ID   C6E8V6_GEOSM            Unreviewed;       794 AA.
AC   C6E8V6;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   01-MAY-2013, entry version 33.
DE   SubName: Full=NADH dehydrogenase I, D subunit;
GN   OrderedLocusNames=GM21_0160;
OS   Geobacter sp. (strain M21).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=443144;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M21;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ovchinnikova G., Lovley D.;
RT   "Complete sequence of Geobacter sp. M21.";
RL   Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: NDH-1 shuttles electrons from NADH, via FMN and iron-
CC       sulfur (Fe-S) centers, to quinones in the respiratory chain. The
CC       immediate electron acceptor for the enzyme in this species is
CC       believed to be ubiquinone. Couples the redox reaction to proton
CC       translocation (for every two electrons transferred, four hydrogen
CC       ions are translocated across the cytoplasmic membrane), and thus
CC       conserves the redox energy in a proton gradient (By similarity).
CC   -!- CATALYTIC ACTIVITY: NADH + quinone = NAD(+) + quinol.
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DR   EMBL; CP001661; ACT16245.1; -; Genomic_DNA.
DR   RefSeq; YP_003020003.1; NC_012918.1.
DR   STRING; 443144.GM21_0160; -.
DR   EnsemblBacteria; ACT16245; ACT16245; GM21_0160.
DR   GeneID; 8135463; -.
DR   KEGG; gem:GM21_0160; -.
DR   PATRIC; 22014812; VBIGeoSp56140_0162.
DR   eggNOG; COG0649; -.
DR   HOGENOM; HOG000228264; -.
DR   KO; K13380; -.
DR   OMA; VWDMFGI; -.
DR   ProtClustDB; PRK13292; -.
DR   BioCyc; GSP443144:GHKM-164-MONOMER; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   Gene3D; 3.40.50.700; -; 1.
DR   HAMAP; MF_01356; NDH1_NuoB; 1; -.
DR   HAMAP; MF_01357; NDH1_NuoC; 1; -.
DR   HAMAP; MF_01358; NDH1_NuoD; 1; -.
DR   InterPro; IPR010218; NADH_DH_suC.
DR   InterPro; IPR001135; NADH_Q_OxRdtase_suD.
DR   InterPro; IPR006137; NADH_UbQ_OxRdtase-like_20kDa.
DR   InterPro; IPR001268; NADH_UbQ_OxRdtase_30kDa_su.
DR   InterPro; IPR014029; NADH_UbQ_OxRdtase_49kDa_CS.
DR   InterPro; IPR020396; NADH_UbQ_OxRdtase_CS.
DR   InterPro; IPR006138; NADH_UQ_OxRdtase_20Kd_su.
DR   InterPro; IPR022885; NDH1_su_D/H.
DR   Pfam; PF00329; Complex1_30kDa; 1.
DR   Pfam; PF00346; Complex1_49kDa; 1.
DR   Pfam; PF01058; Oxidored_q6; 1.
DR   ProDom; PD001581; NADH_UbQ_OxRdtase_30kDa_su; 1.
DR   TIGRFAMs; TIGR01957; nuoB_fam; 1.
DR   TIGRFAMs; TIGR01962; NuoD; 1.
DR   PROSITE; PS00542; COMPLEX1_30K; 1.
DR   PROSITE; PS00535; COMPLEX1_49K; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane;
KW   Multifunctional enzyme; Ubiquinone.
SQ   SEQUENCE   794 AA;  90049 MW;  E2EED30CCDAE8BB3 CRC64;
     MSQGDDDKIP ENVLFASLDD MINWGRANSL WPMFFGLSCC FVEMMTSFTS RYDVSRFGAE
     VLRGTPRESD LMVIAGTVFK KMAPSILRLY DQMAEPKWVI SMGSCANSGG MYDVYSVVQG
     VDQILPVDLY IPGCPPRPES FLEGLMLLQQ KIRSEERPTR PVLRMQGGTQ GTVAPILVDG
     ATKSRDTRGP GMEGSAIRGS AMQPPHFAAP RSDELWRPKQ TRLPYPDFNL KEELQGAFAG
     QVVLDETACD MLTYRAPARL VPEILRHLKE RKESPFRRLE DIACVDESCR RDRDRYKDFT
     VNYHLTCFDT PGRVRIKTEL EGSYPETPSV TSVFPVADWY EREAYDMFGI RFAGHPNLRR
     ILMPPDWVGH PLRKEHPARA TELPPYTAED ARRQKALPGG DFFDRVDDET LILNLGPQHP
     GTHGVIRFVL KLSGEEIVDM DSDIGYHHRA AEKTGERQNW HQYIPYTDRV DYLSGVQNNL
     AYLNSVETLC GIEIPDRAIY IRVMLCELFR IANHLVWLGT FASDLGAMTP VFYTFTDREK
     IFDIVEFITG GRMHPAWFRI GGVAEDLPEG WQEKVHSFLE WFPARLAEYE KLLTGNPIFV
     ARLKGVSAIT LDTALEWGIS GPNLRACDFA WDLRKKIPYG GYDRFEFEVA TAHGGDCYAR
     YKVRMEEMRQ SLSIVRQAAA GMPGGRFISP DYRYTLPQKR DTLEDIESLI HHFVNATRGI
     SPPKGECYAP IEGSKGEYGY FAVSDGLHTA YRMRIRTATF PHIQSLPVLS RGWLVSDFLA
     ILGSLDFVLS DLDR
//