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Database: UniProt/TrEMBL
Entry: B8NPD5_ASPFN
LinkDB: B8NPD5_ASPFN
Original site: B8NPD5_ASPFN 
ID   B8NPD5_ASPFN            Unreviewed;       490 AA.
AC   B8NPD5;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   05-JUL-2017, entry version 58.
DE   RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE            EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN   ORFNames=AFLA_130070 {ECO:0000313|EMBL:EED48784.1};
OS   Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM
OS   12722 / SRRC 167).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=332952 {ECO:0000313|EMBL:EED48784.1, ECO:0000313|Proteomes:UP000001875};
RN   [1] {ECO:0000313|EMBL:EED48784.1, ECO:0000313|Proteomes:UP000001875}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167
RC   {ECO:0000313|Proteomes:UP000001875};
RX   PubMed=25883274; DOI=10.1128/genomeA.00168-15;
RA   Nierman W.C., Yu J., Fedorova-Abrams N.D., Losada L., Cleveland T.E.,
RA   Bhatnagar D., Bennett J.W., Dean R., Payne G.A.;
RT   "Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes
RT   aflatoxin contamination of food and feed.";
RL   Genome Announc. 3:E0016815-E0016815(2015).
CC   -!- SIMILARITY: Belongs to the hexokinase family.
CC       {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672880}.
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DR   EMBL; EQ963481; EED48784.1; -; Genomic_DNA.
DR   RefSeq; XP_002382200.1; XM_002382159.1.
DR   ProteinModelPortal; B8NPD5; -.
DR   STRING; 5059.CADAFLAP00010065; -.
DR   PRIDE; B8NPD5; -.
DR   EnsemblFungi; EED48784; EED48784; AFLA_130070.
DR   GeneID; 7913704; -.
DR   KEGG; afv:AFLA_130070; -.
DR   EuPathDB; FungiDB:AFLA_130070; -.
DR   HOGENOM; HOG000162670; -.
DR   KO; K00844; -.
DR   OMA; ERQFFRA; -.
DR   OrthoDB; EOG092C2JW4; -.
DR   Proteomes; UP000001875; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR   GO; GO:0005634; C:nucleus; IEA:EnsemblFungi.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008865; F:fructokinase activity; IEA:EnsemblFungi.
DR   GO; GO:0004340; F:glucokinase activity; IEA:EnsemblFungi.
DR   GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR   GO; GO:0019158; F:mannokinase activity; IEA:EnsemblFungi.
DR   GO; GO:0001678; P:cellular glucose homeostasis; IEA:InterPro.
DR   GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:EnsemblFungi.
DR   GO; GO:0006000; P:fructose metabolic process; IEA:EnsemblFungi.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:EnsemblFungi.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:EnsemblFungi.
DR   InterPro; IPR001312; Hexokinase.
DR   InterPro; IPR019807; Hexokinase_BS.
DR   InterPro; IPR022673; Hexokinase_C.
DR   InterPro; IPR022672; Hexokinase_N.
DR   PANTHER; PTHR19443; PTHR19443; 1.
DR   Pfam; PF00349; Hexokinase_1; 1.
DR   Pfam; PF03727; Hexokinase_2; 1.
DR   PROSITE; PS00378; HEXOKINASE_1; 1.
DR   PROSITE; PS51748; HEXOKINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672869};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001875};
KW   Glycolysis {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672870};
KW   Kinase {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672871,
KW   ECO:0000313|EMBL:EED48784.1};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672883};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001875};
KW   Transferase {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672884}.
FT   DOMAIN       27    221       Hexokinase_1. {ECO:0000259|Pfam:PF00349}.
FT   DOMAIN      227    466       Hexokinase_2. {ECO:0000259|Pfam:PF03727}.
SQ   SEQUENCE   490 AA;  54147 MW;  28B891A5E6E37FF1 CRC64;
     MVGIGPKRPP SRKGSMHELP QNLLEQIKQF EDIFTVDGAK LKQIADHFVK ELEKGLSVEG
     GNIPMNVTWV MGFPDGDEQG TFLALDMGGT NLRVCEITLT EEKGAFDITQ SKYRMPEELK
     TGTAEELWEY IADCLQQFIE SHHENEKLSK LPLGFTFSYP ATQEYIDHGV LQRWTKGFDI
     DGVEGQDVVP PLEAILKKRG LPIKVAALIN DTTGTLIASS YTDSDMKIGC IFGTGVNAAY
     MEHCGSVPKL AHKNLPPDMP VAINCEYGAF DNEHVVLPLT KYDIIIDRDS PRPGQQAFEK
     MTAGLYLGEI FRLALLDLLE TRPGLIFQGQ DTSQLRKPYL LDASFLAAIE DDPYENLQET
     QELMERKLNI KATQQELEMI RRLAELIGTR AARLSACGVA AICKKKNIES CHVGADGSVF
     TKYPHFKARG AQALREILDW APNEKDKVVI MAAEDGSGVG AALIAALTLK RVKAGISCGI
     RDMADMQSLI
//
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