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Database: UniProt/TrEMBL
Entry: C4JJL5_UNCRE
LinkDB: C4JJL5_UNCRE
Original site: C4JJL5_UNCRE 
ID   C4JJL5_UNCRE            Unreviewed;       189 AA.
AC   C4JJL5;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   24-JUN-2015, entry version 29.
DE   RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2 {ECO:0000256|RuleBase:RU361136};
DE            Short=Oligosaccharyl transferase subunit OST2 {ECO:0000256|RuleBase:RU361136};
DE            EC=2.4.99.18 {ECO:0000256|RuleBase:RU361136};
GN   ORFNames=UREG_01822 {ECO:0000313|EMBL:EEP76973.1};
OS   Uncinocarpus reesii (strain UAMH 1704).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus.
OX   NCBI_TaxID=336963 {ECO:0000313|EMBL:EEP76973.1, ECO:0000313|Proteomes:UP000002058};
RN   [1] {ECO:0000313|Proteomes:UP000002058}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 1704 {ECO:0000313|Proteomes:UP000002058};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J.,
RA   Wortman J.R., Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E.,
RA   Zeng Q., Hung C.-Y., McMahan C., Muszewska A., Grynberg M.,
RA   Mandel M.A., Kellner E.M., Barker B.M., Galgiani J.N., Orbach M.J.,
RA   Kirkland T.N., Cole G.T., Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens
RT   Coccidioides and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- FUNCTION: Essential subunit of the N-oligosaccharyl transferase
CC       (OST) complex which catalyzes the transfer of a high mannose
CC       oligosaccharide from a lipid-linked oligosaccharide donor to an
CC       asparagine residue within an Asn-X-Ser/Thr consensus motif in
CC       nascent polypeptide chains. {ECO:0000256|RuleBase:RU361136}.
CC   -!- CATALYTIC ACTIVITY: Dolichyl diphosphooligosaccharide + [protein]-
CC       L-asparagine = dolichyl diphosphate + a glycoprotein with the
CC       oligosaccharide chain attached by N-beta-D-glycosyl linkage to a
CC       protein L-asparagine. {ECO:0000256|RuleBase:RU361136}.
CC   -!- PATHWAY: Protein modification; protein glycosylation.
CC       {ECO:0000256|RuleBase:RU361136}.
CC   -!- SUBUNIT: Component of the oligosaccharyltransferase (OST) complex.
CC       {ECO:0000256|RuleBase:RU361136}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|RuleBase:RU361136}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU361136}.
CC   -!- SIMILARITY: Belongs to the DAD/OST2 family.
CC       {ECO:0000256|RuleBase:RU361136}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU361136}.
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DR   EMBL; CH476615; EEP76973.1; -; Genomic_DNA.
DR   RefSeq; XP_002542306.1; XM_002542260.1.
DR   STRING; 336963.XP_002542306.1; -.
DR   GeneID; 8438459; -.
DR   KEGG; ure:UREG_01822; -.
DR   InParanoid; C4JJL5; -.
DR   KO; K12668; -.
DR   OrthoDB; EOG757D9B; -.
DR   UniPathway; UPA00378; -.
DR   Proteomes; UP000002058; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008250; C:oligosaccharyltransferase complex; IEA:InterPro.
DR   GO; GO:0004579; F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR003038; DAD/Ost2.
DR   PANTHER; PTHR10705; PTHR10705; 1.
DR   Pfam; PF02109; DAD; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002058};
KW   Endoplasmic reticulum {ECO:0000256|RuleBase:RU361136};
KW   Membrane {ECO:0000256|RuleBase:RU361136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002058};
KW   Transferase {ECO:0000256|RuleBase:RU361136};
KW   Transmembrane {ECO:0000256|RuleBase:RU361136};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361136}.
FT   TRANSMEM    109    129       Helical. {ECO:0000256|RuleBase:RU361136}.
FT   TRANSMEM    135    153       Helical. {ECO:0000256|RuleBase:RU361136}.
SQ   SEQUENCE   189 AA;  20061 MW;  F663D31F72F0B5F5 CRC64;
     MEGIEPVRAY PINPPREPAL SFTHGLLLIL LGIKDLPAMA PKRPANGSAT VSSSSSSSKP
     TTTSVPPSTT AKPSGPIAFT AKSPPQEIIL GVWQRYLVQT SQRTKLLDAF MAFLVLVGAV
     QFAYCVLAGN YPFNAFLSGF CAAVGQFVLT ASLRMQTSDQ DVKSISRSKS STPAVTKAEA
     SSDRVSPER
//
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