ID C5AIT1_BURGB Unreviewed; 346 AA.
AC C5AIT1;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:ACR31811.1};
GN OrderedLocusNames=bglu_2g14520 {ECO:0000313|EMBL:ACR31811.1};
OS Burkholderia glumae (strain BGR1).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=626418 {ECO:0000313|EMBL:ACR31811.1, ECO:0000313|Proteomes:UP000002187};
RN [1] {ECO:0000313|EMBL:ACR31811.1, ECO:0000313|Proteomes:UP000002187}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGR1 {ECO:0000313|EMBL:ACR31811.1,
RC ECO:0000313|Proteomes:UP000002187};
RX PubMed=19329631; DOI=10.1128/JB.00349-09;
RA Lim J., Lee T.H., Nahm B.H., Choi Y.D., Kim M., Hwang I.;
RT "Complete genome sequence of Burkholderia glumae BGR1.";
RL J. Bacteriol. 191:3758-3759(2009).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
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DR EMBL; CP001504; ACR31811.1; -; Genomic_DNA.
DR RefSeq; WP_015877504.1; NC_012721.2.
DR AlphaFoldDB; C5AIT1; -.
DR STRING; 626418.bglu_2g14520; -.
DR GeneID; 58139240; -.
DR KEGG; bgl:bglu_2g14520; -.
DR PATRIC; fig|626418.3.peg.1738; -.
DR eggNOG; COG1064; Bacteria.
DR HOGENOM; CLU_026673_11_2_4; -.
DR Proteomes; UP000002187; Chromosome 2.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR CDD; cd08260; Zn_ADH6; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43401:SF5; ALCOHOL DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR43401; L-THREONINE 3-DEHYDROGENASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000002187};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 10..343
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 346 AA; 36719 MW; 9C69DA58E848FC07 CRC64;
MKAVMFESFG ERPKLVSLRD PSPETHGVVI KVQATGVCRS DWHGWVGHDT DIELPHVPGH
ELAGTIEAVG KDVSQWQVGD RVTVPFVGGC GSCPECHAGH QQVCHSQFQP GFTHWGSFAE
YVSIHRADLN LVALPESITF ATAASLGCRF VTSFRAVVDQ GKVTAGQWVA VHGCGGVGLS
AIMIANALGA NVVAVDIAED KLALAKRLGA AATIDAKSVA DVPEAVMEVT GGGAHVSLDA
LGSPVTCFNS IQNLRRRGKH VQVGLMLGEH STPSVPMSKI VGWELEVLGS HGMQAHRYDA
MMPMILAGKL KPELLVGKEI SLEESIDALM SMDKFQGTGT TVVTRF
//
