ID C6AM43_AGGAN Unreviewed; 175 AA.
AC C6AM43;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 01-MAY-2013, entry version 23.
DE RecName: Full=Lysozyme;
DE EC=3.2.1.17;
GN OrderedLocusNames=NT05HA_0490;
OS Aggregatibacter aphrophilus (strain NJ8700) (Haemophilus aphrophilus).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Aggregatibacter.
OX NCBI_TaxID=634176;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJ8700;
RX PubMed=19447908; DOI=10.1128/JB.00447-09;
RA Di Bonaventura M.P., DeSalle R., Pop M., Nagarajan N., Figurski D.H.,
RA Fine D.H., Kaplan J.B., Planet P.J.;
RT "Complete genome sequence of Aggregatibacter (Haemophilus) aphrophilus
RT NJ8700.";
RL J. Bacteriol. 191:4693-4694(2009).
CC -!- CATALYTIC ACTIVITY: Hydrolysis of (1->4)-beta-linkages between N-
CC acetylmuramic acid and N-acetyl-D-glucosamine residues in a
CC peptidoglycan and between N-acetyl-D-glucosamine residues in
CC chitodextrins.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 24 family.
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DR EMBL; CP001607; ACS96905.1; -; Genomic_DNA.
DR RefSeq; YP_003006992.1; NC_012913.1.
DR STRING; 634176.NT05HA_0490; -.
DR EnsemblBacteria; ACS96905; ACS96905; NT05HA_0490.
DR GeneID; 8121925; -.
DR KEGG; aap:NT05HA_0490; -.
DR PATRIC; 31916079; VBIAggAph86045_0461.
DR HOGENOM; HOG000277068; -.
DR KO; K01185; -.
DR OMA; QSAFEAM; -.
DR BioCyc; AAPH634176:GHVL-480-MONOMER; -.
DR GO; GO:0003796; F:lysozyme activity; IEA:EC.
DR GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
DR GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR Gene3D; 1.10.530.40; -; 1.
DR InterPro; IPR002196; Glyco_hydro_24.
DR InterPro; IPR023346; Lysozyme-like_dom.
DR InterPro; IPR023347; Lysozyme_dom.
DR Pfam; PF00959; Phage_lysozyme; 1.
DR SUPFAM; SSF53955; SSF53955; 1.
PE 3: Inferred from homology;
KW Antimicrobial; Bacteriolytic enzyme; Complete proteome; Glycosidase;
KW Hydrolase.
SQ SEQUENCE 175 AA; 19427 MW; 340322F2746C3880 CRC64;
MLAKCSVVVI AGIILANYPD EIRTGEVGLL VIGNAEDCYR EPYKCPADVW TDGIGNTNDV
VLGRKLSDEE IAERWKDNIK IAENCVNRWA NGKELSQGAF EAAVSITFNV GCSKLKQATL
FKYARVGDIN LMCNQFPRWV YSQGKVLPGL VKRRNVEKAL CLGLIKSPEQ LSAYR
//
