ID C7RNJ8_ACCPU Unreviewed; 461 AA.
AC C7RNJ8;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 01-MAY-2013, entry version 25.
DE RecName: Full=Argininosuccinate lyase;
DE Short=ASAL;
DE EC=4.3.2.1;
DE AltName: Full=Arginosuccinase;
GN Name=argH; OrderedLocusNames=CAP2UW1_0789;
OS Accumulibacter phosphatis (strain UW-1).
OC Bacteria; Proteobacteria; Betaproteobacteria;
OC Candidatus Accumulibacter.
OX NCBI_TaxID=522306;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UW-1;
RG US DOE Joint Genome Institute;
RA Martin H.G., Ivanova N., Kunin V., Warnecke F., Barry K., He S.,
RA Salamov A., Szeto E., Dalin E., Pangilinan J.L., Lapidus A., Lowry S.,
RA Kyrpides N.C., McMahon K.D., Hugenholtz P.;
RT "Complete sequence of chromosome of Candidatus Accumulibacter
RT phosphatis clade IIA str. UW-1.";
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY: 2-(N(omega)-L-arginino)succinate = fumarate +
CC L-arginine.
CC -!- PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; L-
CC arginine from L-ornithine and carbamoyl phosphate: step 3/3.
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the lyase 1 family. Argininosuccinate lyase
CC subfamily.
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DR EMBL; CP001715; ACV34134.1; -; Genomic_DNA.
DR RefSeq; YP_003166063.1; NC_013194.1.
DR ProteinModelPortal; C7RNJ8; -.
DR STRING; 522306.CAP2UW1_0789; -.
DR EnsemblBacteria; ACV34134; ACV34134; CAP2UW1_0789.
DR GeneID; 8402924; -.
DR KEGG; app:CAP2UW1_0789; -.
DR PATRIC; 21257596; VBICanAcc132554_1061.
DR eggNOG; COG0165; -.
DR HOGENOM; HOG000242744; -.
DR KO; K01755; -.
DR ProtClustDB; PRK00855; -.
DR BioCyc; APHO522306:GHXL-798-MONOMER; -.
DR UniPathway; UPA00068; UER00114.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004056; F:argininosuccinate lyase activity; IEA:HAMAP.
DR GO; GO:0042450; P:arginine biosynthetic process via ornithine; IEA:InterPro.
DR Gene3D; 1.10.275.10; -; 1.
DR HAMAP; MF_00006; Arg_succ_lyase; 1; -.
DR InterPro; IPR009049; Argininosuccinate_lyase.
DR InterPro; IPR003031; D_crystallin.
DR InterPro; IPR024083; Fumarase/histidase_N.
DR InterPro; IPR000362; Fumarate_lyase.
DR InterPro; IPR020557; Fumarate_lyase_CS.
DR InterPro; IPR022761; Fumarate_lyase_N.
DR InterPro; IPR008948; L-Aspartase-like.
DR PANTHER; PTHR11444:SF3; PTHR11444:SF3; 1.
DR Pfam; PF00206; Lyase_1; 1.
DR PRINTS; PR00145; ARGSUCLYASE.
DR PRINTS; PR00149; FUMRATELYASE.
DR SUPFAM; SSF48557; L-Aspartase-like; 1.
DR TIGRFAMs; TIGR00838; argH; 1.
DR PROSITE; PS00163; FUMARATE_LYASES; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis; Arginine biosynthesis; Complete proteome;
KW Cytoplasm; Lyase.
SQ SEQUENCE 461 AA; 51221 MW; 904F5D16FD520FCE CRC64;
MNPSDSPQYT WAGRFSEPMS EVVKRYTASV AFDRRLWRHD IRASLAHATM LARQEIISAA
DLADIERGMA QIAEEIETGT FVWSLDLEDV HLNIEKRLTT LVGDAGKRLH TGRSRNDQVA
TDIRLYLRDA IDDILSLLKQ FQSRLLDLAE AEAATPLPGF THLQVAQPVT FGHHLLAYFE
MTRRDAERFV DCRRRTNRLP LGAAALAGTS YPIDRHLVAE LLGFDGVCEN SLDAVADRDF
AIEFCGASAL VMMHLSRLSE ELVLWMNPRF GFITIADRFC TGSSIMPQKR NPDVPELARG
KTGRVYGHLM ALLTLMKGQP LAYNKDNQED KEPLFDAVDT VTDTLRIFAE MIAGISTRPE
NMRDALRQGY ATATDLADYL AHRGLPFRDA HAVVGLAVRH AEALGVDLSE LALADLRQFS
ALIDEDVFKA LTVDGSLAAR NHIGGTAPEQ VLAAIARARR K
//
