GenomeNet

Database: UniProt/TrEMBL
Entry: C4JJL5_UNCRE
LinkDB: C4JJL5_UNCRE
Original site: C4JJL5_UNCRE 
ID   C4JJL5_UNCRE            Unreviewed;       189 AA.
AC   C4JJL5;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   29-OCT-2014, entry version 24.
DE   RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2 {ECO:0000256|RuleBase:RU361136};
DE            Short=Oligosaccharyl transferase subunit OST2 {ECO:0000256|RuleBase:RU361136};
DE            EC=2.4.99.18 {ECO:0000256|RuleBase:RU361136};
GN   ORFNames=UREG_01822 {ECO:0000313|EMBL:EEP76973.1};
OS   Uncinocarpus reesii (strain UAMH 1704).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus.
OX   NCBI_TaxID=336963 {ECO:0000313|EMBL:EEP76973.1, ECO:0000313|Proteomes:UP000002058};
RN   [1] {ECO:0000313|Proteomes:UP000002058}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 1704 {ECO:0000313|Proteomes:UP000002058};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J.,
RA   Wortman J.R., Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E.,
RA   Zeng Q., Hung C.Y., McMahan C., Muszewska A., Grynberg M.,
RA   Mandel M.A., Kellner E.M., Barker B.M., Galgiani J.N., Orbach M.J.,
RA   Kirkland T.N., Cole G.T., Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens
RT   Coccidioides and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- FUNCTION: Essential subunit of the N-oligosaccharyl transferase
CC       (OST) complex which catalyzes the transfer of a high mannose
CC       oligosaccharide from a lipid-linked oligosaccharide donor to an
CC       asparagine residue within an Asn-X-Ser/Thr consensus motif in
CC       nascent polypeptide chains. {ECO:0000256|RuleBase:RU361136}.
CC   -!- CATALYTIC ACTIVITY: Dolichyl diphosphooligosaccharide + [protein]-
CC       L-asparagine = dolichyl diphosphate + a glycoprotein with the
CC       oligosaccharide chain attached by N-beta-D-glycosyl linkage to a
CC       protein L-asparagine. {ECO:0000256|RuleBase:RU361136}.
CC   -!- PATHWAY: Protein modification; protein glycosylation.
CC       {ECO:0000256|RuleBase:RU361136}.
CC   -!- SUBUNIT: Component of the oligosaccharyltransferase (OST) complex.
CC       {ECO:0000256|RuleBase:RU361136}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|RuleBase:RU361136}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU361136}.
CC   -!- SIMILARITY: Belongs to the DAD/OST2 family.
CC       {ECO:0000256|RuleBase:RU361136}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU361136}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CH476615; EEP76973.1; -; Genomic_DNA.
DR   RefSeq; XP_002542306.1; XM_002542260.1.
DR   GeneID; 8438459; -.
DR   KEGG; ure:UREG_01822; -.
DR   InParanoid; C4JJL5; -.
DR   KO; K12668; -.
DR   OrthoDB; EOG757D9B; -.
DR   UniPathway; UPA00378; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008250; C:oligosaccharyltransferase complex; IEA:InterPro.
DR   GO; GO:0004579; F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR003038; DAD/Ost2.
DR   PANTHER; PTHR10705; PTHR10705; 1.
DR   Pfam; PF02109; DAD; 1.
DR   PIRSF; PIRSF005588; DAD; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002058};
KW   Endoplasmic reticulum {ECO:0000256|RuleBase:RU361136};
KW   Membrane {ECO:0000256|RuleBase:RU361136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002058};
KW   Transferase {ECO:0000256|RuleBase:RU361136};
KW   Transmembrane {ECO:0000256|RuleBase:RU361136};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361136}.
SQ   SEQUENCE   189 AA;  20061 MW;  F663D31F72F0B5F5 CRC64;
     MEGIEPVRAY PINPPREPAL SFTHGLLLIL LGIKDLPAMA PKRPANGSAT VSSSSSSSKP
     TTTSVPPSTT AKPSGPIAFT AKSPPQEIIL GVWQRYLVQT SQRTKLLDAF MAFLVLVGAV
     QFAYCVLAGN YPFNAFLSGF CAAVGQFVLT ASLRMQTSDQ DVKSISRSKS STPAVTKAEA
     SSDRVSPER
//
DBGET integrated database retrieval system