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Database: UniProt/TrEMBL
Entry: B7QJ45_IXOSC
LinkDB: B7QJ45_IXOSC
Original site: B7QJ45_IXOSC 
ID   B7QJ45_IXOSC            Unreviewed;       900 AA.
AC   B7QJ45;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   22-NOV-2017, entry version 52.
DE   SubName: Full=Histone deacetylase 4, 5, putative {ECO:0000313|EMBL:EEC18867.1};
DE   SubName: Full=Histone deacetylase 4, 5, putative (Fragment) {ECO:0000313|VectorBase:ISCW014481-PA};
DE   Flags: Fragment;
GN   Name=8042022 {ECO:0000313|VectorBase:ISCW014481-PA};
GN   ORFNames=IscW_ISCW014481 {ECO:0000313|EMBL:EEC18867.1};
OS   Ixodes scapularis (Black-legged tick) (Deer tick).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX   NCBI_TaxID=6945 {ECO:0000313|Proteomes:UP000001555};
RN   [1] {ECO:0000313|EMBL:EEC18867.1, ECO:0000313|Proteomes:UP000001555, ECO:0000313|VectorBase:ISCW014481-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555,
RC   ECO:0000313|VectorBase:ISCW014481-PA}, and Wikel colony
RC   {ECO:0000313|EMBL:EEC18867.1};
RG   Ixodes scapularis Genome Project Consortium;
RA   Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M.,
RA   Amedeo P., Galinsky K.J., Schobel S., Inman J., Hostetler J.,
RA   Miller J., Hammond M., Megy K., Lawson D., Kodira C., Sutton G.,
RA   Meyer J., Hill C.A., Birren B., Nene V., Collins F.,
RA   Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT   "Annotation of Ixodes scapularis.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:ISCW014481-PA}
RP   IDENTIFICATION.
RC   STRAIN=wikel {ECO:0000313|VectorBase:ISCW014481-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   EMBL; ABJB010169211; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010328554; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010745128; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010885265; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010897877; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB011097328; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB011126718; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DS949579; EEC18867.1; -; Genomic_DNA.
DR   RefSeq; XP_002415202.1; XM_002415157.1.
DR   ProteinModelPortal; B7QJ45; -.
DR   STRING; 6945.ISCW014481-PA; -.
DR   EnsemblMetazoa; ISCW014481-RA; ISCW014481-PA; ISCW014481.
DR   GeneID; 8042022; -.
DR   KEGG; isc:IscW_ISCW014481; -.
DR   VectorBase; ISCW014481-RA; ISCW014481-PA; ISCW014481.
DR   CTD; 8042022; -.
DR   eggNOG; KOG1343; Eukaryota.
DR   eggNOG; COG0123; LUCA.
DR   InParanoid; B7QJ45; -.
DR   KO; K11406; -.
DR   OMA; DSQKFFS; -.
DR   OrthoDB; EOG091G0EQO; -.
DR   Proteomes; UP000001555; Unassembled WGS sequence.
DR   GO; GO:0000118; C:histone deacetylase complex; IEA:InterPro.
DR   GO; GO:0004407; F:histone deacetylase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.800.20; -; 1.
DR   InterPro; IPR033660; HDAC4.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR017320; Histone_deAcase_II_euk.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   PANTHER; PTHR10625; PTHR10625; 1.
DR   PANTHER; PTHR10625:SF100; PTHR10625:SF100; 1.
DR   Pfam; PF00850; Hist_deacetyl; 1.
DR   PIRSF; PIRSF037911; HDAC_II_euk; 1.
DR   PRINTS; PR01270; HDASUPER.
DR   SUPFAM; SSF52768; SSF52768; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001555};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR037911-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW   Zinc {ECO:0000256|PIRSR:PIRSR037911-2}.
FT   DOMAIN      507    822       Hist_deacetyl. {ECO:0000259|Pfam:
FT                                PF00850}.
FT   ACT_SITE    634    634       {ECO:0000256|PIRSR:PIRSR037911-1}.
FT   METAL       499    499       Zinc. {ECO:0000256|PIRSR:PIRSR037911-2}.
FT   METAL       501    501       Zinc. {ECO:0000256|PIRSR:PIRSR037911-2}.
FT   METAL       507    507       Zinc. {ECO:0000256|PIRSR:PIRSR037911-2}.
FT   METAL       582    582       Zinc. {ECO:0000256|PIRSR:PIRSR037911-2}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:EEC18867.1}.
SQ   SEQUENCE   900 AA;  98297 MW;  7275BECF711E9AEA CRC64;
     GAIASSEVKQ RLQEFVLSKK QREAAANSAN TSPPNFRNWS RQRSSLDQAS PPSTSAVSPQ
     CRHPLLGKYD DDFPLRKTAS EPNLKVRSVL KQKVIERRSS PLLRRKDKGP VPLKRRPLTS
     RHPFLLFLSP HSPSVPSSCN HLLQNLLVLW FFPQEPGNSP YHPLSQGGTN DLTLYSSPSM
     PNISLGRPPV PSSSAVSLPL CPAHVFYGLK RAISYVTQDG KILNSVSEAQ VRAMAAARLG
     MPLTSHVLHS SLPFCSPLPG SPSLGSPIVL PRSALLWWGL TVPPLCFRTI HRPLGRTQSA
     PLPLGHPMLQ PQGVLINAQL YEQQQQHNLL KQHIRQTVLT RAGSKSQVVE HVEEETEAAV
     AQEMKDQPEV IDLTDTRKAP SSENPLDPPT LLLLQRQQQR DLVARHSLHN SSWVVESPTW
     VQHAGSAFTP RHPHGHHGAR PLSRALSSPL VSLSPPGGSP QTQQQEAATM GNPGAAPGSS
     PPRVTTGLAY DSLMLKHQCI CGDYSSHPEH GGRLQSIWAR LQETGLAARC ERIRSRKATL
     EEIQSCHDEG YAFMFGTNPL NRQKLEMSKL ELPIKSFVML PCGGIGVDSD TTWNELHTAS
     AARMATGCVI ELSFKVATGE AKNGFAMVRP PGHHAEFKQA MGFCFFNSVA IAAKQLRQKL
     KMEKILVIDW DVHHGNGLQQ IFYDDPHVLY VSLHRHDDGN FFPGTGDPQE VGVEDGTGFN
     VNIAWSGTLN PPMGDAEYIA AFRTIVMPIA RDFDPEIVLV AAGFDAAAGH PPPLGGYQIS
     PACFAYMTKQ LMTLAKGKVV LALEGGYDLP SICDCSQECV AALLGDEVSP LREEEVTRQP
     CGAAVQVLQR TAAIQAPHWP CIKKWAPTIG SSLLDAQQKD KEEVETVTAL ASLSMAVQMQ
//
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