ID   C5WSM8_SORBI            Unreviewed;       711 AA.
AC   C5WSM8;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   RecName: Full=Vacuolar protein 14 C-terminal Fig4-binding domain-containing protein {ECO:0000259|Pfam:PF11916};
GN   ORFNames=SORBI_3001G451400 {ECO:0000313|EMBL:EER92621.1};
OS   Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX   NCBI_TaxID=4558 {ECO:0000313|EMBL:EER92621.1, ECO:0000313|Proteomes:UP000000768};
RN   [1] {ECO:0000313|EMBL:EER92621.1, ECO:0000313|Proteomes:UP000000768}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX   PubMed=19189423; DOI=10.1038/nature07723;
RA   Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA   Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA   Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA   Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA   Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA   Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA   Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA   Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT   "The Sorghum bicolor genome and the diversification of grasses.";
RL   Nature 457:551-556(2009).
RN   [2] {ECO:0000313|Proteomes:UP000000768}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX   PubMed=29161754; DOI=10.1111/tpj.13781;
RA   McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA   Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA   Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT   "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT   a transcriptome atlas, and signatures of genome organization.";
RL   Plant J. 93:338-354(2018).
CC   -!- SIMILARITY: Belongs to the VAC14 family.
CC       {ECO:0000256|ARBA:ARBA00010225}.
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DR   EMBL; CM000760; EER92621.1; -; Genomic_DNA.
DR   RefSeq; XP_002465623.1; XM_002465578.1.
DR   AlphaFoldDB; C5WSM8; -.
DR   STRING; 4558.C5WSM8; -.
DR   EnsemblPlants; EER92621; EER92621; SORBI_3001G451400.
DR   GeneID; 8085276; -.
DR   Gramene; EER92621; EER92621; SORBI_3001G451400.
DR   KEGG; sbi:8085276; -.
DR   eggNOG; KOG0212; Eukaryota.
DR   HOGENOM; CLU_007740_1_0_1; -.
DR   InParanoid; C5WSM8; -.
DR   OMA; CYQHVSE; -.
DR   OrthoDB; 5481081at2759; -.
DR   Proteomes; UP000000768; Chromosome 1.
DR   GO; GO:0010008; C:endosome membrane; IBA:GO_Central.
DR   GO; GO:0070772; C:PAS complex; IBA:GO_Central.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR026825; Vac14.
DR   InterPro; IPR021841; VAC14_Fig4p-bd.
DR   PANTHER; PTHR16023:SF0; PROTEIN VAC14 HOMOLOG; 1.
DR   PANTHER; PTHR16023; TAX1 BINDING PROTEIN-RELATED; 1.
DR   Pfam; PF12755; Vac14_Fab1_bd; 1.
DR   Pfam; PF11916; Vac14_Fig4_bd; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50077; HEAT_REPEAT; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          93..128
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT   DOMAIN          431..609
FT                   /note="Vacuolar protein 14 C-terminal Fig4-binding"
FT                   /evidence="ECO:0000259|Pfam:PF11916"
FT   REGION          691..711
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   711 AA;  80443 MW;  68085BA8F1A8BB5D CRC64;
     MAQEALSVIP SAVLRNLSDK LYEKRKNAAL EIEGIVKQLA TAGEHEKISA VILLLTHDYT
     YSPQANHRKG GLIGLAAVTV GLTSEAAQHL EQIVPPVLNS FLDQDSRVRY YACEALYNIA
     KVVRGDFIIY FNKIFDALCK LSADSDANVQ SAAHLLDRLV KDIVTESDQF SIEEFIPLLR
     ERMNVLNPYV RQFLVGWITV LDSVPDIDML GFLPDFLDGL FNMLSDSSHE IRQQADAALS
     EFLQEIKNSP NVDYGRMAEI LVRRAGSTDE FTRLTSITWI NEFVKLGGEQ LVPYYADILG
     AILPCISDEE EKIRVVARET NEELRAIKAD PAEGFDIGAI LSIAKRELNS EHEATRIEAL
     HWFFTLLDRY RSEFLAYLND IFDPLLNALS DPSDAVVLLV LEVHARIAEE SHHFHHLVSY
     LIRTFHNNHF LLEKRGALIV RRLCVLLGAE KVYREFSTIL ESEANLDFAS VMVQALNLIL
     LTSTELGELR SVLKKSLVDS CGKDLFQSLY ASWRHSPMAT ISLCLLAQAY SHASCVIQSL
     GEEDINVKFL VQLDKLIRLL ETPVFAYLRL QLLEPGKHTW LLKTLYGLLM LLPQQSAAFK
     ILRTRLKTVP FSENLKRTSS ANPYSQILQV TEDGNRNQDT QNYSAINFPF LLQQFENMQL
     QHRNHLKDQL QSRKSASALT LSQEIQRYEE AHSSSLSEIN RPPSRTSKGI L
//