GenomeNet

Database: UniProt/TrEMBL
Entry: C5M2X5_CANTT
LinkDB: C5M2X5_CANTT
Original site: C5M2X5_CANTT 
ID   C5M2X5_CANTT            Unreviewed;       483 AA.
AC   C5M2X5;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   07-JUN-2017, entry version 39.
DE   RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE            EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN   ORFNames=CTRG_00414 {ECO:0000313|EMBL:EER35675.1};
OS   Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Debaryomycetaceae;
OC   Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294747 {ECO:0000313|EMBL:EER35675.1, ECO:0000313|Proteomes:UP000002037};
RN   [1] {ECO:0000313|EMBL:EER35675.1, ECO:0000313|Proteomes:UP000002037}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L.,
RA   Agrafioti I., Arnaud M.B., Bates S., Brown A.J., Brunke S.,
RA   Costanzo M.C., Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L.,
RA   Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R.,
RA   Neiman A.M., Nikolaou E., Quail M.A., Quinn J., Santos M.C.,
RA   Schmitzberger F.F., Sherlock G., Shah P., Silverstein K.A.,
RA   Skrzypek M.S., Soll D., Staggs R., Stansfield I., Stumpf M.P.,
RA   Sudbery P.E., Srikantha T., Zeng Q., Berman J., Berriman M.,
RA   Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- SIMILARITY: Belongs to the hexokinase family.
CC       {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672880}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; GG692395; EER35675.1; -; Genomic_DNA.
DR   RefSeq; XP_002545633.1; XM_002545587.1.
DR   STRING; 294747.XP_002545633.1; -.
DR   EnsemblFungi; EER35675; EER35675; CTRG_00414.
DR   GeneID; 8296095; -.
DR   KEGG; ctp:CTRG_00414; -.
DR   eggNOG; KOG1369; Eukaryota.
DR   eggNOG; COG5026; LUCA.
DR   KO; K00844; -.
DR   OrthoDB; EOG092C2JW4; -.
DR   Proteomes; UP000002037; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR   GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001678; P:cellular glucose homeostasis; IEA:InterPro.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   InterPro; IPR001312; Hexokinase.
DR   InterPro; IPR022673; Hexokinase_C.
DR   InterPro; IPR022672; Hexokinase_N.
DR   PANTHER; PTHR19443; PTHR19443; 1.
DR   Pfam; PF00349; Hexokinase_1; 1.
DR   Pfam; PF03727; Hexokinase_2; 1.
DR   PROSITE; PS51748; HEXOKINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672869};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002037};
KW   Glycolysis {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672870};
KW   Kinase {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672871,
KW   ECO:0000313|EMBL:EER35675.1};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672883};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002037};
KW   Transferase {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672884}.
FT   DOMAIN       27    220       Hexokinase_1. {ECO:0000259|Pfam:PF00349}.
FT   DOMAIN      226    467       Hexokinase_2. {ECO:0000259|Pfam:PF03727}.
SQ   SEQUENCE   483 AA;  53206 MW;  1E4BCEDDA30C0130 CRC64;
     MVHLGPKPAQ PRKGTFTDVP SQLLEAIKPF EKEFTISGET LRAIVAHFIK ELNRGLSKQG
     GNIPMIPGWV MEYPTGKETG NYLAIDLGGT NLRVVLVKLG GNRDFDTTQS KFALPSHMRT
     ATKDELWDFI AKCLKQVVDE VFPEGVTQPI PLGFTFSYPA SQDRINEGVL QRWTKGWAID
     GIEGHDVVPM LQSAVKKVGV PINVVALIND TTGTLVASLY TDPETKMGVI FGTGVNGAYY
     DVVGEIPKLE GRCGADIPPT SLMAINCEYG SFDNEHFILP RTKYDIQIDA ESPKPGQQTF
     EKMNSGYYLG ELLRLILLEL ADEKKLIFKG QNIDKLRKPY VMDTSFPSRI ELDPFENLSD
     VADIFQDELG IQTTEPERKI IRRLSELIGE RSARLSVCGI AAICQKRGYE TAHIAADGSV
     FNRYPGFKER AAKALRDIYQ WPATQKDPIV IVAAEDGSGV GAAIIAALTE KRLKEGKSVG
     VIA
//
DBGET integrated database retrieval system