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Database: UniProt/TrEMBL
Entry: C4XAE1_KLEPN
LinkDB: C4XAE1_KLEPN
Original site: C4XAE1_KLEPN 
ID   C4XAE1_KLEPN            Unreviewed;       488 AA.
AC   C4XAE1;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   13-NOV-2013, entry version 32.
DE   RecName: Full=Pyruvate kinase;
DE            EC=2.7.1.40;
GN   Name=pykA; ORFNames=KP1_3499;
OS   Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Klebsiella.
OX   NCBI_TaxID=484021;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NTUH-K2044;
RA   Wu K.M., Tsai S.F.;
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NTUH-K2044;
RX   PubMed=19447910; DOI=10.1128/JB.00315-09;
RA   Wu K.-M., Li L.-H., Yan J.-J., Tsao N., Liao T.-L., Tsai H.-C.,
RA   Fung C.-P., Chen H.-J., Liu Y.-M., Wang J.-T., Fang C.-T.,
RA   Chang S.-C., Shu H.-Y., Liu T.-T., Chen Y.-T., Shiau Y.-R.,
RA   Lauderdale T.-L., Su I.-J., Kirby R., Tsai S.-F.;
RT   "Genome sequencing and comparative analysis of Klebsiella pneumoniae
RT   NTUH-K2044, a strain causing liver abscess and meningitis.";
RL   J. Bacteriol. 191:4492-4501(2009).
CC   -!- CATALYTIC ACTIVITY: ATP + pyruvate = ADP + phosphoenolpyruvate.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-
CC       glyceraldehyde 3-phosphate: step 5/5.
CC   -!- SIMILARITY: Belongs to the pyruvate kinase family.
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DR   EMBL; AP006725; BAH64099.1; -; Genomic_DNA.
DR   RefSeq; YP_002920166.1; NC_012731.1.
DR   ProteinModelPortal; C4XAE1; -.
DR   STRING; 484021.KP1_3499; -.
DR   EnsemblBacteria; BAH64099; BAH64099; KP1_3499.
DR   GeneID; 7949178; -.
DR   KEGG; kpu:KP1_3499; -.
DR   PATRIC; 20450513; VBIKlePne21779_3064.
DR   eggNOG; COG0469; -.
DR   KO; K00873; -.
DR   OrthoDB; EOG6GBMB0; -.
DR   ProtClustDB; PRK05826; -.
DR   BioCyc; KPNE484021:GCWL-3252-MONOMER; -.
DR   UniPathway; UPA00109; UER00188.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030955; F:potassium ion binding; IEA:InterPro.
DR   GO; GO:0004743; F:pyruvate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006096; P:glycolysis; IEA:UniProtKB-UniPathway.
DR   Gene3D; 2.40.33.10; -; 1.
DR   Gene3D; 3.20.20.60; -; 2.
DR   Gene3D; 3.40.1380.20; -; 1.
DR   InterPro; IPR001697; Pyr_Knase.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   InterPro; IPR011037; Pyrv_Knase-like_insert_dom.
DR   InterPro; IPR015794; Pyrv_Knase_a/b.
DR   InterPro; IPR018209; Pyrv_Knase_AS.
DR   InterPro; IPR015793; Pyrv_Knase_brl.
DR   InterPro; IPR015795; Pyrv_Knase_C.
DR   InterPro; IPR015806; Pyrv_Knase_insert_dom.
DR   PANTHER; PTHR11817; PTHR11817; 1.
DR   Pfam; PF00224; PK; 1.
DR   Pfam; PF02887; PK_C; 1.
DR   PRINTS; PR01050; PYRUVTKNASE.
DR   SUPFAM; SSF50800; SSF50800; 1.
DR   SUPFAM; SSF51621; SSF51621; 2.
DR   SUPFAM; SSF52935; SSF52935; 1.
DR   TIGRFAMs; TIGR01064; pyruv_kin; 1.
DR   PROSITE; PS00110; PYRUVATE_KINASE; 1.
PE   3: Inferred from homology;
KW   Glycolysis; Kinase; Magnesium; Pyruvate; Transferase.
SQ   SEQUENCE   488 AA;  52488 MW;  B95CC38B8420E414 CRC64;
     MYQSTEYYMS RRLRRTKIVT TLGPATDRDN NLEKVIAAGA NVVRMNFSHG TPEDHQLRAD
     KVREIAAKLG RHVAILGDLQ GPKIRVSTFK EGKIFLNVGD KFLLDANLGK GEGDKEKVGI
     DYKGLPADVV PGDILLLDDG RVQLKVLEVQ GMKVFTEVTV GGPLSNNKGI NKLGGGLSAE
     ALTDKDKADI VTAAKIGVDY LAVSFPRCGE DLNYARRLAR DAGCDAKIVA KVERAEAVCD
     QDAMDDVILA SDVVMVARGD LGVEIGDPEL VGIQKALIRR ARQLNRSVIT ATQMMESMIT
     NPMPTRAEVM DVANAVLDGT DAVMLSAETA AGQYPSETVA AMARVCLGAE KIPSLNVSKH
     RLDVQFDNVE EAIAMSAMYA ANHLKGITAI ITMTESGRTA LMTSRISSGL PIFALSRHER
     TLNLTALYRG VTPVFFDSQN DGVAAAHDAV NLLRDKGYLV SGDLVVVTQG DVMSTIGSTN
     TTRILTVE
//
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