ID C7NGZ7_KYTSD Unreviewed; 395 AA.
AC C7NGZ7;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 01-MAY-2013, entry version 35.
DE RecName: Full=Acetate kinase;
DE EC=2.7.2.1;
DE AltName: Full=Acetokinase;
GN Name=ackA; OrderedLocusNames=Ksed_11270;
OS Kytococcus sedentarius (strain ATCC 14392 / DSM 20547 / CCM 314 / 541)
OS (Micrococcus sedentarius).
OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC Micrococcineae; Dermacoccaceae; Kytococcus.
OX NCBI_TaxID=478801;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14392 / DSM 20547 / CCM 314 / 541;
RX PubMed=21304632; DOI=10.4056/sigs.761;
RA Sims D., Brettin T., Detter J.C., Han C., Lapidus A., Copeland A.,
RA Glavina Del Rio T., Nolan M., Chen F., Lucas S., Tice H., Cheng J.F.,
RA Bruce D., Goodwin L., Pitluck S., Ovchinnikova G., Pati A.,
RA Ivanova N., Mavrommatis K., Chen A., Palaniappan K., D'haeseleer P.,
RA Chain P., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Schneider S., Goker M., Pukall R., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Kytococcus sedentarius type strain
RT (541).";
RL Stand. Genomic Sci. 1:12-20(2009).
CC -!- FUNCTION: Catalyzes the formation of acetyl phosphate from acetate
CC and ATP. Can also catalyze the reverse reaction (By similarity).
CC -!- CATALYTIC ACTIVITY: ATP + acetate = ADP + acetyl phosphate.
CC -!- COFACTOR: Mg(2+). Can also accept Mn(2+) (By similarity).
CC -!- PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA
CC biosynthesis; acetyl-CoA from acetate: step 1/2.
CC -!- SUBUNIT: Homodimer (By similarity).
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the acetokinase family.
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DR EMBL; CP001686; ACV06167.1; -; Genomic_DNA.
DR RefSeq; YP_003148932.1; NC_013169.1.
DR ProteinModelPortal; C7NGZ7; -.
DR STRING; 478801.Ksed_11270; -.
DR EnsemblBacteria; ACV06167; ACV06167; Ksed_11270.
DR GeneID; 8372635; -.
DR KEGG; kse:Ksed_11270; -.
DR PATRIC; 22191911; VBIKytSed14067_1071.
DR eggNOG; COG0282; -.
DR HOGENOM; HOG000288399; -.
DR KO; K00925; -.
DR OMA; VEQTENT; -.
DR BioCyc; KSED478801:GI4L-1122-MONOMER; -.
DR UniPathway; UPA00340; UER00458.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008776; F:acetate kinase activity; IEA:HAMAP.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006085; P:acetyl-CoA biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006082; P:organic acid metabolic process; IEA:InterPro.
DR HAMAP; MF_00020; Acetate_kinase; 1; -.
DR InterPro; IPR004372; Ac/Proprionate_kinase.
DR InterPro; IPR000890; Aliphatic_acid_kin_short-chain.
DR InterPro; IPR023865; Aliphatic_acid_kinase_CS.
DR PANTHER; PTHR21060; PTHR21060; 1.
DR Pfam; PF00871; Acetate_kinase; 1.
DR PIRSF; PIRSF000722; Acetate_prop_kin; 1.
DR PRINTS; PR00471; ACETATEKNASE.
DR TIGRFAMs; TIGR00016; ackA; 1.
DR PROSITE; PS01075; ACETATE_KINASE_1; 1.
DR PROSITE; PS01076; ACETATE_KINASE_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; Cytoplasm; Kinase; Magnesium;
KW Metal-binding; Nucleotide-binding; Transferase.
FT NP_BIND 203 207 ATP (By similarity).
FT NP_BIND 276 278 ATP (By similarity).
FT NP_BIND 324 328 ATP (By similarity).
FT ACT_SITE 143 143 Proton donor/acceptor (By similarity).
FT METAL 7 7 Magnesium (By similarity).
FT METAL 381 381 Magnesium (By similarity).
FT BINDING 14 14 ATP (By similarity).
FT BINDING 86 86 Substrate (By similarity).
FT SITE 175 175 Transition state stabilizer (By
FT similarity).
FT SITE 236 236 Transition state stabilizer (By
FT similarity).
SQ SEQUENCE 395 AA; 41677 MW; 89DC9CB061394242 CRC64;
MSALVINAGS SSVKFQVVDP ATGAVRAKGL AERIGETEGA ATIEQEGQGE QSTSQPFADH
RAALAWVLDQ LGGAGLLADV EVVGHRTVHG GRRFDRPVVL DDETLAVLRE LSPLAPLHNP
ANIEGIEAAR EQLPEVPHVS VFDTGFFAEL PPEVRTYAID TEVAQEYAVQ RYGFHGASHA
YVSQRAAEDL GRDPAELKVI VLHLGNGASA AAVDGGRPVD CSMGMTPLEG LVMGTRPGDI
DPGVLLHLLR HGLDADELDD LLNRRSGLKG LTGTNDMREV RAAATAGDER ARLALDVSIH
RIVRYVGAFH AVMGGLDALV FTAGVGENNV ELRAEVCERL AVLGIRLDAG RNTSVPRGRP
GSTVVSGDDS QVAVLVTPTN EELYIARAAA ATVTP
//
