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Database: UniProt/TrEMBL
Entry: C5XJZ6_SORBI
LinkDB: C5XJZ6_SORBI
Original site: C5XJZ6_SORBI 
ID   C5XJZ6_SORBI            Unreviewed;       506 AA.
AC   C5XJZ6;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   07-JUN-2017, entry version 65.
DE   RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE            EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN   ORFNames=SORBI_3003G291800 {ECO:0000313|EMBL:EES03587.1};
OS   Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae;
OC   PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Sorghinae;
OC   Sorghum.
OX   NCBI_TaxID=4558 {ECO:0000313|EMBL:EES03587.1, ECO:0000313|Proteomes:UP000000768};
RN   [1] {ECO:0000313|EMBL:EES03587.1, ECO:0000313|Proteomes:UP000000768}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX   PubMed=19189423; DOI=10.1038/nature07723;
RA   Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA   Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A.,
RA   Schmutz J., Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K.,
RA   Chapman J., Feltus F.A., Gowik U., Grigoriev I.V., Lyons E.,
RA   Maher C.A., Martis M., Narechania A., Otillar R.P., Penning B.W.,
RA   Salamov A.A., Wang Y., Zhang L., Carpita N.C., Freeling M.,
RA   Gingle A.R., Hash C.T., Keller B., Klein P., Kresovich S.,
RA   McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman, Ware D.,
RA   Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT   "The Sorghum bicolor genome and the diversification of grasses.";
RL   Nature 457:551-556(2009).
CC   -!- SIMILARITY: Belongs to the hexokinase family.
CC       {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672880}.
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DR   EMBL; CM000762; EES03587.1; -; Genomic_DNA.
DR   RefSeq; XP_002458467.1; XM_002458422.1.
DR   UniGene; Sbi.16662; -.
DR   STRING; 4558.Sb03g034230.1; -.
DR   EnsemblPlants; EES03587; EES03587; SORBI_003G291800.
DR   GeneID; 8062170; -.
DR   Gramene; EES03587; EES03587; SORBI_003G291800.
DR   KEGG; sbi:SORBI_03g034230; -.
DR   eggNOG; KOG1369; Eukaryota.
DR   eggNOG; COG5026; LUCA.
DR   HOGENOM; HOG000162670; -.
DR   InParanoid; C5XJZ6; -.
DR   KO; K00844; -.
DR   OMA; QEVKRYY; -.
DR   OrthoDB; EOG093608SG; -.
DR   Proteomes; UP000000768; Chromosome 3.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005739; C:mitochondrion; IEA:EnsemblPlants.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008865; F:fructokinase activity; IBA:GO_Central.
DR   GO; GO:0004340; F:glucokinase activity; IBA:GO_Central.
DR   GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR   GO; GO:0019158; F:mannokinase activity; IBA:GO_Central.
DR   GO; GO:0001678; P:cellular glucose homeostasis; IBA:GO_Central.
DR   GO; GO:0006096; P:glycolytic process; IBA:GO_Central.
DR   GO; GO:0009749; P:response to glucose; IEA:EnsemblPlants.
DR   InterPro; IPR001312; Hexokinase.
DR   InterPro; IPR019807; Hexokinase_BS.
DR   InterPro; IPR022673; Hexokinase_C.
DR   InterPro; IPR022672; Hexokinase_N.
DR   PANTHER; PTHR19443; PTHR19443; 1.
DR   Pfam; PF00349; Hexokinase_1; 1.
DR   Pfam; PF03727; Hexokinase_2; 1.
DR   PROSITE; PS00378; HEXOKINASE_1; 1.
DR   PROSITE; PS51748; HEXOKINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672869};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000768};
KW   Glycolysis {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672870};
KW   Kinase {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672871};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672883};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW   Transferase {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672884};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM      6     28       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       50    249       Hexokinase_1. {ECO:0000259|Pfam:PF00349}.
FT   DOMAIN      257    497       Hexokinase_2. {ECO:0000259|Pfam:PF03727}.
SQ   SEQUENCE   506 AA;  55066 MW;  18A135781FDC4F39 CRC64;
     MGKGAVVGTA VVVGAAAAAA VGVAVVSLSR RRRRRREAED ERKRKAAAVI EEVEQRFSTP
     TALLRGIADA MVEEMERGLR AEPHAPLKML ISYVDNLPTG DEQGLFYALD LGGTNFRVIR
     VQLGGRDKRV VKQQYEEVSI PPHLMVGTST ELFDFIAAEL EKFVRTEGED FHLPNGKQRE
     LGFTFSFPVH QTSISSGTLI KWTKGFSING TVGEDVVAEL SRAMERQGLD MKVAALVNDT
     VGTLAGGRYA DNDVVTAVIL GTGTNAAYVE HANAIPKWTG LLPRSGNMVI NMEWGNFRSD
     KLPMSEYDKS LDFESLNPGE QIYEKMISGM YLGEIVRRIL LKLAHDASLF GDVVPPKLEQ
     LFILRTPDMS AMHHDTSHDL KHLGAKLKDI LGVPDTSLEA RYITLHVCDL VAERGARLAA
     AGIYGILKKL GKDKLLSDFS QQRTVVAIDG GLYEHYKKFS ACLEATLTDL LGEEVASSVV
     VKLANDGSGI GAALLAASHS QYAEVA
//
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