLTL
//
DBGET integrated database retrieval system