ID B9KY20_THERP Unreviewed; 536 AA.
AC B9KY20;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 07-SEP-2016, entry version 44.
DE SubName: Full=Probable acetolactate synthase large subunit {ECO:0000313|EMBL:ACM04855.1};
DE EC=2.2.1.6 {ECO:0000313|EMBL:ACM04855.1};
GN OrderedLocusNames=trd_0363 {ECO:0000313|EMBL:ACM04855.1};
OS Thermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2).
OC Bacteria; Chloroflexi; Thermomicrobiales; Thermomicrobiaceae;
OC Thermomicrobium.
OX NCBI_TaxID=309801 {ECO:0000313|EMBL:ACM04855.1, ECO:0000313|Proteomes:UP000000447};
RN [1] {ECO:0000313|EMBL:ACM04855.1, ECO:0000313|Proteomes:UP000000447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27502 / DSM 5159 / P-2
RC {ECO:0000313|Proteomes:UP000000447};
RX PubMed=19148287; DOI=10.1371/journal.pone.0004207;
RA Wu D., Raymond J., Wu M., Chatterji S., Ren Q., Graham J.E.,
RA Bryant D.A., Robb F., Colman A., Tallon L.J., Badger J.H., Madupu R.,
RA Ward N.L., Eisen J.A.;
RT "Complete genome sequence of the aerobic CO-oxidizing thermophile
RT Thermomicrobium roseum.";
RL PLoS ONE 4:E4207-E4207(2009).
CC -!- SIMILARITY: Belongs to the TPP enzyme family.
CC {ECO:0000256|RuleBase:RU362132}.
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DR EMBL; CP001275; ACM04855.1; -; Genomic_DNA.
DR RefSeq; WP_012641770.1; NC_011959.1.
DR ProteinModelPortal; B9KY20; -.
DR STRING; 309801.trd_0363; -.
DR EnsemblBacteria; ACM04855; ACM04855; trd_0363.
DR KEGG; tro:trd_0363; -.
DR PATRIC; 23911946; VBITheRos91376_0357.
DR eggNOG; ENOG4105C7K; Bacteria.
DR eggNOG; COG0028; LUCA.
DR HOGENOM; HOG000258446; -.
DR KO; K01652; -.
DR OMA; MATCGEV; -.
DR OrthoDB; POG091H02KO; -.
DR BioCyc; TROS309801:GI0S-361-MONOMER; -.
DR Proteomes; UP000000447; Chromosome.
DR GO; GO:0003984; F:acetolactate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR Gene3D; 3.40.50.1220; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR012000; Thiamin_PyroP_enz_cen_dom.
DR InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom.
DR InterPro; IPR000399; TPP-bd_CS.
DR InterPro; IPR011766; TPP_enzyme-bd_C.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR Pfam; PF00205; TPP_enzyme_M; 1.
DR Pfam; PF02776; TPP_enzyme_N; 1.
DR SUPFAM; SSF52467; SSF52467; 1.
DR SUPFAM; SSF52518; SSF52518; 2.
DR PROSITE; PS00187; TPP_ENZYMES; 1.
PE 3: Inferred from homology;
KW Complete proteome {ECO:0000313|Proteomes:UP000000447};
KW Reference proteome {ECO:0000313|Proteomes:UP000000447};
KW Thiamine pyrophosphate {ECO:0000256|RuleBase:RU362132};
KW Transferase {ECO:0000313|EMBL:ACM04855.1}.
FT DOMAIN 4 169 TPP_enzyme_N. {ECO:0000259|Pfam:PF02776}.
FT DOMAIN 193 326 TPP_enzyme_M. {ECO:0000259|Pfam:PF00205}.
FT DOMAIN 384 528 TPP_enzyme_C. {ECO:0000259|Pfam:PF02775}.
SQ SEQUENCE 536 AA; 57601 MW; 187D1631B895EE47 CRC64;
MRVTGGEAVV RTLERLGVEV VFGIPGVHTL AIYDALYSSP IRHVLARHEQ GAGFMADGYA
RVSGKPGVAI VITGPGVTNI ATAIGEAYAD SSPVVVIASN VEQAWQGQML GHLHDCKDQL
GIMRVVTKWA DRARSVEDVP RLLRTAFAEA ISGRRRPTHL EVPLDVLHGS GDIELAHLAP
LSMERSQPRR SAIELAARMI EEAERVVLYC GGGVVASGAT AELSALAERL GAAVITSLQG
KGAIPEDHPR CLGNLWEPEN AVERVLRESD LVIVIGSKLG AQDTANGRLP LPDRRIRIDI
DAQEILRNYP PTLPIVADAR ETVRALLSEL TSRGITKQGW PVDVLQATKR EALATAWGAG
QAEWLRAIRA VLPRDGILVS DMTMMAYVGN RHYPVYEPGT YLFPTGYGTL GFALPAAIGA
KIARPEAAVV ALVGDGGYQF TMQELATAVQ FRIGIPIILF NDASYTAVKD EQARSFGGRF
IAVDLVNPDF QKLAAAYGIP SEYVTSPQTL EGAIARALER DLPTLIEVPI DFPLGA
//
