GenomeNet

Database: UniProt/TrEMBL
Entry: C6DN43_MYCTK
LinkDB: C6DN43_MYCTK
Original site: C6DN43_MYCTK 
ID   C6DN43_MYCTK            Unreviewed;       738 AA.
AC   C6DN43;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   29-OCT-2014, entry version 36.
DE   SubName: Full=Glutamine-dependent NAD(+) synthetase nadE {ECO:0000313|EMBL:ACT24588.1};
GN   OrderedLocusNames=TBMG_01534 {ECO:0000313|EMBL:ACT24588.1};
OS   Mycobacterium tuberculosis (strain KZN 1435 / MDR).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC   Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=478434 {ECO:0000313|EMBL:ACT24588.1, ECO:0000313|Proteomes:UP000002737};
RN   [1] {ECO:0000313|Proteomes:UP000002737}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KZN 1435 / MDR {ECO:0000313|Proteomes:UP000002737};
RA   Murray M., Pillay M., Borowsky M.L., Young S.K., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A.M., Borenstein D., Chen Z., Engels R.,
RA   Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA   Heiman D.I., Hepburn T.A., Howarth C., Jen D., Larson L., Lewis B.,
RA   Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.D.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S.N., Walk T., White J.,
RA   Yandava C., Haas B., Nusbaum C., Galagan J., Birren B.;
RT   "The genome sequence of Mycobacterium tuberculosis strain KZN 1435.";
RL   Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001658; ACT24588.1; -; Genomic_DNA.
DR   RefSeq; YP_003031483.1; NC_012943.1.
DR   ProteinModelPortal; C6DN43; -.
DR   STRING; 478434.TBMG_01534; -.
DR   EnsemblBacteria; ACT24588; ACT24588; TBMG_01534.
DR   GeneID; 8163398; -.
DR   KEGG; mtb:TBMG_01534; -.
DR   PATRIC; 18160782; VBIMycTub122270_1695.
DR   eggNOG; COG0388; -.
DR   HOGENOM; HOG000051304; -.
DR   KO; K01950; -.
DR   OMA; CEDIWGD; -.
DR   OrthoDB; EOG6VB6S8; -.
DR   BioCyc; MTUB478434:GH8E-1592-MONOMER; -.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR   GO; GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.620; -; 2.
DR   Gene3D; 3.60.110.10; -; 1.
DR   InterPro; IPR003010; C-N_Hydrolase.
DR   InterPro; IPR014445; Gln-dep_NAD_synthase.
DR   InterPro; IPR022310; NAD/GMP_synthase.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   Pfam; PF00795; CN_hydrolase; 1.
DR   Pfam; PF02540; NAD_synthase; 1.
DR   PIRSF; PIRSF006630; NADS_GAT; 1.
DR   SUPFAM; SSF56317; SSF56317; 1.
DR   PROSITE; PS50263; CN_HYDROLASE; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002737}.
SQ   SEQUENCE   738 AA;  80448 MW;  3D6C9BA4D150FF7E CRC64;
     MGLLGGQSGP RVGSGPVGSI PTPVNAAICQ QRGGFHGVER GYSAGDSGVL TSLGDNERTM
     NFYSAYQHGF VRVAACTHHT TIGDPAANAA SVLDMARACH DDGAALAVFP ELTLSGYSIE
     DVLLQDSLLD AVEDALLDLV TESADLLPVL VVGAPLRHRH RIYNTAVVIH RGAVLGVVPK
     SYLPTYREFY ELRQMAPGDG ERGTIRIGGA DVAFGTDLLF AASDLPGFVL HVEICEDMFV
     PMPPSAEAAL AGATVLANLS GSPITIGRAE DRRLLARSAS ARCLAAYVYA AAGEGESTTD
     LAWDGQTMIW ENGALLAESE RFPKGVRRSV ADVDTELLRS ERLRMGTFDD NRRHHRELTE
     SFRRIDFALD PPAGDIGLLR EVERFPFVPA DPQRLQQDCY EAYNIQVSGL EQRLRALDYP
     KVVIGVSGGL DSTHALIVAT HAMDREGRPR SDILAFALPG FATGEHTKNN AIKLARALGV
     TFSEIDIGDT ARLMLHTIGH PYSVGEKVYD VTFENVQAGL RTDYLFRIAN QRGGIVLGTG
     DLSELALGWS TYGVGDQMSH YNVNAGVPKT LIQHLIRWVI SAGEFGEKVG EVLQSVLDTE
     ITPELIPTGE EELQSSEAKV GPFALQDFSL FQVLRYGFRP SKIAFLAWHA WNDAERGNWP
     PGFPKSERPS YSLAEIRHWL QIFVQRFYSF SQFKRSALPN GPKVSHGGAL SPRGDWRAPS
     DMSARIWLDQ IDREVPKG
//
DBGET integrated database retrieval system