ID C7MB66_BRAFD Unreviewed; 462 AA.
AC C7MB66;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 01-MAY-2013, entry version 28.
DE SubName: Full=Folylpolyglutamate synthase/dihydrofolate synthase;
GN OrderedLocusNames=Bfae_09900;
OS Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / NCIB 9860).
OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC Micrococcineae; Dermabacteraceae; Brachybacterium.
OX NCBI_TaxID=446465;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43885 / DSM 4810 / NCIB 9860;
RX PubMed=21304631; DOI=10.4056/sigs.492;
RA Lapidus A., Pukall R., Labuttii K., Copeland A., Del Rio T.G.,
RA Nolan M., Chen F., Lucas S., Tice H., Cheng J.F., Bruce D.,
RA Goodwin L., Pitluck S., Rohde M., Goker M., Pati A., Ivanova N.,
RA Mavrommatis K., Chen A., Palaniappan K., D'haeseleer P., Chain P.,
RA Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C.,
RA Klenk H.P.;
RT "Complete genome sequence of Brachybacterium faecium type strain
RT (Schefferle 6-10).";
RL Stand. Genomic Sci. 1:3-11(2009).
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DR EMBL; CP001643; ACU84839.1; -; Genomic_DNA.
DR RefSeq; YP_003154429.1; NC_013172.1.
DR STRING; 446465.Bfae_09900; -.
DR EnsemblBacteria; ACU84839; ACU84839; Bfae_09900.
DR GeneID; 8399538; -.
DR KEGG; bfa:Bfae_09900; -.
DR PATRIC; 21173641; VBIBraFae133938_0984.
DR eggNOG; COG0285; -.
DR HOGENOM; HOG000019980; -.
DR KO; K11754; -.
DR OMA; MEKAGIF; -.
DR BioCyc; BFAE446465:GH3P-987-MONOMER; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:InterPro.
DR GO; GO:0046901; P:tetrahydrofolylpolyglutamate biosynthetic process; IEA:GOC.
DR Gene3D; 3.40.1190.10; -; 1.
DR Gene3D; 3.90.190.20; -; 1.
DR InterPro; IPR001645; Folylpolyglutamate_synth.
DR InterPro; IPR018109; Folylpolyglutamate_synth_CS.
DR InterPro; IPR004101; Mur_ligase_C.
DR InterPro; IPR013221; Mur_ligase_cen.
DR PANTHER; PTHR11136; PTHR11136; 1.
DR Pfam; PF02875; Mur_ligase_C; 1.
DR Pfam; PF08245; Mur_ligase_M; 1.
DR PIRSF; PIRSF001563; Folylpolyglu_synth; 1.
DR SUPFAM; SSF53244; Mur_ligase_C; 1.
DR SUPFAM; SSF53623; Mur_ligase_cen; 1.
DR TIGRFAMs; TIGR01499; folC; 1.
DR PROSITE; PS01011; FOLYLPOLYGLU_SYNT_1; 1.
PE 4: Predicted;
KW ATP-binding; Complete proteome; Nucleotide-binding.
SQ SEQUENCE 462 AA; 48871 MW; 5319F067DD9369B5 CRC64;
MQNSPRPGSS PQAMSPELRE VYAALLERAP ENRIEPDLSR ITRVMELMGD PQNSYRSIRI
AGTNGKTTTA RILERILREA GLRTGRTTSP HLRSPVERIA IDGASIDEEG FLQAYHDVAP
FAAIVDAEQE AAGGVPLTYF EYLTAMAFQA FASAPVDVAV IETGLGGTWD ATGAVHPDVA
VITPISLDHQ DYLGDTIAEI AAEKAGILTA EATAILASQP YEDAADVLRE RIGELGAEAA
VEDQQIGVLS HTPGVGGQML SLQGIAGRYE EVFLSLLGEH QARNALLAVA AAEALLGDGR
TPLGGELLSA ALSSVTSPGR AEVVRQAPTI LLDAAHNPAG ALTLVETVRE NFRFTRTVGL
VGILREKDAA EILDVLEPLL DSVVITQSSS PRAIPTDVLA DIARDIFQDE DRVVERASLP
DAIQAAVDLA ETDGDQFGGV VVAGSVTLTG EVRELLGVPE EE
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