ID C4XAE1_KLEPN Unreviewed; 488 AA.
AC C4XAE1;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 03-APR-2013, entry version 29.
DE RecName: Full=Pyruvate kinase;
DE EC=2.7.1.40;
GN Name=pykA; ORFNames=KP1_3499;
OS Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC Enterobacteriaceae; Klebsiella.
OX NCBI_TaxID=484021;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NTUH-K2044;
RA Wu K.M., Tsai S.F.;
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NTUH-K2044;
RX PubMed=19447910; DOI=10.1128/JB.00315-09;
RA Wu K.-M., Li L.-H., Yan J.-J., Tsao N., Liao T.-L., Tsai H.-C.,
RA Fung C.-P., Chen H.-J., Liu Y.-M., Wang J.-T., Fang C.-T.,
RA Chang S.-C., Shu H.-Y., Liu T.-T., Chen Y.-T., Shiau Y.-R.,
RA Lauderdale T.-L., Su I.-J., Kirby R., Tsai S.-F.;
RT "Genome sequencing and comparative analysis of Klebsiella pneumoniae
RT NTUH-K2044, a strain causing liver abscess and meningitis.";
RL J. Bacteriol. 191:4492-4501(2009).
CC -!- CATALYTIC ACTIVITY: ATP + pyruvate = ADP + phosphoenolpyruvate.
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-
CC glyceraldehyde 3-phosphate: step 5/5.
CC -!- SIMILARITY: Belongs to the pyruvate kinase family.
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DR EMBL; AP006725; BAH64099.1; -; Genomic_DNA.
DR RefSeq; YP_002920166.1; NC_012731.1.
DR ProteinModelPortal; C4XAE1; -.
DR STRING; 484021.KP1_3499; -.
DR EnsemblBacteria; BAH64099; BAH64099; KP1_3499.
DR GeneID; 7949178; -.
DR KEGG; kpu:KP1_3499; -.
DR PATRIC; 20450513; VBIKlePne21779_3064.
DR eggNOG; COG0469; -.
DR KO; K00873; -.
DR ProtClustDB; PRK05826; -.
DR UniPathway; UPA00109; UER00188.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0030955; F:potassium ion binding; IEA:InterPro.
DR GO; GO:0004743; F:pyruvate kinase activity; IEA:EC.
DR GO; GO:0006096; P:glycolysis; IEA:UniProtKB-UniPathway.
DR Gene3D; 2.40.33.10; -; 1.
DR Gene3D; 3.20.20.60; -; 2.
DR Gene3D; 3.40.1380.20; -; 1.
DR InterPro; IPR001697; Pyr_Knase.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase.
DR InterPro; IPR011037; Pyrv_Knase-like_insert_dom.
DR InterPro; IPR015794; Pyrv_Knase_a/b.
DR InterPro; IPR018209; Pyrv_Knase_AS.
DR InterPro; IPR015793; Pyrv_Knase_brl.
DR InterPro; IPR015795; Pyrv_Knase_C.
DR InterPro; IPR015806; Pyrv_Knase_insert_dom.
DR PANTHER; PTHR11817; PTHR11817; 1.
DR Pfam; PF00224; PK; 1.
DR Pfam; PF02887; PK_C; 1.
DR PRINTS; PR01050; PYRUVTKNASE.
DR SUPFAM; SSF50800; PK_B_barrel_like; 1.
DR SUPFAM; SSF52935; Pyruvate_kinase; 1.
DR SUPFAM; SSF51621; Pyrv/PenolPyrv_Kinase_cat; 1.
DR TIGRFAMs; TIGR01064; pyruv_kin; 1.
DR PROSITE; PS00110; PYRUVATE_KINASE; 1.
PE 3: Inferred from homology;
KW Glycolysis; Kinase; Magnesium; Pyruvate; Transferase.
SQ SEQUENCE 488 AA; 52488 MW; B95CC38B8420E414 CRC64;
MYQSTEYYMS RRLRRTKIVT TLGPATDRDN NLEKVIAAGA NVVRMNFSHG TPEDHQLRAD
KVREIAAKLG RHVAILGDLQ GPKIRVSTFK EGKIFLNVGD KFLLDANLGK GEGDKEKVGI
DYKGLPADVV PGDILLLDDG RVQLKVLEVQ GMKVFTEVTV GGPLSNNKGI NKLGGGLSAE
ALTDKDKADI VTAAKIGVDY LAVSFPRCGE DLNYARRLAR DAGCDAKIVA KVERAEAVCD
QDAMDDVILA SDVVMVARGD LGVEIGDPEL VGIQKALIRR ARQLNRSVIT ATQMMESMIT
NPMPTRAEVM DVANAVLDGT DAVMLSAETA AGQYPSETVA AMARVCLGAE KIPSLNVSKH
RLDVQFDNVE EAIAMSAMYA ANHLKGITAI ITMTESGRTA LMTSRISSGL PIFALSRHER
TLNLTALYRG VTPVFFDSQN DGVAAAHDAV NLLRDKGYLV SGDLVVVTQG DVMSTIGSTN
TTRILTVE
//
